BRD7 is a candidate tumour suppressor gene required for p53 function (Q24303120)

GOA release 2020-03-11

Bromodomain containing 7

1 reference

positive regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Jarno Drost

1

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Giannino Del Sal

object named as

Giannino Del Sal

11

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Reuven Agami

object named as

Reuven Agami

10

0 references

Henne Holstege

object named as

Henne Holstege

6

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author name string

Fiamma Mantovani

2

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Francesca Tocco

3

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Ran Elkon

4

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Anna Comel

5

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Ron Kerkhoven

7

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Jos Jonkers

8

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P Mathijs Voorhoeve

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

9

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language of work or name

English

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publication date

April 2010

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published in

Nature Cell Biology

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volume

12

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issue

4

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page(s)

380-9

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cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

p21 transcription is regulated by differential localization of histone H2A.Z.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Dose-dependent inhibition of thyroid differentiation by RAS oncogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Microarray-based determination of estrogen receptor, progesterone receptor, and HER2 receptor status in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

BRD7, a novel bromodomain gene, inhibits G1-S progression by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Absence of p53 gene mutations in primary nasopharyngeal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

c-Myc accelerates S-phase and requires WRN to avoid replication stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Analysis and Molecular Cloning of Differentially Expressing Genes in Nasopharyngeal Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Tumour biology: senescence in premalignant tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Live or let die: the cell's response to p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

An integrated software system for analyzing ChIP-chip and ChIP-seq data

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Creation of human tumour cells with defined genetic elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Chromatin modifications and their function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Role for BRG1 in cell cycle control and tumor suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Genomewide scan for loss of heterozygosity and chromosomal amplification in breast carcinoma using single-nucleotide polymorphism arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

DNA-dependent acetylation of p53 by the transcription coactivator p300.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

BRD7 suppresses the growth of Nasopharyngeal Carcinoma cells (HNE1) through negatively regulating beta-catenin and ERK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

EXPANDER--an integrative program suite for microarray data analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

A gene-expression signature as a predictor of survival in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

The tumor-suppressive functions of the human INK4A locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/20228809

12 December 2020