Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β (Q24292861)

2

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Naoki Shimada

3

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Go Kagiya

4

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Etsuro Ohta

5

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Kei Tamura

6

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Hiroko Maruyama

7

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Takafumi Ichikawa

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

8

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language of work or name

English

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publication date

December 2011

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published in

FEBS Journal

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volume

278

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issue

24

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page(s)

4895-904

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cites work

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Mechanisms of tau-induced neurodegeneration

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

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Neurodegenerative tauopathies

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

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Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

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Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments

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Cellular co-localization of phosphorylated tau- and NACP/alpha-synuclein-epitopes in lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies

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Colocalization of Tau and Alpha-Synuclein Epitopes in Lewy Bodies

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Alpha-synuclein in Lewy bodies

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alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

21 January 2018

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Alpha-Synuclein contributes to GSK-3beta-catalyzed Tau phosphorylation in Parkinson's disease models

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Biochemical characterization of phospholipids, sulfatide and heparin as potent stimulators for autophosphorylation of GSK-3beta and the GSK-3beta-mediated phosphorylation of myelin basic protein in vitro

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 January 2018

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Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex

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Tissue transglutaminase modulates alpha-synuclein oligomerization

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Tau protein binds to microtubules through a flexible array of distributed weak sites

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Brain levels of microtubule-associated protein tau are elevated in Alzheimer's disease: a radioimmuno-slot-blot assay for nanograms of the protein

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Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments

21 January 2018

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Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

21 January 2018

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Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

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A novel consensus phosphorylation motif in sulfatide- and cholesterol-3-sulfate-binding protein substrates for CK1 in vitro

21 January 2018

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