Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs) (Q24650602)

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English	Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)	scientific article

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scholarly article

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Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs) (English)

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P. Jeffrey Conn

7

object named as

P Jeffrey Conn

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Colleen M. Niswender

2

object named as

Colleen M Niswender

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Craig W. Lindsley

8

object named as

Craig W Lindsley

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5

object named as

Usha N Menon

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Corey R. Hopkins

9

object named as

Corey R Hopkins

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Darren W. Engers

1

object named as

Darren W Engers

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6

object named as

Rocio Zamorano

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author name string

C David Weaver

3

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Satyawan Jadhav

4

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language of work or name

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publication date

23 July 2009

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Journal of Medicinal Chemistry

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52

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14

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4115-8

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Ligand efficiency: a useful metric for lead selection

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Pharmacology and functions of metabotropic glutamate receptors

1 reference

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

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Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse.

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Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

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28 November 2018

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10.1021/JM9005065

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