Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations (Q28141005)

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C Bontekoe

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C E Bakker

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L van Unen

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B Anar

5

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R Willemsen

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H Galjaard

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B A Oostra

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A T Hoogeveen

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

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language of work or name

English

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publication date

May 1999

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language of work

Human Molecular Genetics

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volume

8

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issue

5

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page(s)

863-9

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cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Absence of expression of the FMR-1 gene in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The fragile X mental retardation protein is associated with ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

FMRP is associated to the ribosomes via RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

A point mutation in the FMR-1 gene associated with fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Analysis of domains affecting intracellular localization of the FMRP protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Association of FMRP with ribosomal precursor particles in the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Identification of a signal for rapid export of proteins from the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

CRM1 is an export receptor for leucine-rich nuclear export signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Exportin 1 (Crm1p) is an essential nuclear export factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Evidence for a role of CRM1 in signal-mediated nuclear protein export

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

hnRNP proteins and the biogenesis of mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Nucleolar necklaces in chick embryo myoblasts formed by lack of arginine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Drug-induced dispersal of transcribed rRNA genes and transcriptional products: immunolocalization and silver staining of different nucleolar components in rat cells treated with 5,6-dichloro-beta-D-ribofuranosylbenzimidazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Nucleocytoplasmic transport of the Rev protein of human immunodeficiency virus type 1 is dependent on the activation domain of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Nucleolar Localization of myc Transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863

A human nucleoporin-like protein that specifically interacts with HIV Rev

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.5.863