Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid (Q22010389)

GOA release 2020-03-11

lipid binding

1 reference

GOA release 2020-03-11

J Aoki

2

J

Aoki

1 reference

7 February 2023

6

K Murakami-Murofushi

K

Murakami-Murofushi

1 reference

7 February 2023

K Bandoh

1

K

Bandoh

1 reference

7 February 2023

H Hosono

3

H

Hosono

1 reference

7 February 2023

S Kobayashi

4

S

Kobayashi

1 reference

7 February 2023

T Kobayashi

5

T

Kobayashi

1 reference

7 February 2023

M Tsujimoto

7

M

Tsujimoto

1 reference

7 February 2023

H Arai

8

H

Arai

1 reference

7 February 2023

K Inoue

9

K

Inoue

1 reference

Journal of Biological Chemistry

7 February 2023

language of work or name

English

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publication date

24 September 1999

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published in

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volume

274

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issue

39

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page(s)

27776-85

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Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9

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EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

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Cloning and characterization of a putative G-protein coupled receptor potentially involved in development

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Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin

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Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

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A family of phospholipid autacoids: occurrence, metabolism and bioactions

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Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids

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Lysophosphatidic acid sensitizes mechanical stress-induced Ca2+ response via activation of phospholipase C and tyrosine kinase in cultured smooth muscle cells

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Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.

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Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate.

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Lysophosphatidic acid: G-protein signalling and cellular responses

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The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.

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Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis.

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Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1.

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Lysophosphatidic acid possesses dual action in cell proliferation

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Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes.

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Lysophosphatidic acid, a multifunctional phospholipid messenger

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Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

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Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid

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EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

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Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex

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An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

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Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization

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Naturally occurring analogs of lysophosphatidic acid elicit different cellular responses through selective activation of multiple receptor subtypes.

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Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

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Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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Lysophosphatidic acid induces a pertussis toxin-sensitive Ca(2+)-activated Cl- current in Xenopus laevis oocytes

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Lysophosphatidic acids induce proliferation of cultured vascular smooth muscle cells from rat aorta

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Xenopus oocytes express multiple receptors for LPA-like lipid mediators

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