Role of Infection in the Pathogenesis of Alzheimerʼs Disease (Q22305814)

Dimensions Publication ID

Dimensions

1029626469

7 February 2023

Darren Cotterell

series ordinal

2

author given names

Darren

author last names

Cotterell

1 reference

Dimensions Publication ID

Dimensions

1029626469

Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses

7 February 2023

language of work or name

English

0 references

publication date

December 2009

0 references

published in

CNS Drugs

0 references

volume

23

0 references

issue

12

0 references

page(s)

993-1002

0 references

cites work

1 reference

https://api.crossref.org/works/10.2165%2F11310910-000000000-00000

The viral hypothesis of Alzheimer's disease. Absence of antibodies to lentiviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11310910-000000000-00000

A new respiratory tract pathogen: Chlamydia pneumoniae strain TWAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11310910-000000000-00000

Failure to detect Chlamydia pneumoniae in brain tissues of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11310910-000000000-00000

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Herpes simplex encephalitis: involvement of apolipoprotein E genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Concurrent neuroborreliosis and Alzheimer's disease: analysis of the evidence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Alzheimer's disease--a spirochetosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Challenges and directions for the pathogen hypothesis of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Selective loss of central cholinergic neurons in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Chronic inflammation and amyloidogenesis in Alzheimer's disease -- role of Spirochetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Biological basis of the behavior of sick animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Inhibition of apoptosis in neuronal cells infected with Chlamydophila (Chlamydia) pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Association between dementia and infectious disease: evidence from a case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Failure to detect Chlamydia pneumoniae in the late-onset Alzheimer's brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Perispinal Etanercept for Treatment of Alzheimers Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

The load of Chlamydia pneumoniae in the Alzheimer's brain varies with APOE genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

The role of inflammation in CNS injury and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Lack of evidence of Borrelia involvement in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Lack of evidence for Borrelia burgdorferi seropositivity in Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Plaques of Alzheimer's disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Infection and Alzheimer's disease: the APOE epsilon4 connection and lipid metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Age and neuroinflammation: a lifetime of psychoneuroimmune consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Arguments against the involvement of Borrelia burgdorferi sensu lato in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Glial cell dysregulation: a new perspective on Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

The inflammatory reflex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Coexistence of Alzheimer disease neuropathology with herpes simplex encephalitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Alzheimer's disease and Helicobacter pylori infection: Defective immune regulation and apoptosis as proposed common links

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

"Limbic predilection in Alzheimer dementia: is reactivated herpesvirus involved?".

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Alzheimer's disease and peripheral infections: the possible contribution from periodontal infections, model and hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

A study of viral genomes and antigens in brains of patients with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Peripheral infection and aging interact to impair hippocampal memory consolidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Neurological disease and herpes simplex virus. An immunohistochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Toll-like receptor 4 on nonhematopoietic cells sustains CNS inflammation during endotoxemia, independent of systemic cytokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

An infectious conspiracy: the case for HSV-1 and APOEepsilon4 in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Inflammatory proteins in plasma and the risk of dementia: the rotterdam study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Inflammation and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/19958038

1 reference

12 December 2020

Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Chlamydophila pneumoniae and the etiology of late-onset Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Delirium in older medical inpatients and subsequent cognitive and functional status: a prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Herpes simplex virus type 1, apolipoprotein E and Alzheimer' disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Lack of association between HSV-1 DNA in the brain, Alzheimer's disease and apolipoprotein E4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Solution conformation and amyloid-like fibril formation of a polar peptide derived from a beta-hairpin in the OspA single-layer beta-sheet.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Past exposure to vaccines and subsequent risk of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

A sero-epidemiological study of conventional infectious agents in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Evaluation of CSF-Chlamydia pneumoniae, CSF-tau, and CSF-Abeta42 in Alzheimer's disease and vascular dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Systemic infections and inflammation affect chronic neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

A randomized, controlled trial of doxycycline and rifampin for patients with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Concurrent neocortical borreliosis and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Herpes simplex virus interferes with amyloid precursor protein processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Perispinal etanercept: potential as an Alzheimer therapeutic

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Association of HSV1 and apolipoprotein E-varepsilon4 in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Chlamydia pneumoniae induces Alzheimer-like amyloid plaques in brains of BALB/c mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Herpes simplex virus type 1 in Alzheimer's disease: the enemy within

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Chlamydophila (Chlamydia) pneumoniae in the Alzheimer's brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Inflammatory response: pathway across the blood-brain barrier.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19958038

12 December 2020

Chlamydophila Pneumoniae and the Etiology of Late-Onset Alzheimer's Disease

1 reference