Mechanism of action of novel NO-releasing furoxan derivatives of aspirin in human platelets (Q28218042)

6

0 references

author name string

Catriona M Turnbull

1

0 references

Clara Cena

2

0 references

Alberto Gasco

4

0 references

Adriano G Rossi

British Journal of Pharmacology

5

0 references

language of work or name

English

0 references

publication date

June 2006

0 references

published in

0 references

volume

148

0 references

issue

4

0 references

page(s)

517-26

0 references

cites work

Direct and irreversible inhibition of cyclooxygenase-1 by nitroaspirin (NCX 4016)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nitroaspirin plus clopidogrel versus aspirin plus clopidogrel against platelet thromboembolism and intimal thickening in mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

NO-aspirin: mechanism of action and gastrointestinal safety

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Vascular protective actions of a nitric oxide aspirin analog in both in vitro and in vivo models of diabetes mellitus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Final report on the aspirin component of the ongoing Physicians' Health Study

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Endothelial nitric oxide synthase, caveolae and the development of atherosclerosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

ABC of the upper gastrointestinal tract: Indigestion and non-steroidal anti-inflammatory drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Effects of nitric oxide-releasing aspirin versus aspirin on restenosis in hypercholesterolemic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nitric oxide in mucosal defense: a little goes a long way.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

A common pathway for nitric oxide release from NO-aspirin and glyceryl trinitrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Aspirin as an antiplatelet drug

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Systemic nature of endothelial dysfunction in atherosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Mechanisms of nonsteroidal anti-inflammatory drug-induced gastric damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nitroprusside in vitro inhibits platelet aggregation and intracellular calcium translocation. Effect of haemoglobin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Mechanisms of platelet activation: thromboxane A2 as an amplifying signal for other agonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

An L-arginine/nitric oxide pathway present in human platelets regulates aggregation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Aspirin and gastric ulcer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Mechanisms underlying gastric mucosal damage induced by indomethacin and bile-salts, and the actions of prostaglandins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Acetylation of prostaglandin synthase by aspirin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Inhibition of platelet prostaglandin synthetase by oral aspirin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Gastric irritancy of aspirin and its congeners: anti-inflammatory activity without this side-effect

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

A potential role for extracellular nitric oxide generation in cGMP-independent inhibition of human platelet aggregation: biochemical and pharmacological considerations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Evidence for a cyclic GMP-independent mechanism in the anti-platelet action of S-nitrosoglutathione

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

The antiplatelet effects of a new nitroderivative of acetylsalicylic acid--an in vitro study of inhibition on the early phase of platelet activation and on TXA2 production.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Antiaggregating and vasodilatory effects of a new nitroderivative of acetylsalicylic acid

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Antiplatelet drugs and generation of thrombin in clotting blood

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Novel role for low molecular weight plasma thiols in nitric oxide-mediated control of platelet function

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Comparison of anti-aggregatory effects of PGI2, PGI3 and iloprost on human and rabbit platelets

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751793

Nitric Oxide Inhibits Capacitative Cation Influx in Human Platelets by Promoting Sarcoplasmic/Endoplasmic Reticulum Ca 2+ -ATPase–Dependent Refilling of Ca 2+ Stores

27 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0706743

Nitric oxide regulates monocyte chemotactic protein-1

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0706743

Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2.ISIS-2 (Second International Study of Infarct Survival) Collaborative Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Detection of glutathione thiyl free radical catalyzed by prostaglandin H synthase present in keratinocytes. Study of co-oxidation in a cellular system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

A prospective study of aspirin use and primary prevention of cardiovascular disease in women

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Measurement of thrombin generation in whole blood--the effect of heparin and aspirin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Quantitative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Endothelial nitric oxide synthase modulates gastric ulcer healing in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Inhibition of Human Platelet Aggregation by Nitric Oxide Donor Drugs: Relative Contribution of cGMP-Independent Mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020

Biotransformation of glyceryl trinitrate by blood platelets as compared to vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16702997

12 December 2020