Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics (Q27627265)

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31 October 2019

title

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics (English)

1 reference

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31 October 2019

1

1 reference

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31 October 2019

William M Clemons

2

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31 October 2019

Ditlev E. Brodersen

3

1 reference

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31 October 2019

Venkatraman Ramakrishnan

6

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31 October 2019

author name string

R J Morgan-Warren

4

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31 October 2019

B T Wimberly

5

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31 October 2019

language of work or name

English

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publication date

1 September 2000

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31 October 2019

number of pages

9

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inferred from page(s)

published in

Nature

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31 October 2019

volume

407

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31 October 2019

issue

6802

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31 October 2019

page(s)

340-348

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Ribosomes and translation

31 October 2019

cites work

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Translational accuracy and the fitness of bacteria

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Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

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7 January 2021

Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome

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7 January 2021

Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome.

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7 January 2021

Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA

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7 January 2021

The allosteric three-site model for the ribosomal elongation cycle: features and future

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Mutations in ribosomal proteins S4 and S12 influence the higher order structure of 16 S ribosomal RNA.

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A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA.

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7 January 2021

Structure of the 30S ribosomal subunit

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A new model for the three-dimensional folding of Escherichia coli 16 S ribosomal RNA. I. Fitting the RNA to a 3D electron microscopic map at 20 A.

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7 January 2021

X-ray crystal structures of 70S ribosome functional complexes

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7 January 2021

A ratchet-like inter-subunit reorganization of the ribosome during translocation

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7 January 2021

Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation

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7 January 2021

Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA.

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7 January 2021

Covalent crosslinking of tRNA1Val to 16S RNA at the ribosomal P site: identification of crosslinked residues

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7 January 2021

Identification of bases in 16S rRNA essential for tRNA binding at the 30S ribosomal P site

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7 January 2021

A new model for the three-dimensional folding of Escherichia coli 16 S ribosomal RNA. III. The topography of the functional centre.

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7 January 2021

Interaction of antibiotics with functional sites in 16S ribosomal RNA

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7 January 2021

Spectinomycin interacts specifically with the residues G1064 and C1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation

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7 January 2021

The primary structure of protein S5 from the small subunit of the Escherichia coli ribosome

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7 January 2021

Streptomycin preferentially perturbs ribosomal proofreading

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7 January 2021

Dissociation rate of cognate peptidyl-tRNA from the A-site of hyper-accurate and error-prone ribosomes

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7 January 2021

Dissociation rates of peptidyl-tRNA from the P-site of E.coli ribosomes.

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7 January 2021

Mutations in 23 S ribosomal RNA perturb transfer RNA selection and can lead to streptomycin dependence.

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7 January 2021

Cross-linking of streptomycin to the 16S ribosomal RNA of Escherichia coli

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7 January 2021

The 5' proximal helix of 16S rRNA is involved in the binding of streptomycin to the ribosome.

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7 January 2021

A mutation in the 530 loop of Escherichia coli 16S ribosomal RNA causes resistance to streptomycin

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7 January 2021

Streptomycin-resistance of Euglena gracilis chloroplasts: identification of a point mutation in the 16S rRNA gene in an invariant position

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7 January 2021

Mutations in the 915 region ofEscherichia coli16S ribosomal RNA reduce the binding of streptomycin to the ribosome

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7 January 2021

Crosslinking of streptomycin to the 30S subunit of Escherichia coli with phenyldiglyoxal

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7 January 2021

Ribosomal ambiguity (ram ) mutations facilitate dihydrostreptomycin binding to ribosomes

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7 January 2021

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

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7 January 2021

Recognition of the codon-anticodon helix by ribosomal RNA.

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Major groove binding of the tRNA/mRNA complex to the 16 S ribosomal RNA decoding site

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Identifiers

DOI

10.1038/35030019

2 references

Consolidated OpenCitations Corpus – April 2017

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Dimensions Publication ID

31 October 2019

1000509356

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

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