Matrix-embedded cells control osteoclast formation (Q28247746)

1

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Melda Onal

2

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Robert L Jilka

3

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Robert S Weinstein

4

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Stavros C Manolagas

5

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Charles A O'Brien

6

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language of work or name

English

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publication date

11 September 2011

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published in

Nature Medicine

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volume

17

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issue

10

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page(s)

1235-41

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cites work

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

20 March 2017

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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VEGFA is necessary for chondrocyte survival during bone development

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

20 March 2017

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Genetic regulation of osteoclast development and function

7 April 2017

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Developmental regulation of the growth plate

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Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

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Activation of bone remodeling after fatigue: differential response to linear microcracks and diffuse damage

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Commitment to the osteoblast lineage is not required for RANKL gene expression

29 September 2017

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Action of RANKL and OPG for osteoclastogenesis.

29 September 2017

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Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption

29 September 2017

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Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter

29 September 2017

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Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

29 September 2017

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Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease.

29 September 2017

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Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2

29 September 2017

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DMP1-targeted Cre expression in odontoblasts and osteocytes

29 September 2017

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Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts

29 September 2017

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PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

29 September 2017

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“Whither flows the fluid in bone?” An osteocyte's perspective

29 September 2017

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MLO-Y4 osteocyte-like cells support osteoclast formation and activation

29 September 2017

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Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids

29 September 2017

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Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression

29 September 2017

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A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy

29 September 2017

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STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroi

29 September 2017

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Dissociation between bone resorption and bone formation in osteopenic transgenic mice

29 September 2017

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Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone

29 September 2017

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Role of osteoblasts in hormonal control of bone resorption—A hypothesis

29 September 2017

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Osteoblastic cells are involved in osteoclast formation.

2 June 2018

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Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL.

2 June 2018

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Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

27 November 2018

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Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL.

27 November 2018

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Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

27 November 2018

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Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

27 November 2018

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IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice.

27 November 2018

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Osteoprotegerin deficiency and juvenile Paget's disease

27 November 2018

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Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

27 November 2018

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12 December 2020

Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis

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12 December 2020

Expression of Cre recombinase in the developing mouse limb bud driven by aPrxl enhancer

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12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

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12 December 2020

Continuous activation of G alpha q in osteoblasts results in osteopenia through impaired osteoblast differentiation

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12 December 2020

Identifiers

DOI

10.1038/NM.2448

1 reference

Dimensions Publication ID

1033717400

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1 reference

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PubMed publication ID

21909103

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