Role of SIRT1 in homologous recombination (Q24297067)

single strand break repair

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Miriam Uhl

1

0 references

Andreea Csernok

2

0 references

Sevtap Aydin

3

0 references

Rolf Kreienberg

4

0 references

Lisa Wiesmüller

5

0 references

Susanne Andrea Gatz

A new role of the rDNA and nucleolus in the nucleus--rDNA instability maintains genome integrity

6

0 references

language of work or name

English

0 references

publication date

4 April 2010

0 references

published in

DNA Repair

0 references

volume

9

0 references

issue

4

0 references

page(s)

383-93

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

A sensitive test for the detection of specific DSB repair defects in primary cells from breast cancer specimens

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Chromatin structure influences the sensitivity of DNA to gamma-radiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

The emerging role of poly(ADP-ribose) polymerase-1 in longevity

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

DNA repair, genome stability, and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Human MutL-complexes monitor homologous recombination independently of mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

The transcriptional response to distinct growth factors is impaired in Werner syndrome cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

The role of WRN in DNA repair is affected by post-translational modifications.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

SIRT1 regulates the function of the Nijmegen breakage syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Crosstalk between histone modifications during the DNA damage response.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Mending the Break: Two DNA Double-Strand Break Repair Machines in Eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Intrinsic ssDNA annealing activity in the C-terminal region of WRN.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Regulation of DNA double-strand break repair pathway choice

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

SIRT1 promotes DNA repair activity and deacetylation of Ku70

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Sirtuins: critical regulators at the crossroads between cancer and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Sirtuins in mammals: insights into their biological function

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

DNA damage-induced translocation of the Werner helicase is regulated by acetylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

WRN interacts physically and functionally with the recombination mediator protein RAD52

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Werner syndrome protein limits MYC-induced cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Human ribosomal RNA gene arrays display a broad range of palindromic structures.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Werner syndrome protein--unwinding function to explain disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

DNA substrate dependence of p53-mediated regulation of double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Homologous recombination resolution defect in werner syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Pathways of DNA double-strand break repair during the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Genetic steps of mammalian homologous repair with distinct mutagenic consequences

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021

The critical role of the class III histone deacetylase SIRT1 in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2009.12.020

7 January 2021