Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis (Q24608039)

8

object named as

Gabriele Bergers

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author name string

Marta Pàez-Ribes

1

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Elizabeth Allen

2

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James Hudock

3

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Takaaki Takeda

4

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Hiroaki Okuyama

5

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Francesc Viñals

6

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Masahiro Inoue

7

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Douglas Hanahan

Modes of resistance to anti-angiogenic therapy

9

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language of work or name

English

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publication date

3 March 2009

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published in

Cancer Cell

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volume

15

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issue

3

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page(s)

220-31

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cites work

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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

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Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

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Angiogenesis: an organizing principle for drug discovery?

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Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

7 April 2017

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VEGF Trap induces antiglioma effect at different stages of disease

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HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

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Loss of vascular endothelial growth factor expression reduces vascularization, but not growth, of tumors lacking the Von Hippel-Lindau tumor suppressor gene.

27 September 2017

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AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

27 September 2017

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Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation

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Can tumor angiogenesis be inhibited without resistance?

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Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches.

27 September 2017

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Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption

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27 September 2017

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Antiangiogenic therapy of transgenic mice impairs de novo tumor growth

27 September 2017

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Inhibition of angiogenesis

27 September 2017

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Pericytes limit tumor cell metastasis

27 September 2017

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Effects of reoxygenation on cells from hypoxic regions of solid tumors: anticancer drug sensitivity and metastatic potential.

30 May 2018

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A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.

28 November 2018

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28 November 2018

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Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma

28 November 2018

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VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

28 November 2018

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Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis

28 November 2018

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Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2.

28 November 2018

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Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

28 November 2018

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Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249680

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/19249680

1 reference

12 December 2020

Occult central nervous system involvement in patients with metastatic breast cancer: prevalence, predictive factors and impact on overall survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249680

12 December 2020

The value of immunohistochemistry for collagen IV expression in colorectal carcinomas

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https://pubmed.ncbi.nlm.nih.gov/19249680

12 December 2020

Halting angiogenesis suppresses carcinoma cell invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249680

12 December 2020

Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19249680

12 December 2020

10.1016/J.CCR.2009.01.027

Identifiers

DOI

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release_fhgg2hko4jbkfkov4fvkihzu6y

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/fhgg2hko4jbkfkov4fvkihzu6y

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

19249680

1 reference