Gene targeting in mice: a review (Q27001077)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23996268%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Gene targeting in mice: a review (English)

1 reference

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8 March 2020

1 reference

2

1 reference

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8 March 2020

author name string

Hicham Bouabe

series ordinal

1

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23996268%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

language of work or name

1 reference

1 January 2013

1 reference

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Methods in Molecular Biology

8 March 2020

published in

2 references

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8 March 2020

volume

1064

2 references

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8 March 2020

page(s)

315-336

1 reference

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The mammalian gene function resource: the International Knockout Mouse Consortium

8 March 2020

cites work

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Cytokine reporter mice: the special case of IL-10

21 March 2017

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A conditional knockout resource for the genome-wide study of mouse gene function

21 March 2017

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Functional role of type I and type II interferons in antiviral defense

21 March 2017

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 March 2017

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21 March 2017

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Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells

21 March 2017

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Targeted oncogene activation by site-specific recombination in transgenic mice

21 March 2017

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Tissue- and site-specific DNA recombination in transgenic mice

21 March 2017

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The green fluorescent protein

21 March 2017

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Establishment in culture of pluripotential cells from mouse embryos

21 March 2017

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Recombination within the yeast plasmid 2mu circle is site-specific

21 March 2017

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 March 2017

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Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

21 March 2017

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

21 March 2017

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Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites

21 March 2017

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Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

21 March 2017

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HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

21 March 2017

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Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells

21 March 2017

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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

21 March 2017

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RAG-1-deficient mice have no mature B and T lymphocytes

21 March 2017

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 March 2017

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The ground state of embryonic stem cell self-renewal

21 March 2017

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

7 April 2017

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

7 April 2017

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

7 April 2017

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Control of the embryonic stem cell state

7 April 2017

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Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

7 April 2017

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

7 April 2017

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

7 April 2017

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The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

7 April 2017

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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

7 April 2017

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Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

7 April 2017

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The mouse genome database: genotypes, phenotypes, and models of human disease

7 April 2017

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C-type lectin receptors orchestrate antifungal immunity

28 September 2017

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Resisting viral infection: the gene by gene approach

28 September 2017

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A resource of vectors and ES cells for targeted deletion of microRNAs in mice.

28 September 2017

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Recent developments of biological reporter technology for detecting gene expression

28 September 2017

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Cytokine reporter mice in immunological research: perspectives and lessons learned

28 September 2017

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Activation of host pattern recognition receptors by viruses.

28 September 2017

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Bioluminescence imaging of reporter mice for studies of infection and inflammation

28 September 2017

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Function of the nucleotide exchange activity of vav1 in T cell development and activation

28 September 2017

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Generation of gene knockout mice by ES cell microinjection

28 September 2017

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Novel reporter mouse reveals constitutive and inflammatory expression of IFN-beta in vivo

28 September 2017

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Agouti C57BL/6N embryonic stem cells for mouse genetic resources

28 September 2017

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Generation of chimeras by microinjection

28 September 2017

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Overview of gene targeting by homologous recombination

28 September 2017

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Lymphocyte signaling: beyond knockouts.

28 September 2017

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The roles of TLRs, RLRs and NLRs in pathogen recognition

28 September 2017

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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.

28 September 2017

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Laminin-511 but not -332, -111, or -411 enables mouse embryonic stem cell self-renewal in vitro

28 September 2017

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Embryonic stem cells derived from C57BL/6J and C57BL/6N mice

28 September 2017

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Overview of genetic reporter systems

28 September 2017

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Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line

28 September 2017

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Derivation and comparison of C57BL/6 embryonic stem cells to a widely used 129 embryonic stem cell line

28 September 2017

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Beta-lactamase: an ideal reporter system for monitoring gene expression in live eukaryotic cells

28 September 2017

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Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions.

28 September 2017

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Technical assessment of the first 20 years of research using mouse embryonic stem cell lines

28 September 2017

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Realization of beta-lactamase as a versatile fluorogenic reporter.

28 September 2017

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To knockout in 129 or in C57BL/6: that is the question

28 September 2017

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Transgenic mouse with the herpes simplex virus type 1 latency-associated gene: expression and function of the transgene

28 September 2017

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Recent advances in inducible expression in transgenic mice

28 September 2017

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The 2.2-kilobase latency-associated transcript of herpes simplex virus type 2 does not modulate viral replication, reactivation, or establishment of latency in transgenic mice

28 September 2017

1 reference

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The application of transgenic and knockout mouse technology for the study of viral pathogenesis

28 September 2017

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Functional roles of STAT family proteins: lessons from knockout mice

28 September 2017

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Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

28 September 2017

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Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells

28 September 2017

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Different thermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination

28 September 2017

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Long-range disruption of gene expression by a selectable marker cassette

28 September 2017

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Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

28 September 2017

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Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

28 September 2017

1 reference

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Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice.

28 September 2017

1 reference

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A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses

28 September 2017

1 reference

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P1 site-specific recombination: nucleotide sequence of the recombining sites

28 September 2017

1 reference

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Introduction of a rabbit beta-globin gene into the mouse germ line

28 September 2017

1 reference

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Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules

28 September 2017

1 reference

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Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs

28 September 2017

1 reference

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The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

28 September 2017

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Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

28 September 2017

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High frequency targeting of genes to specific sites in the mammalian genome

28 September 2017

1 reference

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The FLP recombinase of the yeast 2-micron plasmid: characterization of its recombination site

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Establishment of a germ-line competent C57BL/6 embryonic stem cell line

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

The length of homology required for gene targeting in embryonic stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Reexamination of Gene Targeting Frequency as a Function of the Extent of Homology between the Targeting Vector and the Target Locus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Novel highly sensitive IL-10-beta-lactamase reporter mouse reveals cells of the innate immune system as a substantial source of IL-10 in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Improved properties of FLP recombinase evolved by cycling mutagenesis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Cellular mechanisms involved in protection against influenza virus infection in transgenic mice expressing a TCR receptor specific for class II hemagglutinin peptide in CD4+ and CD8+ T cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

The FLP recombinase of the 2 micron circle DNA of yeast: interaction with its target sequences

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Generation of chimeras by morula aggregation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Lineage-specific requirement for the PH domain of Vav1 in the activation of CD4+ but not CD8+ T cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524968

Analysis of Homologous Recombination in Cultured Mammalian Cells

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Bacteriophage P1 Cre-loxP site-specific recombination. Site-specific DNA topoisomerase activity of the Cre recombination protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Homologous integration in mammalian cells without target gene selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Chemiluminescence: sensitive detection technology for reporter gene assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Chemiluminescent immunoassay for the detection of chloramphenicol acetyltransferase and human growth hormone reporter proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

Enhanced selection for homologous-recombinant embryonic stem cell clones by Cre recombinase-mediated deletion of the positive selection marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/23996268

12 December 2020

10.1007/978-1-62703-601-6_23

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23996268%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23996268%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

2 references