The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer (Q24564355)

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English	The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer	scientific article

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The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer (English)

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based on heuristic

inferred from title

pancreatic carcinoma

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based on heuristic

inferred from title

heparan sulfate proteoglycans

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based on heuristic

inferred from title

Markus Büchler

5

object named as

M W Büchler

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4

object named as

H Friess

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author name string

J Kleeff

1

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T Ishiwata

2

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A Kumbasar

3

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A D Lander

6

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M Korc

7

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language of work or name

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publication date

1 November 1998

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Journal of Clinical Investigation

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102

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9

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1662-73

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Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Cerebroglycan, a developmentally regulated cell-surface heparan sulfate proteoglycan, is expressed on developing axons and growth cones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Integral membrane heparan sulfate proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

24 March 2017

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

7 April 2017

Heparin-binding EGF-like growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

A rapid quantitative assay for the detection of mammalian heparanase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Identification of glypican as a dual modulator of the biological activity of fibroblast growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

cDNA cloning, genomic organization, and in vivo expression of rat N-syndecan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Syndecan-1 alterations during the tumorigenic progression of human colonic Caco-2 cells induced by human Ha-ras or polyoma middle T oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Induction and expression of heparin-binding EGF-like growth factor in human pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Association between syndecan-1 expression and clinical outcome in squamous cell carcinoma of the head and neck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Membrane anchoring of heparan sulfate proteoglycans by phosphatidylinositol and kinetics of synthesis of peripheral and detergent-solubilized proteoglycans in Schwann cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Chronic pancreatitis: evolution of the disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

The type 1 (EGFR-related) family of growth factor receptors and their ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Heparin-binding EGF-like growth factor is an autocrine growth factor for rat gastric epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Heparan sulfate-mediated cell aggregation. Syndecans-1 and -4 mediate intercellular adhesion following their transfection into human B lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Regulation by heparan sulfate in fibroblast growth factor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Sorting and intracellular trafficking of a glycosylphosphatidylinositol-anchored protein and two hybrid transmembrane proteins with the same ectodomain in Madin-Darby canine kidney epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

27 September 2017

Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Large scale deletions in the GPC3 gene may account for a minority of cases of Simpson-Golabi-Behmel syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms. Heparan sulfate glycosaminoglycan requirement for Met binding and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Interactions between the Flk-1 receptor, vascular endothelial growth factor, and cell surface proteoglycan identified with a soluble receptor reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

A diverse set of developmentally regulated proteoglycans is expressed in the rat central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Relationships between heparanase activity and increasing metastatic potential of fibroblasts transfected with various oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Tumor necrosis factor up-regulates gamma-interferon binding in a human carcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Production of heparanase by normal and neoplastic murine B-lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

30 May 2018

Developmental and cell-type-specific expression of cell surface heparan sulfate proteoglycans in the rat heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

28 November 2018

Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

28 November 2018

Induction and expression of amphiregulin in human pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

28 November 2018

Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

28 November 2018

Binding of heparan sulfate to type V collagen. A mechanism of cell-substrate adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=509114

28 November 2018

Pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

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Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparan sulfate proteoglycans are required for mesoderm formation in Xenopus embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential markers (enzymes, proteoglycans) for human liver tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of heparan sulfate in the terminal differentiation of growth plate chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased Mitogenic Response to Heparin-Binding Epidermal Growth Factor–like Growth Factor in Vascular Smooth Muscle Cells of Diabetic Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

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Heparan sulfate proteoglycans play a dual role in regulating fibroblast growth factor-2 mitogenic activity in human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human prostate carcinoma cells produce extracellular heparanase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparan sulfate proteoglycan expression in human lung-cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

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The cell surface proteoglycan syndecan-1 mediates fibroblast growth factor-2 binding and activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycosaminoglycans of Human Prostatic Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycosaminoglycans of human bladder cancers of varying grade and stage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9802880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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