GRK2 in the heart: a GPCR kinase and beyond (Q26851548)

G protein-coupled receptor

main subject

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2

Erhe Gao

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author name string

Zheng Maggie Huang

series ordinal

1

1 reference

Crossref

J. Kurt Chuprun

series ordinal

3

1 reference

Crossref

Walter J. Koch

series ordinal

4

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Crossref

language of work or name

1 reference

10 November 2014

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Antioxidants & Redox Signaling

published in

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volume

21

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issue

14

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page(s)

2032-43

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Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts

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Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

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Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility

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Regulation of G protein-coupled receptor kinases by caveolin

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Combination of isosorbide dinitrate and hydralazine in blacks with heart failure

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Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein

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Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

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Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

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Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury

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Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2

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Inhibition of G protein-coupled receptor kinase subtypes by Ca2+/calmodulin

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Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process

7 April 2017

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Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase

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Importance of myocyte-nonmyocyte interactions in cardiac development and disease

28 September 2017

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AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model

28 September 2017

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Beta3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation

28 September 2017

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G protein-coupled receptor kinases in normal and failing myocardium

28 September 2017

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Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

28 September 2017

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Exercise protects against myocardial ischemia-reperfusion injury via stimulation of β(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols

28 September 2017

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G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.

28 September 2017

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G protein-coupled receptor kinase-2 is a novel regulator of collagen synthesis in adult human cardiac fibroblasts

28 September 2017

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Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

28 September 2017

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Comparative cardiac gene delivery of adeno-associated virus serotypes 1-9 reveals that AAV6 mediates the most efficient transduction in mouse heart

28 September 2017

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Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure

28 September 2017

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G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.

28 September 2017

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G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression

28 September 2017

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Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload

28 September 2017

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Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

28 September 2017

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S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking

28 September 2017

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G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

28 September 2017

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Gene therapy in heart failure

28 September 2017

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A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

28 September 2017

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Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK.

28 September 2017

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Cardiac adrenoceptors: physiological and pathophysiological relevance

28 September 2017

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Nitric oxide regulates endocytosis by S-nitrosylation of dynamin

28 September 2017

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A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.

28 September 2017

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The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction

28 September 2017

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Oxygen, oxidative stress, hypoxia, and heart failure

28 September 2017

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G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence

28 September 2017

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Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases

28 September 2017

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Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin

28 September 2017

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G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits.

28 September 2017

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Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure

28 September 2017

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Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.

28 September 2017

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Reactive oxygen species mediate alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes

28 September 2017

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Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.

28 September 2017

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Reactive oxygen species, cell signaling, and cell injury

28 September 2017

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beta-adrenergic receptor blockade in chronic heart failure

28 September 2017

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Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases.

28 September 2017

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Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

28 September 2017

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The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.

28 September 2017

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Dynamic activation of endothelial nitric oxide synthase by Hsp90.

28 September 2017

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The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin

28 September 2017

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Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer

28 September 2017

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MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure

28 September 2017

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Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice

28 September 2017

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Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

28 September 2017

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Structure and mechanism of the G protein-coupled receptor kinases.

28 September 2017

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Turning off the signal: desensitization of beta-adrenergic receptor function

28 September 2017

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Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

28 September 2017

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Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

28 September 2017

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Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting

28 September 2017

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The beta(2)-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 3'-kinase

31 May 2018

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Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaq

31 May 2018

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Mechanisms of impaired beta-adrenergic receptor signaling in G(alphaq)-mediated cardiac hypertrophy and ventricular dysfunction

31 May 2018

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade

31 May 2018

1 reference

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Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase

31 May 2018

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The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

31 May 2018

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Phosphorylation and Activation of β-Adrenergic Receptor Kinase by Protein Kinase C

31 May 2018

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A direct test of the hypothesis that increased microtubule network density contributes to contractile dysfunction of the hypertrophied heart.

31 May 2018

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Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling.

28 November 2018

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Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

28 November 2018

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Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex

28 November 2018

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Level of beta-adrenergic receptor kinase 1 inhibition determines degree of cardiac dysfunction after chronic pressure overload-induced heart failure

28 November 2018

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Nitroso-redox balance in the cardiovascular system

28 November 2018

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Cardiac hypertrophy and altered beta-adrenergic signaling in transgenic mice that express the amino terminus of beta-ARK1.

28 November 2018

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Regulation of the inward rectifying properties of G-protein-activated inwardly rectifying K+ (GIRK) channels by Gbeta gamma subunits

28 November 2018

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Expression of a beta-adrenergic receptor kinase inhibitor reverses dysfunction in failing cardiomyocytes

28 November 2018

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Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene transfer of a beta-adrenergic receptor kinase inhibitor

28 November 2018

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Molecular beta-adrenergic signaling abnormalities in failing rabbit hearts after infarction

28 November 2018

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12 December 2020

Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium

1 reference

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12 December 2020

Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility

1 reference

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12 December 2020

Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy

1 reference

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12 December 2020

Physiological induction of a beta-adrenergic receptor kinase inhibitor transgene preserves ss-adrenergic responsiveness in pressure-overload cardiac hypertrophy

1 reference

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12 December 2020

RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice

1 reference

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12 December 2020

A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the beta 2-adrenergic receptor

1 reference

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12 December 2020

Activation of beta-adrenergic receptor kinase during myocardial ischemia

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12 December 2020

Novel myofilament Ca2+-sensitizing property of xanthine oxidase inhibitors

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12 December 2020

G protein-coupled receptor kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24702056

12 December 2020

Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds

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12 December 2020

Identifiers

DOI

10.1089/ARS.2014.5876

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5024850

OpenCitations bibliographic resource ID

5024850

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

PubMed publication ID

24702056

1 reference