Mechanism of drug inhibition and drug resistance of influenza A M2 channel (Q27655035)

20 October 2023

Jason R Schnell

series ordinal

2

author given names

Jason R

author last names

Schnell

1 reference

20 October 2023

James J Chou

series ordinal

3

author given names

James J

author last names

Chou

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 October 2023

language of work or name

English

0 references

publication date

5 May 2009

0 references

published in

0 references

volume

106

0 references

issue

18

0 references

page(s)

7379-84

0 references

cites work

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Structural basis for the function and inhibition of an influenza virus proton channel

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Structure and mechanism of the M2 proton channel of influenza A virus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

The Xplor-NIH NMR molecular structure determination package

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Proton transport through influenza A virus M2 protein reconstituted in vesicles

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Helix-packing motifs in membrane proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Influence of residue 44 on the activity of the M2 proton channel of influenza A virus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Definitive assignment of proton selectivity and attoampere unitary current to the M2 ion channel protein of influenza A virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Viral and cellular small integral membrane proteins can modify ion channels endogenous to Xenopus oocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Evolutionary analysis of the influenza A virus M gene with comparison of the M1 and M2 proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Unpacking the incoming influenza virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Functional reconstitution in lipid vesicles of influenza virus M2 protein expressed by baculovirus: evidence for proton transfer activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Antiviral agents. 2. Structure-activity relations of compounds related to 1-adamantanamine

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902548106

Helix tilt of the M2 transmembrane peptide from influenza A virus: an intrinsic property

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902548106

An in-depth analysis of the biological functional studies based on the NMR M2 channel structure of influenza A virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902548106

Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902548106

Improved sensitivity and coherence selection for [15N,1H]-TROSY elements in triple resonance experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902548106

Three-dimensional triple-resonance NMR Spectroscopy of isotopically enriched proteins. 1990.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678642

Differences in conductance of M2 proton channels of two influenza viruses at low and high pH

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19383794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0902548106

1 reference

release_c2auvspvjranto7x23zdktbegi

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c2auvspvjranto7x23zdktbegi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1760210

1 reference

1 reference

1760210

1 reference