The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression (Q24630336)

1

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Masayuki Iwasaki

2

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Francesca Ficara

4

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Christine Carico

5

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Christopher Arnold

6

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Chang-Zheng Chen

7

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Michael L Cleary

miR-19 is a key oncogenic component of mir-17-92

8

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language of work or name

English

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publication date

1 May 2010

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published in

Cancer Research

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volume

70

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issue

9

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page(s)

3833-42

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cites work

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Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas

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Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

7 April 2017

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Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

7 April 2017

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Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

7 April 2017

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Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

7 April 2017

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MicroRNA targeting specificity in mammals: determinants beyond seed pairing

7 April 2017

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MicroRNA fingerprints during human megakaryocytopoiesis

7 April 2017

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miR-15 and miR-16 induce apoptosis by targeting BCL2

7 April 2017

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c-Myc-regulated microRNAs modulate E2F1 expression

7 April 2017

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A microRNA polycistron as a potential human oncogene

7 April 2017

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

7 April 2017

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MicroRNAs modulate hematopoietic lineage differentiation

7 April 2017

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

7 April 2017

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MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

7 April 2017

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Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells

7 April 2017

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Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster

7 April 2017

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Phylogenetic shadowing and computational identification of human microRNA genes

7 April 2017

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The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

7 April 2017

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Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice

7 April 2017

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Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

7 April 2017

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Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias

27 September 2017

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MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

27 September 2017

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Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

27 September 2017

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The microRNAs involved in human myeloid differentiation and myelogenous/myeloblastic leukemia

27 September 2017

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MicroRNAs in normal and malignant hematopoiesis

27 September 2017

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MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression

27 September 2017

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Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

27 September 2017

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OncomiRs: the discovery and progress of microRNAs in cancers

27 September 2017

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An E2F/miR-20a autoregulatory feedback loop.

27 September 2017

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

27 September 2017

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Multiple mixed lineage leukemia (MLL) fusion proteins suppress p53-mediated response to DNA damage

27 September 2017

1 reference

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27 September 2017

1 reference

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

27 September 2017

1 reference

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p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.

27 September 2017

1 reference

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27 September 2017

1 reference

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Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2862107

MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2862107

MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2862107

MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20406979

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-09-3268

1 reference

1 reference

1 reference

PubMed publication ID

20406979

1 reference