Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke (Q24623219)

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27 December 2019

title

Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke (English)

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27 December 2019

0 references

3

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27 December 2019

Peter J. Crack

4

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27 December 2019

author name string

Katrina L Scarff

1

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27 December 2019

Kheng S Ung

2

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27 December 2019

Catherina H Bird

5

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27 December 2019

Phillip I Bird

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27 December 2019

language of work or name

English

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publication date

1 May 2004

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Molecular and Cellular Biology

27 December 2019

published in

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27 December 2019

volume

24

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27 December 2019

issue

9

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27 December 2019

page(s)

4075-4082

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Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif

27 December 2019

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Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1

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Structure of a serpin-protease complex shows inhibition by deformation

7 April 2017

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The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency

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Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1)

7 April 2017

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Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction

7 April 2017

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Abnormalities of synapses and neurons in the hippocampus of neuropsin-deficient mice

7 April 2017

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Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

7 April 2017

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The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

7 April 2017

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A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

7 April 2017

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NFkappaB-dependent signaling pathways

7 April 2017

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Mutations in the neutrophil elastase gene in cyclic and congenital neutropenia

27 September 2017

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Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

27 September 2017

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Human monocyte/neutrophil elastase inhibitor (MNEI) is regulated by PU.1/Spi-1, Sp1, and NF-kappaB.

27 September 2017

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Modulation of neutrophil function in host defense against disseminated Candida albicans infection in mice

27 September 2017

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Regulation of pro-apoptotic leucocyte granule serine proteinases by intracellular serpins.

27 September 2017

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The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G.

27 September 2017

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Non-serum-dependent chemotactic factors produced by Candida albicans stimulate chemotaxis by binding to the formyl peptide receptor on neutrophils and to an unknown receptor on macrophages

27 September 2017

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Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway

27 September 2017

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Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Proteinase inhibitor 6 cannot be secreted, which suggests it is a new type of cellular serpin

27 September 2017

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27 September 2017

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Characterization of cytoplasmic secretory granules (PSG), in prostatic epithelium and their transformation-induced loss in dysplasia and adenocarcinoma.

30 May 2018

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Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity

30 May 2018

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30 May 2018

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A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice

30 May 2018

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Concanavalin A enhances phagocytosis and killing of Candida albicans by mice peritoneal neutrophils and macrophages

28 November 2018

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Neuroserpin, a neuroprotective factor in focal ischemic stroke

28 November 2018

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Comparison of Human Chromosome 6p25 with Mouse Chromosome 13 Reveals a Greatly Expanded Ov-Serpin Gene Repertoire in the Mouse

28 November 2018

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Expression of the kallikrein gene family in normal and Alzheimer's disease brain

28 November 2018

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Serine proteinase inhibitor 3 and murinoglobulin I are potent inhibitors of neuropsin in adult mouse brain

28 November 2018

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Human Ovalbumin Serpin Evolution: Phylogenic Analysis, Gene Organization, and Identification of New PI8-Related Genes Suggest That Two Interchromosomal and Several Intrachromosomal Duplications Generated the Gene Clusters at 18q21–q23 and 6p25

28 November 2018

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The expression and localization of serine proteinase inhibitor PI-6 mRNA in developmental and ischemic mouse brain

28 November 2018

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Resistance of SCID mice to Candida albicans administered intravenously or colonizing the gut: role of polymorphonuclear leukocytes and macrophages.

28 November 2018

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Phagocytosis and intracellular killing of Candida albicans blastoconidia by neutrophils and macrophages: a comparison of different microbiological test systems

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15082799

12 December 2020

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15082799

12 December 2020

Distribution of serine proteinase inhibitor, clade B, member 6 (Serpinb6) in the adult mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15082799

12 December 2020

Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15082799

12 December 2020

10.1128/MCB.24.9.4075-4082.2004

Identifiers

DOI

1 reference

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27 December 2019

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27 December 2019

PubMed publication ID

15082799

1 reference