The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease (Q24656574)

41

0 references

Gerold Schmitt-Ulms

37

0 references

Olav M. Andersen

Olav M Andersen

30

0 references

Rivka Inzelberg

Rivka Inzelberg

26

0 references

Thomas E Willnow

Thomas E Willnow

31

0 references

Clinton Baldwin

Clinton T Baldwin

8

0 references

Joseph H. Lee

Joseph H Lee

3

0 references

Kathryn L. Lunetta

Kathryn L Lunetta

13

0 references

Sandro Sorbi

Sandro Sorbi

22

0 references

Lindsay A. Farrer

Lindsay A Farrer

40

0 references

Dennis W. Dickson

Dennis Dickson

34

0 references

Robert C. Green

19

Robert C Green

0 references

Richard Mayeux

39

Richard Mayeux

0 references

Toshitaka Kawarai

5

Toshitaka Kawarai

0 references

Ronald C. Petersen

33

Ronald C Petersen

0 references

L. Adrienne Cupples

17

L Adrienne Cupples

0 references

Neill R Graff-Radford

32

Neill Graff-Radford

0 references

Amalia Bruni

23

Amalia Bruni

0 references

Innocenzo Rainero

21

Innocenzo Rainero

0 references

Lorenzo Pinessi

20

Lorenzo Pinessi

0 references

Yosuke Wakutani

16

Yosuke Wakutani

0 references

Christopher Bohm

15

Christopher Bohm

0 references

Taiichi Katayama

7

Taiichi Katayama

0 references

Nobuto Shibata

12

Nobuto Shibata

0 references

Ranjan Duara

24

Ranjan Duara

0 references

Fanggeng Zou

6

Fanggeng Zou

0 references

Robert P Friedland

25

Robert P Friedland

0 references

You-Qiang Song

29

You-Qiang Song

0 references

Steven G. Younkin

38

Steven Younkin

0 references

author name string

Yan Meng

2

0 references

Yongjun Gu

4

0 references

Rong Cheng

9

0 references

Hiroshi Hasegawa

10

0 references

Fusheng Chen

11

0 references

Raphaelle Pardossi-Piquard

14

0 references

Karen T Cuenco

18

0 references

Wolfgang Hampe

27

0 references

Hideaki Bujo

28

0 references

Sandy D Der

35

0 references

Paul E Fraser

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

36

0 references

language of work or name

English

0 references

publication date

February 2007

0 references

published in

Nature Genetics

0 references

volume

39

0 references

issue

2

0 references

page(s)

168-77

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Pathways towards and away from Alzheimer's disease

7 April 2017

1 reference

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Are rare variants responsible for susceptibility to complex diseases?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Schizophrenia: genes at last?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Recycle your receptors with retromer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Loss of apolipoprotein E receptor LR11 in Alzheimer disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Spatial segregation of gamma-secretase and substrates in distinct membrane domains

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Score tests for association between traits and haplotypes when linkage phase is ambiguous

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Model-guided microarray implicates the retromer complex in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Current status of genetics research in inflammatory bowel disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Genomic screening and replication using the same data set in family-based association testing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

The presenilin proteins are components of multiple membrane-bound complexes that have different biological activities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

The allelic architecture of human disease genes: common disease-common variant... or not?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Power calculations for a general class of family-based association tests: dichotomous traits

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Risk of dementia among white and African American relatives of patients with Alzheimer disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Nicastrin binds to membrane-tethered Notch

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

GGA proteins mediate the recycling pathway of memapsin 2 (BACE).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

PBAT: tools for family-based association studies

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

A multivariate family-based association test using generalized estimating equations: FBAT-GEE.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Improved use of SNP information to detect the role of genes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Association between apolipoprotein E genotype and Alzheimer disease in African American subjects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Prevalence of Alzheimer's type dementia in an elderly Arab population.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2657343

Linkage disequilibrium mapping of complex disease: fantasy or reality?

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17220890

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG1943

1 reference

Dimensions Publication ID

1004831996

0 references

1 reference

1 reference

PubMed publication ID

17220890

1 reference