The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation (Q24298669)

Crumbs cell polarity complex component 3

1 reference

Membrane palmitoylated protein 5

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Discs large MAGUK scaffold protein 1

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protein localization to plasma membrane

1 reference

author

Kris Gevaert

4

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author name string

Volker M Stucke

1

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Evy Timmerman

2

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Joel Vandekerckhove

3

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Alan Hall

Molecular Biology of the Cell

5

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language of work or name

English

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publication date

May 2007

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published in

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volume

18

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issue

5

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page(s)

1744-55

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cites work

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The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

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A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia

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Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures

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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

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An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

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A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells

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Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions

19 March 2017

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The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

19 March 2017

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Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

19 March 2017

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Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse

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The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions

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hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells

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A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation

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E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeleton

19 March 2017

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Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

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Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts

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Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells

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PATJ regulates tight junction formation and polarity in mammalian epithelial cells

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Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble

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Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

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Parsing the polarity code

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Loss of PALS1 expression leads to tight junction and polarity defects.

27 September 2017

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Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells

27 September 2017

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Molecular mechanisms of epithelial morphogenesis

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Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

27 September 2017

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Epithelial cell polarity and cell junctions in Drosophila

27 September 2017

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PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

27 September 2017

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Synaptic targeting and localization of discs-large is a stepwise process controlled by different domains of the protein

27 September 2017

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Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts

27 September 2017

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hCASK and hDlg associate in epithelia, and their src homology 3 and guanylate kinase domains participate in both intramolecular and intermolecular interactions

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A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

27 September 2017

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Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans

27 September 2017

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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

27 September 2017

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29 November 2018

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Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

29 November 2018

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