PIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulum (Q24317767)

protein modification process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

R Watanabe

1

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T Kinoshita

2

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R Masaki

3

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A Yamamoto

4

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J Takeda

5

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N Inoue

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

25 October 1996

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published in

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volume

271

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issue

43

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page(s)

26868-75

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cites work

Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures

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The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors

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The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

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Somatic genetic analysis of the expression of cell surface molecules

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Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins

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Identification of six complementation classes involved in the biosynthesis of glycosylphosphatidylinositol anchors in Saccharomyces cerevisiae.

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Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer.

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The GPI anchor of cell-surface proteins is synthesized on the cytoplasmic face of the endoplasmic reticulum.

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The Cloning of PIG-A, a Component in the Early Step of GPI-Anchor Biosynthesis

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Molecular cloning of murine pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus

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Identification of SPT14/CWH6 as the yeast homologue of hPIG-A, a gene involved in the biosynthesis of GPI anchors

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An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

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Microsomal aldehyde dehydrogenase is localized to the endoplasmic reticulum via its carboxyl-terminal 35 amino acids

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

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Isolation of subcellular organelles

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A class of membrane proteins with a C-terminal anchor

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Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria

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Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene.

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A new method for simultaneous purification of cytochrome b5 and NADPH-cytochrome c reductase from rat liver microsomes

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Defective glycosyl phosphatidylinositol anchor synthesis and paroxysmal nocturnal hemoglobinuria.

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