Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation (Q24642681)

Gene Ontology release 2020-05-02

7

Christopher K Glass

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author name string

Wenlai Zhou

1

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Ping Zhu

2

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Jianxun Wang

3

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Gabriel Pascual

4

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Kenneth A Ohgi

5

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Jean Lozach

6

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Michael G Rosenfeld

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation

8

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language of work or name

English

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publication date

18 January 2008

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published in

Molecular Cell

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volume

29

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issue

1

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page(s)

69-80

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cites work

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Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II

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Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

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A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.

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7 April 2017

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Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

7 April 2017

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A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

7 April 2017

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Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway

7 April 2017

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7 April 2017

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7 April 2017

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Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

7 April 2017

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7 April 2017

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Rad6-dependent ubiquitination of histone H2B in yeast

7 April 2017

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7 April 2017

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Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation

7 April 2017

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Breaking barriers to transcription elongation

27 September 2017

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de FACTo nucleosome dynamics

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The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

27 September 2017

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Leaving a mark: the many footprints of the elongating RNA polymerase II.

27 September 2017

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The key to development: interpreting the histone code?

27 September 2017

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The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.

27 September 2017

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A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

27 September 2017

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H2B ubiquitylation: the end is in sight

27 September 2017

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Transcriptional regulation by histone ubiquitination and deubiquitination.

27 September 2017

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IRF3 mediates a TLR3/TLR4-specific antiviral gene program

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The structure of ubiquitinated histone H2B.

27 September 2017

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The active immunoglobulin kappa chain gene is packaged by non-ubiquitin-conjugated nucleosomes

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Ubiquitinated histone H2B is preferentially located in transcriptionally active chromatin

27 September 2017

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Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the drosophila genome

27 September 2017

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Enrichment of ubiquitinated histone H2A in a low salt extract of micrococcal nuclease-digested myotube nuclei.

30 May 2018

1 reference

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Affinity isolation of active murine erythroleukemia cell chromatin: Uniform distribution of ubiquitinated histone H2A between active and inactive fractions

30 May 2018

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The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II.

30 May 2018

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Polycomb silencing blocks transcription initiation.

28 November 2018

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Binary switches and modification cassettes in histone biology and beyond.

28 November 2018

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A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.

28 November 2018

1 reference

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General transcription factors bind promoters repressed by Polycomb group proteins.

28 November 2018

1 reference

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Nucleosomes can form a polar barrier to transcript elongation by RNA polymerase II

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18206970

12 December 2020

Isolation and characterization of protein A24, a "histone-like" non-histone chromosomal protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/18206970

12 December 2020

Structure of polyubiquitinated histone H2A

1 reference

https://pubmed.ncbi.nlm.nih.gov/18206970

12 December 2020

Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18206970

12 December 2020

Nature of the nucleosomal barrier to RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/18206970

12 December 2020

10.1016/J.MOLCEL.2007.11.002

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

18206970

1 reference