Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. (Q27932969)

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English	Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.	scientific article

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1 December 2016

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13 January 2020

Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast (English)

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13 January 2020

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GOA release 2020-03-11

Phosphatidylinositol/phosphatidylcholine transfer protein SEC14 YMR079W

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GOA release 2020-03-11

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based on heuristic

inferred from title

Carl J. Mousley

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13 January 2020

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13 January 2020

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Markus R Wenk

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13 January 2020

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Kimberly Tyeryar

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13 January 2020

Kristina E Ile

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13 January 2020

Renee L Brost

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13 January 2020

Charles Boone

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13 January 2020

Vytas A Bankaitis

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27 August 2008

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13 January 2020

Molecular Biology of the Cell

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1 December 2016

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13 January 2020

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13 January 2020

4785-4803

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13 January 2020

The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit

1 reference

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Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis

1 reference

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Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily

1 reference

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Isc1 regulates sphingolipid metabolism in yeast mitochondria.

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Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae

1 reference

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Btn2, a Hook1 ortholog and potential Batten disease-related protein, mediates late endosome-Golgi protein sorting in yeast

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Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT

1 reference

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Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1.

1 reference

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Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae

1 reference

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The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast

1 reference

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Mutants in trs120 disrupt traffic from the early endosome to the late Golgi

1 reference

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Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast.

1 reference

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Structural mechanism for sterol sensing and transport by OSBP-related proteins

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Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recycling

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Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

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Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response

1 reference

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Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution

1 reference

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20 March 2017

Global mapping of the yeast genetic interaction network

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20 March 2017

Molecular machinery for non-vesicular trafficking of ceramide

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20 March 2017

LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway

1 reference

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Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae

1 reference

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20 March 2017

Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex

1 reference

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20 March 2017

Functional organization of the yeast proteome by systematic analysis of protein complexes

1 reference

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20 March 2017

Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae

1 reference

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C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p

1 reference

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20 March 2017

Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo

1 reference

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20 March 2017

Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae

1 reference

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Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases

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Cloning and characterization of a Saccharomyces cerevisiae alkaline ceramidase with specificity for dihydroceramide

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Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity

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Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae

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Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p

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20 March 2017

Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo.

1 reference

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A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae

1 reference

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Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy

1 reference

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Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures

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20 March 2017

Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) in Saccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain

1 reference

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20 March 2017

The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism

1 reference

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Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein

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The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

1 reference

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20 March 2017

Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

1 reference

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tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

1 reference

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1 reference

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A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae

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20 March 2017

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1 reference

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20 March 2017

SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER.

1 reference

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20 March 2017

Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae.

1 reference

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20 March 2017

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

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20 March 2017

Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2.

1 reference

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The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity

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Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

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Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

1 reference

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20 March 2017

Transformation of intact yeast cells treated with alkali cations

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20 March 2017

The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex

1 reference

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20 March 2017

An essential role for a phospholipid transfer protein in yeast Golgi function

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20 March 2017

Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein

1 reference

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20 March 2017

IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae

1 reference

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20 March 2017

One-step gene disruption in yeast

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A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

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20 March 2017

Systematic genetic analysis with ordered arrays of yeast deletion mutants

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20 March 2017

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

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20 March 2017

Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects

1 reference

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20 March 2017

Phosphoinositide kinases

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7 April 2017

Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Nutritional control via Tor signaling in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Heat shock response relieves ER stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Conformational dynamics of the major yeast phosphatidylinositol transfer protein sec14p: insight into the mechanisms of phospholipid exchange and diseases of sec14p-like protein deficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Local polarity and hydrogen bonding inside the Sec14p phospholipid-binding cavity: high-field multi-frequency electron paramagnetic resonance studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Functions and metabolism of sphingolipids in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

The diverse biological functions of phosphatidylinositol transfer proteins in eukaryotes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis thaliana root hairs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Role of the unfolded protein response pathway in regulation of INO1 and in the sec14 bypass mechanism in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

The Tlg SNARE complex is required for TGN homotypic fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Phosphoinositides in membrane traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

The syntaxin Tlg1p mediates trafficking of chitin synthase III to polarized growth sites in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Sphingolipids with inositolphosphate-containing head groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

A phosphatidylinositol transfer protein controls the phosphatidylcholine content of yeast Golgi membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Parallel secretory pathways to the cell surface in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

[12] One-step gene disruption in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Cloning and characterization of Kluyveromyces lactis SEC14, a gene whose product stimulates Golgi secretory function in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

29 September 2017

Translational attenuation mediated by an mRNA intron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

2 June 2018

Translational regulation of yeast GCN4. A window on factors that control initiator-trna binding to the ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

2 June 2018

Endopolyphosphatases for long chain inorganic polyphosphate in yeast and mammals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

2 June 2018

The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

2 June 2018

The chemistry of phospholipid binding by the Saccharomyces cerevisiae phosphatidylinositol transfer protein Sec14p as determined by EPR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

27 November 2018

Coordinate regulation of multiple and distinct biosynthetic pathways by TOR and PKA kinases in S. cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

27 November 2018

Endopolyphosphatase in Saccharomyces cerevisiae undergoes post-translational activations to produce short-chain polyphosphates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575146

27 November 2018

Distinct domains within yeast Sec61p involved in post-translational translocation and protein dislocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a late Golgi compartment from Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipid transfer proteins: a biological debut

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 4-phosphate is required for translation initiation in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative proteomics analysis of the secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization, quantification and subcellular localization of inositol-containing sphingolipids of the yeast, Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The extraction of inositol-containing phospholipids and phosphatidylcholine from Saccharomyces cerevisiae and Neurospora crassa

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E08-04-0426

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753406%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753406%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18753406%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

ResearchGate publication ID

0 references

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