The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression (Q24299196)

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10 January 2020

title

The GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppression (English)

1 reference

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10 January 2020

0 references

1 reference

3

1 reference

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10 January 2020

Yurii Chinenov

4

1 reference

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10 January 2020

author name string

Michael M Reily

1

1 reference

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10 January 2020

Carlos Pantoja

2

1 reference

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10 January 2020

Inez Rogatsky

5

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10 January 2020

language of work or name

English

0 references

publication date

15 December 2005

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10 January 2020

1 reference

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10 January 2020

volume

25

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10 January 2020

issue

1

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10 January 2020

page(s)

108-117

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The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

10 January 2020

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

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Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1

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Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

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Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

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The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

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TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors

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GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors

19 March 2017

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Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes

19 March 2017

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Functional role of type I and type II interferons in antiviral defense

19 March 2017

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Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

19 March 2017

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Structure and specificity of nuclear receptor-coactivator interactions

19 March 2017

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IRF-7 is the master regulator of type-I interferon-dependent immune responses

19 March 2017

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Triggering the interferon antiviral response through an IKK-related pathway

19 March 2017

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

19 March 2017

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NF-kappaB regulation in the immune system

19 March 2017

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Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains

19 March 2017

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AP-1 as a regulator of cell life and death

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.

27 September 2017

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27 September 2017

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Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates

27 September 2017

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27 September 2017

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ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance

27 September 2017

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27 September 2017

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TGF-beta-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation

27 September 2017

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Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter

27 September 2017

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mRNA is an endogenous ligand for Toll-like receptor 3.

27 September 2017

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Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

27 September 2017

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The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression

27 September 2017

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A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects

27 September 2017

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Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

27 September 2017

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IRF3 mediates a TLR3/TLR4-specific antiviral gene program

27 September 2017

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IL-2 and autoimmune disease

27 September 2017

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Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex

27 September 2017

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Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones

27 September 2017

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27 September 2017

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27 September 2017

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Glucocorticoids in T cell development and function*.

27 September 2017

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The role of chemokines in Hodgkin's disease

27 September 2017

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The steroid receptor coactivator, GRIP-1, is necessary for MEF-2C-dependent gene expression and skeletal muscle differentiation.

27 September 2017

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Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.

27 September 2017

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Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor

27 September 2017

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Viruses, cytokines, antigens, and autoimmunity

27 September 2017

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Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

27 September 2017

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Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions

30 May 2018

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Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

30 May 2018

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Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumour

30 May 2018

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Immune Interferon in the Circulation of Patients with Autoimmune Disease

30 May 2018

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Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.

30 May 2018

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IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

29 November 2018

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Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity

29 November 2018

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Predicting intrinsic disorder from amino acid sequence

29 November 2018

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Circulating human plasmacytoid dendritic cells are highly sensitive to corticosteroid administration

29 November 2018

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Expression and function of chemokine receptors in human multiple myeloma.

29 November 2018

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Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

29 November 2018

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Allosteric effects of DNA on transcriptional regulators

29 November 2018

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Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16362036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16362036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16362036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7600919

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362036%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16362036%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

16362036

2 references