UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia (Q24533339)

19 October 2023

8

Ethan Dmitrovsky

Ethan

Dmitrovsky

1 reference

19 October 2023

7

Sarah J Freemantle

Sarah J

Freemantle

1 reference

19 October 2023

Sutisak Kitareewan

1

Sutisak

Kitareewan

1 reference

19 October 2023

David Sekula

3

David

Sekula

1 reference

19 October 2023

Christopher H Lowrey

4

Christopher H

Lowrey

1 reference

19 October 2023

Michael J Nemeth

5

Michael J

Nemeth

1 reference

19 October 2023

Todd R Golub

6

Todd R

Golub

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

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publication date

19 March 2002

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published in

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volume

99

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issue

6

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page(s)

3806-11

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cites work

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A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme

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Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway

24 March 2017

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

24 March 2017

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PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia

24 March 2017

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Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells

24 March 2017

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

24 March 2017

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Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation

24 March 2017

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

7 April 2017

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The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines

7 April 2017

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Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

27 September 2017

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Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation

27 September 2017

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CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment

27 September 2017

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Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells

27 September 2017

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Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein

27 September 2017

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Targeting of PML/RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells

27 September 2017

1 reference

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Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization

27 September 2017

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Posttranslational regulation of cyclin D1 by retinoic acid: a chemoprevention mechanism

27 September 2017

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Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients

27 September 2017

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A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

27 September 2017

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The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122605

Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.

27 September 2017

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Proteasomes play an essential role in thymocyte apoptosis

27 September 2017

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A gene from human chromosome region 3p21 with reduced expression in small cell lung cancer

27 September 2017

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NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3).

27 September 2017

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A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated.

30 May 2018

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.052011299

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.052011299

Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/11891284

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.052011299

1 reference

release_jyxxb5yduja5bomtbigeuzn5o4

0 references

0 references

3966595

1 reference

1 reference

3966595

1 reference