Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. (Q27852067)

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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Language	Label	Description	Also known as
English	Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.	scientific article	Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Statements

scholarly article

1 reference

PubMed publication ID

13 November 2016

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL. (English)

1 reference

PubMed publication ID

13 November 2016

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1 reference

ChEBI release 2020-05-28

16

object named as

Raul Rabadan

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Hossein Khiabanian

4

object named as

Hossein Khiabanian

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Martin S. Tallman

10

object named as

Martin S Tallman

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Elisabeth Paietta

7

object named as

Elisabeth Paietta

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Renate Kirschner-Schwabe

14

object named as

Renate Kirschner-Schwabe

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Zachary Carpenter

3

object named as

Zachary Carpenter

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Arianne Perez-Garcia

2

object named as

Arianne Perez-Garcia

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Maddalena Paganin

11

object named as

Maddalena Paganin

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12

object named as

Giuseppe Basso

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Teresa Palomero

15

object named as

Teresa Palomero

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Adolfo A Ferrando

17

object named as

Adolfo Ferrando

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Valeria Tosello

5

object named as

Valeria Tosello

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Maddalena Allegretta

6

object named as

Maddalena Allegretta

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author name string

Gannie Tzoneva

1

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Janis Racevskis

8

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Jacob M Rowe

9

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Jana Hof

13

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language of work or name

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publication date

March 2013

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Nature Medicine

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19

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3

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368-71

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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

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20 March 2017

Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia

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20 March 2017

Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway

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High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP

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Molecular cloning of human cytosolic purine 5'-nucleotidase

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20 March 2017

Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine-rich motif

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20 March 2017

Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group

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ETV6 mutations in early immature human T cell leukemias

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29 September 2017

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

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29 September 2017

Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984-2001: a report from the children's oncology group

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29 September 2017

WT1 mutations in T-ALL

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29 September 2017

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594483

29 September 2017

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

1 reference

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29 September 2017

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29 September 2017

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

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29 September 2017

Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801.

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29 September 2017

Treatment of acute lymphoblastic leukemia

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29 September 2017

The 5'-nucleotidases as regulators of nucleotide and drug metabolism

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29 September 2017

Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies

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29 September 2017

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

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29 September 2017

Systemic exposure to mercaptopurine as a prognostic factor in acute lymphocytic leukemia in children.

1 reference

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2 June 2018

Relation of 5'-nucleotidase and phosphatase activities with immunophenotype, drug resistance and clinical prognosis in childhood leukemia

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2 June 2018

Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000.

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21 January 2018

Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90.

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21 January 2018

Role of 5'-nucleotidase in thiopurine metabolism: enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment

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21 January 2018

Mechanistic studies on bovine cytosolic 5'-nucleotidase II, an enzyme belonging to the HAD superfamily.

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21 January 2018

Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group

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21 January 2018

BRAF mutations in hairy-cell leukemia

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21 January 2018

Analysis of the coding genome of diffuse large B-cell lymphoma

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21 January 2018

UCSF Chimera--a visualization system for exploratory research and analysis

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21 January 2018

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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21 January 2018

I-TASSER: a unified platform for automated protein structure and function prediction

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21 January 2018

SDM--a server for predicting effects of mutations on protein stability and malfunction

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21 January 2018

Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3594483

27 November 2018

N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23377281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival after relapse in childhood acute lymphoblastic leukemia: impact of site and time to first relapse--the Children's Cancer Group Experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/23377281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23377281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NM.3078

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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ResearchGate publication ID

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