A phosphotyrosine displacement mechanism for activation of Src by PTPalpha (Q22253266)

8 February 2023

R J Resnick

series ordinal

2

author given names

R J

author last names

Resnick

1 reference

8 February 2023

D Shalloway

series ordinal

3

author given names

D

author last names

Shalloway

1 reference

Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn

8 February 2023

language of work or name

English

0 references

publication date

1 March 2000

0 references

published in

The EMBO Journal

0 references

volume

19

0 references

issue

5

0 references

page(s)

964-78

0 references

cites work

1 reference

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Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains

19 March 2017

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Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells

19 March 2017

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Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein

19 March 2017

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Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation

19 March 2017

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Functional interaction between c-Src and its mitotic target, Sam 68

19 March 2017

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Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo

19 March 2017

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Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase

19 March 2017

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19 March 2017

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Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

19 March 2017

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19 March 2017

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Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain

19 March 2017

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19 March 2017

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19 March 2017

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

19 March 2017

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Crystal structure of the Src family tyrosine kinase Hck

19 March 2017

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Three-dimensional structure of the tyrosine kinase c-Src

19 March 2017

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Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

19 March 2017

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SH2 domains recognize specific phosphopeptide sequences

19 March 2017

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Protein modules and signalling networks

19 March 2017

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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

19 March 2017

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Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha

19 March 2017

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Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion

19 March 2017

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Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase

19 March 2017

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Kinetic analysis of two closely related receptor-like protein-tyrosine-phosphatases, PTP alpha and PTP epsilon

19 March 2017

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The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane

19 March 2017

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Identification of an additional member of the protein-tyrosine-phosphatase family: evidence for alternative splicing in the tyrosine phosphatase domain

19 March 2017

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Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

19 March 2017

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Receptor tyrosine phosphatase R-PTP-alpha is tyrosine-phosphorylated and associated with the adaptor protein Grb2

19 March 2017

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Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

19 March 2017

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The structure of an antigenic determinant in a protein

19 March 2017

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Cellular functions regulated by Src family kinases

7 April 2017

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

7 April 2017

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

7 April 2017

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Src family kinases are required for integrin but not PDGFR signal transduction.

7 April 2017

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Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

10 May 2017

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Regulation, substrates and functions of src

10 May 2017

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Src: more than the sum of its parts

10 May 2017

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Protein tyrosine phosphatases in signal transduction.

27 September 2017

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Association between receptor protein-tyrosine phosphatase RPTPalpha and the Grb2 adaptor. Dual Src homology (SH) 2/SH3 domain requirement and functional consequences

27 September 2017

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Recognition and specificity in protein tyrosine kinase-mediated signalling

27 September 2017

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Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases

27 September 2017

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A transmembrane protein-tyrosine phosphatase contains spectrin-like repeats in its extracellular domain.

27 September 2017

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Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets

27 September 2017

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Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis

27 September 2017

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A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice

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c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

27 September 2017

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Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides

27 September 2017

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Overexpression of the c-src protein does not induce transformation of NIH 3T3 cells

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Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

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Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells

27 September 2017

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Regulation by the autophosphorylation site in overexpressed pp60c-src

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Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src

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The receptor-like protein tyrosine phosphatase HPTP alpha has two active catalytic domains with distinct substrate specificities

27 September 2017

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Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells

27 September 2017

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Role of p34cdc2-mediated phosphorylations in two-step activation of pp60c-src during mitosis

27 September 2017

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27 September 2017

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27 September 2017

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Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases

30 May 2018

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Tyrosine dephosphorylation of pp60c-src is stimulated by a serine/threonine phosphatase inhibitor.

30 May 2018

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Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

30 May 2018

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Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

30 May 2018

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Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

30 May 2018

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Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells

30 May 2018

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Association of p60c-src with polyoma virus middle-T antigen abrogating mitosis-specific activation

30 May 2018

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Altered tyrosine 527 phosphorylation and mitotic activation of p60c-src

30 May 2018

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Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase.

30 May 2018

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Protein tyrosine phosphatase-1C is rapidly phosphorylated in tyrosine in macrophages in response to colony stimulating factor-1.

30 May 2018

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Expression of c-src and c-abl in embryonal carcinoma cells and adult mouse tissues

30 May 2018

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Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study

21 January 2018

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Targeted disruption of the tyrosine phosphatase PTPalpha leads to constitutive downregulation of the kinases Src and Fyn.

21 January 2018

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Accessibility of the c-Src SH2-domain for binding is increased during mitosis.

21 January 2018

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Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

29 November 2018

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Translocation of an SH2-containing protein tyrosine phosphatase (SH-PTP1) to the cytoskeleton of thrombin-activated platelets

21 January 2018

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12 December 2020

Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts

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12 December 2020

Comparative study of three protein-tyrosine phosphatases. Chicken protein-tyrosine phosphatase lambda dephosphorylates c-Src tyrosine 527

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12 December 2020

Cdc2-mediated modulation of pp60c-src activity

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12 December 2020

Induction of altered c-src product during neural differentiation of embryonal carcinoma cells

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12 December 2020

Comparative kinetic analysis and substrate specificity of the tandem catalytic domains of the receptor-like protein-tyrosine phosphatase alpha

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12 December 2020

pp60c-src is developmentally regulated in the neural retina

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12 December 2020

Association of the protein tyrosine phosphatase PTP1C with the protein tyrosine kinase c-Src in human platelets

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/19.5.964

1 reference

1 reference

1 reference

1 reference