p63 regulates proliferation and differentiation of developmentally mature keratinocytes (Q24675193)

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22 December 2019

title

p63 regulates proliferation and differentiation of developmentally mature keratinocytes (English)

1 reference

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22 December 2019

1 reference

4

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22 December 2019

author name string

Amy B Truong

1

1 reference

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22 December 2019

Markus Kretz

2

1 reference

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22 December 2019

Todd W Ridky

3

1 reference

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22 December 2019

Paul A Khavari

5

1 reference

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22 December 2019

language of work or name

English

0 references

publication date

1 November 2006

1 reference

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22 December 2019

1 reference

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22 December 2019

volume

20

1 reference

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22 December 2019

issue

22

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22 December 2019

page(s)

3185-3197

1 reference

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Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains

22 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

The p53 family member genes are involved in the Notch signal pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 is the molecular switch for initiation of an epithelial stratification program

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 is a p53 homologue required for limb and epidermal morphogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 regulates an adhesion programme and cell survival in epithelial cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Differential recognition of response elements determines target gene specificity for p53 and p63

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p63 and the epithelial stem cell: more than status quo?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Impact of Bcl-2 and Ha-ras on keratinocytes in organotypic culture

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

28 September 2017

Epidermal cell lineage

1 reference

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Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Methods for Cultivation of Keratinocytes with an Air-Liquid Interface

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Perp is a p63-regulated gene essential for epithelial integrity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

A dominant-negative form of p63 is required for epidermal proliferation in zebrafish.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Expression of keratins in normal, immortalized and malignant oral epithelia in organotypic culture.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635152

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17114587

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17114587

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1463206

2 references

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22 December 2019

1 reference

2 references

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22 December 2019

PubMed publication ID

17114587

2 references