T cell regulation of p62(dok) (Dok1) association with Crk-L (Q24291680)

regulation of Ras protein signal transduction

GOA release 2020-03-11

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Journal of Biological Chemistry

GOA release 2020-03-11

4

B E Bierer

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author name string

M P Martelli

series ordinal

1

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J Boomer

series ordinal

2

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M Bu

series ordinal

3

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language of work or name

English

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publication date

7 December 2001

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published in

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volume

276

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issue

49

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page(s)

45654-61

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cites work

Signal transduction by the TCR for antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The Syk family of protein tyrosine kinases in T-cell activation and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Antigen receptor signaling: integration of protein tyrosine kinase functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

T cell antigen-receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Signaling takes shape in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The T cell receptor/CD3 complex and CD2 stimulate the tyrosine phosphorylation of indistinguishable patterns of polypeptides in the human T leukemic cell line Jurkat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Physical association of the cytoplasmic domain of CD2 with the tyrosine kinases p56lck and p59fyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Signal transduction by the CD2 antigen in T cells and natural killer cells: requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptor, Fc gamma RIIIA (CD16)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Identification of a signaling complex involving CD2, zeta chain and p59fyn in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

CD2-mediated signaling in T cells lacking the zeta-chain-specific immune receptor tyrosine-based activation (ITAM) motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The transmembrane region of CD2-associated signal-transducing proteins is crucial for the outcome of CD2-mediated T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

CD2-mediated adhesion facilitates T lymphocyte antigen recognition function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Tyrosine phosphorylation and association with phospholipase C gamma-1 of the GAP-associated 62-kD protein after CD2 stimulation of Jurkat T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

p62dok negatively regulates CD2 signaling in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Chronic myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Molecular biology of chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Mechanisms of transformation by the BCR/ABL oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Differential effects of B cell receptor and B cell receptor-FcgammaRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Mediation by the protein-tyrosine kinase Tec of signaling between the B cell antigen receptor and Dok-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

SHP-1 regulation of p62(DOK) tyrosine phosphorylation in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Rap1 signalling: adhering to new models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Role of Crk oncogene product in physiologic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Activation of the Rap1 GTPase by the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Physiological signals and oncogenesis mediated through Crk family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

CMS: an adapter molecule involved in cytoskeletal rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Coordinate regulation of T cell activation by CD2 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

A critical role for p59fyn in CD2-based signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Priming of CD2-induced p62Dok tyrosine phosphorylation by CD3 in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Differential requirement of ZAP-70 for CD2-mediated activation pathways of mature human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

ZAP-70 is required for calcium mobilization but is dispensable for mitogen-activated protein kinase (MAPK) superfamily activation induced via CD2 in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200