MicroRNA silencing through RISC recruitment of eIF6 (Q28118262)

4 January 2017

title

MicroRNA silencing through RISC recruitment of eIF6 (English)

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Eukaryotic translation initiation factor 6

4 January 2017

main subject

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Mov10 RISC complex RNA helicase

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gene silencing by miRNA

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Eukaryotic translation initiation factor 6 CELE_C47B2.5

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7

Amy E. Pasquinelli

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4 January 2017

author name string

Thimmaiah P. Chendrimada

1

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4 January 2017

Kenneth J. Finn

2

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4 January 2017

Xinjun Ji

3

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4 January 2017

David Baillat

4

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4 January 2017

Richard I. Gregory

5

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4 January 2017

Stephen A. Liebhaber

6

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4 January 2017

Ramin Shiekhattar

8

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4 January 2017

language of work or name

English

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publication date

14 June 2007

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4 January 2017

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4 January 2017

volume

447

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4 January 2017

issue

7146

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4 January 2017

page(s)

823–828

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MicroRNA biogenesis: coordinated cropping and dicing

4 January 2017

cites work

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

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How do microRNAs regulate gene expression?

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Control of translation and mRNA degradation by miRNAs and siRNAs

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RISC assembly defects in the Drosophila RNAi mutant armitage.

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Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

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7 January 2021

Molecular cloning and functional expression of a human cDNA encoding translation initiation factor 6

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Identification of novel argonaute-associated proteins

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The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis

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Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5. 8S RRNA processing and 60S ribosome biogenesis

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The Saccharomyces cerevisiae homologue of mammalian translation initiation factor 6 does not function as a translation initiation factor

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The beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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7 January 2021

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

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The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

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Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

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The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans.

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7 January 2021

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

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7 January 2021

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

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7 January 2021

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7 January 2021

MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

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7 January 2021

Short RNAs repress translation after initiation in mammalian cells.

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7 January 2021

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

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7 January 2021

A combined computational-experimental approach predicts human microRNA targets

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7 January 2021

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7 January 2021