Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling (Q24537487)

6 July 2017

title

Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling (English)

1 reference

6 July 2017

0 references

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GOA release 2020-03-11

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Michael P Loreto

1

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6 July 2017

Donna M Berry

series ordinal

2

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6 July 2017

C Jane McGlade

series ordinal

3

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6 July 2017

language of work or name

English

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publication date

1 June 2002

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Molecular and Cellular Biology

6 July 2017

published in

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6 July 2017

volume

22

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6 July 2017

issue

12

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6 July 2017

page(s)

4241-4255

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Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling

6 July 2017

cites work

1 reference

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Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2-interacting transmembrane adaptor protein)

24 March 2017

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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

24 March 2017

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Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

24 March 2017

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SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling

24 March 2017

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APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis

24 March 2017

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Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

24 March 2017

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

24 March 2017

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Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase

24 March 2017

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

24 March 2017

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24 March 2017

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Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

27 September 2017

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Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

24 March 2017

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The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

24 March 2017

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The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

24 March 2017

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Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

24 March 2017

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Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

24 March 2017

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The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor

24 March 2017

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CSK: a protein-tyrosine kinase involved in regulation of src family kinases

24 March 2017

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T cell antigen-receptor signal transduction

24 March 2017

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Adaptors and molecular scaffolds in immune cell signaling

24 March 2017

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Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

24 March 2017

1 reference

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

24 March 2017

1 reference

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

7 April 2017

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Signal transduction by lymphocyte antigen receptors

7 April 2017

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A new ticket for entry into budding vesicles-ubiquitin

7 April 2017

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Adapters in lymphocyte signalling

27 September 2017

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Proximal protein tyrosine kinases in immunoreceptor signaling

27 September 2017

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Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.

27 September 2017

1 reference

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Caspase-dependent cleavage of the hematopoietic specific adaptor protein Gads alters signalling from the T cell receptor

27 September 2017

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Cbl: many adaptations to regulate protein tyrosine kinases

27 September 2017

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On the dynamics of TCR:CD3 complex cell surface expression and downmodulation

27 September 2017

1 reference

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Internalization and intracellular fate of TCR-CD3 complexes

27 September 2017

1 reference

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Lymphocyte signaling: Cbl sets the threshold for autoimmunity

27 September 2017

1 reference

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The linker phosphorylation site Tyr292 mediates the negative regulatory effect of Cbl on ZAP-70 in T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

Slap negatively regulates Src mitogenic function but does not revert Src-induced cell morphology changes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells

27 September 2017

1 reference

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The Cbl protooncoprotein: a negative regulator of immune receptor signal transduction

27 September 2017

1 reference

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Integration of T cell receptor-dependent signaling pathways by adapter proteins

27 September 2017

1 reference

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Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

T cell antigen receptor signal transduction pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

Suppression of apoptosis and granulocyte colony-stimulating factor-induced differentiation by an oncogenic form of Cbl.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor

30 May 2018

1 reference

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The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain

30 May 2018

1 reference

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Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133880

The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12024036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12024036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12024036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.22.12.4241-4255.2002

1 reference

release_2v2ny6wqqnbxvhfdppjdji6i4u

6 July 2017

Fatcat ID

0 references

PMC publication ID

133880

1 reference

6 July 2017

1 reference