The architecture of a eukaryotic replisome. (Q27310198)

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28 February 2020

title

The architecture of a eukaryotic replisome (English)

1 reference

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Mini-chromosome maintenance complex protein 7 YBR202W

28 February 2020

main subject

structural biology

0 references

1 reference

MCM DNA helicase complex subunit MCM5 YLR274W

1 reference

MCM DNA helicase complex subunit MCM2 YBL023C

1 reference

MCM DNA helicase complex subunit MCM6 YGL201C

1 reference

DNA replication protein PSF3 YOL146W

1 reference

DNA replication initiation factor CDC45 YLR103C

1 reference

DNA replication protein PSF1 YDR013W

1 reference

MCM DNA helicase complex subunit MCM3 YEL032W

1 reference

DNA replication protein PSF2 YJL072C

1 reference

MCM DNA helicase complex subunit MCM4 YPR019W

1 reference

DNA replication protein SLD5 YDR489W

1 reference

author

Yi Shi

2

1 reference

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28 February 2020

Zuanning Yuan

4

1 reference

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28 February 2020

Michael O'Donnell

7

1 reference

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28 February 2020

author name string

Jingchuan Sun

1

1 reference

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28 February 2020

Roxana E Georgescu

3

1 reference

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28 February 2020

Brian T Chait

5

1 reference

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28 February 2020

Huilin Li

6

1 reference

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28 February 2020

language of work or name

English

0 references

publication date

2 November 2015

1 reference

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Nature Structural & Molecular Biology

28 February 2020

published in

1 reference

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28 February 2020

volume

22

1 reference

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28 February 2020

issue

12

1 reference

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28 February 2020

page(s)

976-982

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Structure of the eukaryotic MCM complex at 3.8 Å

28 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

DNA polymerase ε and its roles in genome stability

21 March 2017

1 reference

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A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.

21 March 2017

1 reference

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Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain

21 March 2017

1 reference

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Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ

21 March 2017

1 reference

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The minichromosome maintenance replicative helicase

21 March 2017

1 reference

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The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved

21 March 2017

1 reference

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Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta

21 March 2017

1 reference

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3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases

21 March 2017

1 reference

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Polymerase dynamics at the eukaryotic DNA replication fork

21 March 2017

1 reference

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Crystal structure of the GINS complex and functional insights into its role in DNA replication

21 March 2017

1 reference

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Yeast DNA polymerase epsilon participates in leading-strand DNA replication

21 March 2017

1 reference

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Crystal structure of the human GINS complex

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

Structure of the human GINS complex and its assembly and functional interface in replication initiation

21 March 2017

1 reference

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Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

21 March 2017

1 reference

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Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

21 March 2017

1 reference

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EMAN2: an extensible image processing suite for electron microscopy

21 March 2017

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

21 March 2017

1 reference

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Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.

21 March 2017

1 reference

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Proteomic and genomic characterization of chromatin complexes at a boundary

21 March 2017

1 reference

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Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae

21 March 2017

1 reference

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Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae

21 March 2017

1 reference

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The DNA replication fork in eukaryotic cells.

21 March 2017

1 reference

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Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

21 March 2017

1 reference

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Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes

21 March 2017

1 reference

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A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands

21 March 2017

1 reference

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The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

21 March 2017

1 reference

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Division of labor at the eukaryotic replication fork

21 March 2017

1 reference

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A third essential DNA polymerase in S. cerevisiae

21 March 2017

1 reference

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RELION: implementation of a Bayesian approach to cryo-EM structure determination

21 March 2017

1 reference

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Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.

28 September 2017

1 reference

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Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.

28 September 2017

1 reference

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Structural characterization by cross-linking reveals the detailed architecture of a coatomer-related heptameric module from the nuclear pore complex.

28 September 2017

1 reference

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DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome.

28 September 2017

1 reference

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Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.

28 September 2017

1 reference

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Interaction between human Ctf4 and the Cdc45/Mcm2-7/GINS (CMG) replicative helicase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4849863

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

28 September 2017

1 reference

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Principles and concepts of DNA replication in bacteria, archaea, and eukarya

28 September 2017

1 reference

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Replicative DNA polymerases

28 September 2017

1 reference

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Identification of cross-linked peptides from complex samples.

28 September 2017

1 reference

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Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography

28 September 2017

1 reference

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Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.

28 September 2017

1 reference

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Dividing the workload at a eukaryotic replication fork

28 September 2017

1 reference

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The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions.

28 September 2017

1 reference

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Alternate pathways of DNA replication: DNA polymerase I-dependent replication

28 September 2017

1 reference

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Bypass of a protein barrier by a replicative DNA helicase.

28 September 2017

1 reference

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Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain

31 May 2018

1 reference

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DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability

31 May 2018

1 reference

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3'-->5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae

31 May 2018

1 reference

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Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

31 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.3113

Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.3113

MCM forked substrate specificity involves dynamic interaction with the 5'-tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.3113

Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNSMB.3113

21 January 2018

Identifiers

DOI

10.1038/NSMB.3113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26524492%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 February 2020

1003825692

0 references

OpenCitations bibliographic resource ID

2524832

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2524832

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26524492%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

26524492

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26524492%20AND%20SRC:MED&resulttype=core&format=json