Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B (Q27675592)

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21 February 2020

title

Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B (English)

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21 February 2020

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21 February 2020

Alex MacKerell

10

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21 February 2020

author name string

E Prabhu Raman

2

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21 February 2020

Padmavani Bezawada

3

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21 February 2020

Sucheta Kudrimoti

4

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21 February 2020

Paul T Wilder

5

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21 February 2020

Kira G Hartman

6

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21 February 2020

Raquel Godoy-Ruiz

7

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21 February 2020

Eric A Toth

8

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21 February 2020

Andrew Coop

9

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21 February 2020

David J Weber

11

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21 February 2020

publication date

25 September 2012

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ACS Medicinal Chemistry Letters

21 February 2020

published in

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Crossref

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21 February 2020

volume

3

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21 February 2020

issue

12

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21 February 2020

page(s)

975-979

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Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

21 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524579

Structure of the negative regulatory domain of p53 bound to S100B(betabeta)

20 March 2017

1 reference

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Ions binding to S100 proteins. I. Calcium- and zinc-binding properties of bovine brain S100 alpha alpha, S100a (alpha beta), and S100b (beta beta) protein: Zn2+ regulates Ca2+ binding on S100b protein

20 March 2017

1 reference

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S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

20 March 2017

1 reference

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The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma

7 April 2017

1 reference

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The effect of pentamidine on melanoma ex vivo.

29 September 2017

1 reference

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Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

29 September 2017

1 reference

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Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction.

29 September 2017

1 reference

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S100 proteins as cancer biomarkers with focus on S100B in malignant melanoma

29 September 2017

1 reference

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Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells

29 September 2017

1 reference

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Concerted regulation of wild-type p53 nuclear accumulation and activation by S100B and calcium-dependent protein kinase C.

29 September 2017

1 reference

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Perspectives in S-100 protein biology. Review article

29 September 2017

1 reference

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Inhibition of p53 transcriptional activity by the S100B calcium-binding protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3524579

A soluble protein characteristic of the nervous system

2 June 2018

1 reference

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The Ca(2+)-dependent interaction of S100B(beta beta) with a peptide derived from p53

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23264854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Posttranslational modifications affect the interaction of S100 proteins with tumor suppressor p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23264854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML300166S

1 reference

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21 February 2020

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21 February 2020

PubMed publication ID

23264854

1 reference

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