Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain (Q24676619)

1

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B Laffert

2

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G R Screaton

3

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M Kraft

4

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D Wolf

5

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W Kolanus

6

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J Mongkolsapay

7

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A J McMichael

8

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A S Baur

Journal of Experimental Medicine

9

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language of work or name

English

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publication date

3 May 1999

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published in

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volume

189

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issue

9

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page(s)

1489-96

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cites work

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2

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Role of the Fas/Fas ligand pathway in apoptotic cell death induced by the human T cell lymphotropic virus type I Tax transactivator

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Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus

28 September 2017

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Interleukin-1 beta converting enzyme-like protease involvement in Fas-induced and activation-induced peripheral blood T cell apoptosis in HIV infection. TNF-related apoptosis-inducing ligand can mediate activation-induced T cell death in HIV infecti

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Upregulation of Fas ligand by simian immunodeficiency virus - a nef-arious mechanism of immune evasion?

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CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

28 September 2017

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Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

28 September 2017

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Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals.

28 September 2017

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TCR/CD3 coupling to Fas-based cytotoxicity

28 September 2017

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Metalloproteinase-mediated release of human Fas ligand

28 September 2017

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Molecular and genetic insights into T cell antigen receptor structure and function

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Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

28 September 2017

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Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

28 September 2017

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Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14.

28 September 2017

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Elevated serum level of Fas ligand correlates with the asymptomatic stage of human immunodeficiency virus infection

30 May 2018

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HIV-1 upregulates Fas ligand expression in CD4+ T cells in vitro and in vivo: association with Fas-mediated apoptosis and modulation by aurintricarboxylic acid

30 May 2018

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Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

30 May 2018

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The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

30 May 2018

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Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain

30 May 2018

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Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

30 May 2018

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HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

28 November 2018

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A cysteine protease inhibitor prevents activation-induced T-cell apoptosis and death of peripheral blood cells from human immunodeficiency virus-infected individuals by inhibiting upregulation of Fas ligand.

28 November 2018

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Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

28 November 2018

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The N-Terminus of Nef from HIV-1/SIV Associates with a Protein Complex Containing Lck and a Serine Kinase

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

HIV-induced immunopathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

Programmed death of T cells in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

A role for CD95 ligand in preventing graft rejection

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https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

1 reference

https://pubmed.ncbi.nlm.nih.gov/10224289

12 December 2020

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

1 reference

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12 December 2020

release_4dlludlwvzahdmzl7cuwtisbii

Identifiers

DOI

10.1084/JEM.189.9.1489

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4dlludlwvzahdmzl7cuwtisbii

24 November 2022