CDK targets Sae2 to control DNA-end resection and homologous recombination (Q24328867)

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12 January 2020

title

CDK targets Sae2 to control DNA-end resection and homologous recombination (English)

1 reference

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RB binding protein 8, endonuclease

12 January 2020

main subject

1 reference

DNA double-strand break processing involved in repair via single-strand annealing

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Pablo Huertas

1

1 reference

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12 January 2020

Felipe Cortes Ledesma

2

1 reference

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12 January 2020

Alessandro A Sartori

3

1 reference

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12 January 2020

Andrés Aguilera

4

1 reference

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12 January 2020

Stephen P Jackson

5

1 reference

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12 January 2020

author name string

Felipe Cortés-Ledesma

2

0 references

language of work or name

English

0 references

publication date

20 August 2008

1 reference

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12 January 2020

1 reference

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12 January 2020

volume

455

1 reference

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12 January 2020

issue

7213

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12 January 2020

page(s)

689-692

1 reference

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Human CtIP promotes DNA end resection

12 January 2020

cites work

1 reference

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CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

19 March 2017

1 reference

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Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Cyclin-binding motifs are essential for the function of p21CIP1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange.

19 March 2017

1 reference

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DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

A General Method for Identifying Recessive Diploid-Specific Mutations in Saccharomyces cerevisiae, Its Application to the Isolation of Mutants Blocked at Intermediate Stages of Meiotic Prophase and Characterization of a New Gene SAE2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

The tandem affinity purification (TAP) method: a general procedure of protein complex purification

19 March 2017

1 reference

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Regulation of DNA double-strand break repair pathway choice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Topoisomerase I inhibitors: camptothecins and beyond

19 March 2017

1 reference

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Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

A chemical switch for inhibitor-sensitive alleles of any protein kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination

27 September 2017

1 reference

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Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining

27 September 2017

1 reference

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Endonucleolytic processing of covalent protein-linked DNA double-strand breaks

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle

27 September 2017

1 reference

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DSB repair: the yeast paradigm

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.

27 September 2017

1 reference

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Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

27 September 2017

1 reference

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Enhancement of Saccharomyces cerevisiae end-joining efficiency by cell growth stage but not by impairment of recombination

30 May 2018

1 reference

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Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae.

30 May 2018

1 reference

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Repair of DNA double strand breaks: in vivo biochemistry.

30 May 2018

1 reference

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The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635538

Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells.

29 November 2018

1 reference

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The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18716619

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE07215

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18716619%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 January 2020

1031468320

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18716619%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

18716619

2 references