Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex (Q24296462)

Negative elongation factor complex member B

1 reference

Negative elongation factor complex member A

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Negative elongation factor complex member E

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author name string

Takashi Narita

1

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Yuki Yamaguchi

2

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Keiichi Yano

3

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Seiji Sugimoto

4

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Sittinan Chanarat

5

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Tadashi Wada

6

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Dong-ki Kim

7

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Jun Hasegawa

8

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Masashi Omori

9

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Naoto Inukai

10

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Masaki Endoh

11

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Tomoko Yamada

12

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Hiroshi Handa

Molecular and Cellular Biology

13

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language of work or name

English

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publication date

March 2003

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published in

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volume

23

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issue

6

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page(s)

1863-73

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cites work

Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.

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Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences

19 March 2017

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BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

19 March 2017

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Domains in the SPT5 protein that modulate its transcriptional regulatory properties

19 March 2017

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Tat-SF1 protein associates with RAP30 and human SPT5 proteins

19 March 2017

1 reference

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Comparative analysis of a novel gene from the Wolf-Hirschhorn/Pitt-Rogers-Danks syndrome critical region

19 March 2017

1 reference

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A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription

19 March 2017

1 reference

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Structure and function of the human transcription elongation factor DSIF

19 March 2017

1 reference

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Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

19 March 2017

1 reference

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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

19 March 2017

1 reference

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RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

19 March 2017

1 reference

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The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

19 March 2017

1 reference

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Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

19 March 2017

1 reference

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Phosphorylation of the RNA polymerase II carboxy-terminal domain by the Bur1 cyclin-dependent kinase

19 March 2017

1 reference

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Activation of the cyclin-dependent kinase CTDK-I requires the heterodimerization of two unstable subunits

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

19 March 2017

1 reference

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7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

19 March 2017

1 reference

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

A highly purified RNA polymerase II elongation control system

19 March 2017

1 reference

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Stimulation of RNA polymerase II elongation by hepatitis delta antigen

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Characterization of TH1 and CTSZ, two non-imprinted genes downstream of GNAS1 in chromosome 20q13

19 March 2017

1 reference

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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

19 March 2017

1 reference

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P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

19 March 2017

1 reference

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Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

7 April 2017

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Novel domains and orthologues of eukaryotic transcription elongation factors.

7 April 2017

1 reference

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The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo

27 September 2017

1 reference

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Transcription elongation: the 'Foggy' is liftingellipsis.

27 September 2017

1 reference

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SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes

27 September 2017

1 reference

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High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Flavopiridol inhibits P-TEFb and blocks HIV-1 replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

P-TEFb kinase recruitment and function at heat shock loci

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

HIV-1 Tat: coping with negative elongation factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

The molecular biology of hepatitis delta virus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Basic mechanisms of transcript elongation and its regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

KOW: a novel motif linking a bacterial transcription factor with ribosomal proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

Requirement for E. coli NusG protein in factor-dependent transcription termination

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

NusG, a new Escherichia coli elongation factor involved in transcriptional antitermination by the N protein of phage lambda

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149481

A regulator of transcriptional elongation controls vertebrate neuronal development

30 May 2018

1 reference