Metabolic insights from zebrafish genetics, physiology, and chemical biology (Q28084257)

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26 February 2020

review article

2 references

22 August 2022

Metabolic insights from zebrafish genetics, physiology, and chemical biology (English)

2 references

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26 February 2020

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biomedical investigative technique

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22 October 2019

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26 February 2020

author name string

Philipp Gut

series ordinal

2

2 references

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26 February 2020

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4 January 2015

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Cellular and Molecular Life Sciences

26 February 2020

1 June 2015

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22 October 2019

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26 February 2020

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26 February 2020

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12

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26 February 2020

page(s)

2249-2260

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Creative Commons Attribution 4.0 International

26 February 2020

copyright license

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Making designer mutants in model organisms

22 August 2022

cites work

1 reference

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Whole organism high content screening identifies stimulators of pancreatic beta-cell proliferation

20 March 2017

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Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals

20 March 2017

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Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis

20 March 2017

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Efficient genome editing in zebrafish using a CRISPR-Cas system

20 March 2017

1 reference

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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

20 March 2017

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

20 March 2017

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Studying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiology

20 March 2017

1 reference

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Selective plane illumination microscopy techniques in developmental biology

20 March 2017

1 reference

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

20 March 2017

1 reference

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Projections of global mortality and burden of disease from 2002 to 2030

20 March 2017

1 reference

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Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

20 March 2017

1 reference

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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

20 March 2017

1 reference

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Lipoprotein particles are required for Hedgehog and Wingless signalling

20 March 2017

1 reference

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Overexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafish

20 March 2017

1 reference

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Identification of novel inhibitors of dietary lipid absorption using zebrafish

20 March 2017

1 reference

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Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

20 March 2017

1 reference

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Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013

20 March 2017

1 reference

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National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

7 April 2017

1 reference

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10-year follow-up of intensive glucose control in type 2 diabetes

7 April 2017

1 reference

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Molecular mediators of hepatic steatosis and liver injury

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering

7 April 2017

1 reference

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Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases

29 September 2017

1 reference

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Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia

29 September 2017

1 reference

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Thyroid hormone-dependent adult pigment cell lineage and pattern in zebrafish.

29 September 2017

1 reference

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Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting

29 September 2017

1 reference

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Characterization of Cre recombinase models for the study of adipose tissue

29 September 2017

1 reference

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Lxr-driven enterocyte lipid droplet formation delays transport of ingested lipids.

29 September 2017

1 reference

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World Gastroenterology Organisation global guidelines: Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Parp inhibition prevents ten-eleven translocase enzyme activation and hyperglycemia-induced DNA demethylation

29 September 2017

1 reference

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Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair.

29 September 2017

1 reference

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Generation and characterization of a transgenic zebrafish expressing the reverse tetracycline transactivator

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

The nexus of chromatin regulation and intermediary metabolism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

29 September 2017

1 reference

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X-ray phase-contrast in vivo microtomography probes new aspects of Xenopus gastrulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Metabolomics of developing zebrafish embryos using gas chromatography- and liquid chromatography-mass spectrometry.

29 September 2017

1 reference

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Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.

29 September 2017

1 reference

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Nutrient excess stimulates β-cell neogenesis in zebrafish

29 September 2017

1 reference

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ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1.

29 September 2017

1 reference

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A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting

29 September 2017

1 reference

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Heritable transmission of diabetic metabolic memory in zebrafish correlates with DNA hypomethylation and aberrant gene expression

29 September 2017

1 reference

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29 September 2017

1 reference

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In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

29 September 2017

1 reference

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Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation

29 September 2017

1 reference

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Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia

29 September 2017

1 reference

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Convergence of the insulin and serotonin programs in the pancreatic β-cell

29 September 2017

1 reference

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Fasted zebrafish mimic genetic and physiological responses in mammals: a model for obesity and diabetes?

29 September 2017

1 reference

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Structural and biophysical insight into cholesteryl ester-transfer protein

29 September 2017

1 reference

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Zebrafish obesogenic test: a tool for screening molecules that target adiposity

29 September 2017

1 reference

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Human fatty liver disease: old questions and new insights

29 September 2017

1 reference

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The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish

29 September 2017

1 reference

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Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing β-cells.

29 September 2017

1 reference

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Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish

29 September 2017

1 reference

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Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

29 September 2017

1 reference

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White adipose tissue development in zebrafish is regulated by both developmental time and fish size

29 September 2017

1 reference

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Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation

29 September 2017

1 reference

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Serotonin regulates pancreatic beta cell mass during pregnancy

29 September 2017

1 reference

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Adenosine A(2A) agonist administration improves islet transplant outcome: Evidence for the role of innate immunity in islet graft rejection

29 September 2017

1 reference

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Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling

29 September 2017

1 reference

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Growth and survival of zebrafish (Danio rerio) fed different commercial and laboratory diets

29 September 2017

1 reference

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Regeneration of the pancreas in adult zebrafish

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio).

29 September 2017

1 reference

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Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish

29 September 2017

1 reference

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Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail

29 September 2017

1 reference

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The evolution of plasma cholesterol: direct utility or a "spandrel" of hepatic lipid metabolism?

29 September 2017

1 reference

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Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Adenosine receptor activation ameliorates type 1 diabetes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

In vivo drug discovery in the zebrafish

29 September 2017

1 reference

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Site-1 protease is required for cartilage development in zebrafish

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Formation of the digestive system in zebrafish. II. Pancreas morphogenesis.

29 September 2017

1 reference

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The art and design of genetic screens: zebrafish

29 September 2017

1 reference

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Differential induction of four msx homeobox genes during fin development and regeneration in zebrafish

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Plasma lipoproteins in fish

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Metabolic regulation of cellular plasticity in the pancreas

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Metabolic profile analysis of zebrafish embryos.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Adenosine signaling promotes regeneration of pancreatic β cells in vivo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

A chemical screening system for glucocorticoid stress hormone signaling in an intact vertebrate

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

Limb regeneration is impaired in an adult zebrafish model of diabetes mellitus

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4439526

National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5·4 million participants

2 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Heritable gene targeting in zebrafish using customized TALENs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Developmental expression and nutritional regulation of a zebrafish gene homologous to mammalian microsomal triglyceride transfer protein large subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Control of angiogenesis by AIBP-mediated cholesterol efflux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Lrp13 is a novel vertebrate lipoprotein receptor that binds vitellogenins in teleost fishes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Fructose leads to hepatic steatosis in zebrafish that is reversed by mechanistic target of rapamycin (mTOR) inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Local reorganization of xanthophores fine-tunes and colors the striped pattern of zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Selective expression of an aP2/Fatty Acid Binding Protein 4-Cre transgene in non-adipogenic tissues during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Vitellogenin expression in white adipose tissue in female teleost fish

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Larval zebrafish as a model for glucose metabolism: expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Identifying proteins in zebrafish embryos using spectral libraries generated from dissected adult organs and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1816-8

Turmeric and laurel aqueous extracts exhibit in vitro anti-atherosclerotic activity and in vivo hypolipidemic effects in a zebrafish model

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25556679

12 December 2020

Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish

1 reference

https://pubmed.ncbi.nlm.nih.gov/25556679

12 December 2020

The evolution of endothermy is explained by thyroid hormone-mediated responses to cold in early vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/25556679

12 December 2020

Growth and body composition of zebrafish (Danio rerio) larvae fed a compound feed from first feeding onward: toward implications on nutrient requirements

1 reference

https://pubmed.ncbi.nlm.nih.gov/25556679

12 December 2020

10.1007/S00018-014-1816-8

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25556679%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25556679%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

25556679

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25556679%20AND%20SRC:MED&resulttype=core&format=json