Rethinking schizophrenia (Q22251086)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21068826

24 August 2024

1

Thomas R. Insel

Thomas R.

Insel

1 reference

Dimensions Publication ID

Dimensions

1047852061

full work available at URL

6 February 2023

language of work or name

English

0 references

publication date

11 November 2010

0 references

https://www.nature.com/articles/nature09552.pdf

file format

Portable Document Format

online access status

open access

1 reference

Europe PubMed Central

PubMed publication ID

21068826

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21068826

http://www.nature.com/articles/nature09552.pdf

24 August 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/NATURE09552

http://www.nature.com/articles/nature09552

24 August 2024

1 reference

https://api.crossref.org/works/10.1038/NATURE09552

24 August 2024

0 references

468

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issue

7321

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page(s)

187-193

0 references

cites work

Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk.

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12 December 2020

The significance of genetic factors in the etiology of schizophrenia: results from the national study of adoptees in Denmark

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12 December 2020

Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison.

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12 December 2020

Fetal Brain Development and Later Schizophrenia

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Copy number variations in schizophrenia: critical review and new perspectives on concepts of genetics and disease

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

The NIMH-MATRICS consensus statement on negative symptoms

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Animal models of neuropsychiatric disorders

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Where next with psychiatric illness?

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Congruencies in increased mortality rates, years of potential life lost, and causes of death among public mental health clients in eight states

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

A genome-wide investigation of SNPs and CNVs in schizophrenia

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12 December 2020

Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Schizophrenia as a disorder of neurodevelopment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Context-processing deficits in schizophrenia: converging evidence from three theoretically motivated cognitive tasks

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Progressive cortical change during adolescence in childhood-onset schizophrenia. A longitudinal magnetic resonance imaging study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

The EPPIC follow-up study of first-episode psychosis: longer-term clinical and functional outcome 7 years after index admission

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Premorbid IQ in schizophrenia: a meta-analytic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Suicide rate in schizophrenia in the Northern Finland 1966 Birth Cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Neuroimaging predictors of transition to psychosis--a systematic review and meta-analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

The schizophrenia phenotype in 22q11 deletion syndrome

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https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

The maturing architecture of the brain's default network

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Childhood cognitive functioning in schizophrenia patients and their unaffected siblings: a prospective cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Early developmental milestones and risk of schizophrenia: a 45-year follow-up of the Copenhagen Perinatal Cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Cognitive decline in schizophrenia from childhood to midlife: a 33-year longitudinal birth cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

The current status of the dopamine hypothesis of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Genetic heterogeneity in human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Implications of normal brain development for the pathogenesis of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Neuroplasticity of neocortical circuits in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Protracted developmental trajectories of GABAA receptor alpha1 and alpha2 subunit expression in primate prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Disruption of the neurexin 1 gene is associated with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Prevalence and risk factors for homelessness and utilization of mental health services among 10,340 patients with serious mental illness in a large public mental health system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Back to the future: predicting and reshaping the course of psychotic disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Prenatal infection and schizophrenia: a review of epidemiologic and translational studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

One hundred years of schizophrenia: a meta-analysis of the outcome literature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Why do many psychiatric disorders emerge during adolescence?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Synapse elimination and plasticity in developing human cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Recovery from psychotic illness: a 15- and 25-year international follow-up study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Impact of changing the Japanese term for "schizophrenia" for reasons of stereotypical beliefs of schizophrenia in Japanese youth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Effectiveness of antipsychotic drugs in patients with chronic schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Prefrontal and striatal volumes in monozygotic twins concordant and discordant for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Neurocognitive enhancement therapy with vocational services: work outcomes at two-year follow-up.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

A separate disease within the syndrome of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Neuropsychology of the prodrome to psychosis in the NAPLS consortium: relationship to family history and conversion to psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: a tyrosine hydroxylase immunohistochemical analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Can antidepressants be used to treat the schizophrenia prodrome? Results of a prospective, naturalistic treatment study of adolescents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Report from the working group conference on multisite trial design for cognitive remediation in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Differential postnatal development of catecholamine and serotonin inputs to identified neurons in prefrontal cortex of rhesus monkey

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Validity of the prodromal risk syndrome for first psychosis: findings from the North American Prodrome Longitudinal Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Rates and correlates of employment in people with schizophrenia in the UK, France and Germany.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Neurocognitive profile in 22q11 deletion syndrome and schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Cigarette smoking and mortality risk in people with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Attention, memory, and motor skills as childhood predictors of schizophrenia-related psychoses: the New York High-Risk Project.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Now you see it, now you don't--closing in on allostasis and developmental basis of psychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Medicine. What are the right targets for psychopharmacology?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Heritability estimates for psychotic disorders: the Maudsley twin psychosis series

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Understanding the role of DISC1 in psychiatric disease and during normal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

The course of neuropsychological performance and functional capacity in older patients with schizophrenia: influences of previous history of long-term institutional stay

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Cognitive and behavioral precursors of schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Risk factors for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Obstetric complications and schizophrenia: historical and meta-analytic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

CNTRICS final task selection: social cognitive and affective neuroscience-based measures

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Glutamate and schizophrenia: beyond the dopamine hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Cognitive therapy for the prevention of psychosis in people at ultra-high risk: randomised controlled trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Efficacy of using cognitive status in predicting psychosis: a 7-year follow-up.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21068826

12 December 2020

Common variants conferring risk of schizophrenia

1 reference

Crossref

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Neuroprotection in emerging psychotic disorders

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Delirium in hospitalized older patients.

1 reference

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Ciba Foundation Symposium

28

156

155

RM Murray

1991

1 reference

https://api.crossref.org/works/10.1038/NATURE09552