DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes (Q22007974)

DNA ligase 3

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X-ray repair cross complementing 4

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DNA ligase 4

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double-strand break repair via nonhomologous end joining

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U Grawunder

1

U

Grawunder

1 reference

7 February 2023

D Zimmer

2

D

Zimmer

1 reference

7 February 2023

S Fugmann

3

S

Fugmann

1 reference

7 February 2023

K Schwarz

4

K

Schwarz

1 reference

7 February 2023

M R Lieber

5

M R

Lieber

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Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line

7 February 2023

language of work or name

English

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publication date

October 1998

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published in

Molecular Cell

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volume

2

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issue

4

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page(s)

477-84

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cites work

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7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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7 January 2021

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

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7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

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7 January 2021

DEAE-dextran enhances electroporation of mammalian cells

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7 January 2021

Unequal signal and coding joint formation in human V(D)J recombination

1 reference

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7 January 2021

Mechanistic constraints on diversity in human V(D)J recombination

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7 January 2021

V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability.

1 reference

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7 January 2021

Recent advances in understanding V(D)J recombination.

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7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

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7 January 2021

Antigen receptor gene rearrangement

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7 January 2021

DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains

1 reference

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7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

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7 January 2021

Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4.

1 reference

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7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

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7 January 2021

BRCA1 protein products ... Functional motifs...

1 reference

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7 January 2021

DNA-PK is essential only for coding joint formation in V(D)J recombination

1 reference

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7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

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7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

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7 January 2021

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

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7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

1 reference

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7 January 2021

Mammalian DNA ligases

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7 January 2021

Cloning, sequence determination, and expression in transfected cells of the coding sequence for the tox 176 attenuated diphtheria toxin A chain

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7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

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7 January 2021

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

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7 January 2021

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

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7 January 2021

Cell-free V(D)J recombination

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7 January 2021

DNA ligase IV from HeLa cell nuclei

1 reference

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7 January 2021

Definition of a core region of RAG-2 that is functional in V(D)J recombination

1 reference

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7 January 2021

RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition.

1 reference

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7 January 2021

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination

1 reference

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7 January 2021

A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks

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7 January 2021

V(D)J recombination moves in vitro

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7 January 2021

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

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7 January 2021

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

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7 January 2021

Mammalian DNA ligases

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7 January 2021

Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination

1 reference

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7 January 2021

Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

1 reference

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7 January 2021

Yeast DNA ligase IV mediates non-homologous DNA end joining

1 reference

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7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference