Fibroblast growth factor 10 (Q21984242)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35565

Cytokine IL1/FGF

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35565

1 reference

25 May 2022

1 reference

25 May 2022

growth factor activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

protein binding

IPI

1 reference

9 May 2019

The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

fibroblast growth factor receptor binding

IPI

chemoattractant activity

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Wnt5a regulates Shh and Fgf10 signaling during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

cell component

extracellular space

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 22 and its potential role during skin development and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

extracellular matrix

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35565&geneProductId=UniProtKB:O35565

collagen-containing extracellular matrix

1 reference

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35565&geneProductId=UniProtKB:O35565

biological process

organ growth

1 reference

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

semicircular canal morphogenesis

1 reference

9 May 2019

Differential requirements for FGF3, FGF8 and FGF10 during inner ear development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

limb bud formation

1 reference

9 May 2019

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

embryonic pattern specification

bud elongation involved in lung branching

2 references

1 reference

9 May 2019

Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of canonical Wnt signaling pathway

1 reference

9 May 2019

Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

muscle cell fate commitment

1 reference

9 May 2019

Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

1 reference

9 May 2019

Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

limb development

1 reference

9 May 2019

Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

radial glial cell differentiation

1 reference

9 May 2019

Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

female genitalia morphogenesis

1 reference

9 May 2019

Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

prostatic bud formation

1 reference

9 May 2019

FGF-10 plays an essential role in the growth of the fetal prostate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

mesonephros development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

blood vessel remodeling

1 reference

9 May 2019

Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

angiogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

establishment of mitotic spindle orientation

1 reference

9 May 2019

Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of ERK1 and ERK2 cascade

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

The mouse seminal vesicle shape mutation is allelic with Fgfr2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

animal organ morphogenesis

Development of the mammalian urethra is controlled by Fgfr2-IIIb

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Endogenous and ectopic gland induction by FGF-10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 10 is required for proper development of the mouse whiskers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

embryonic digestive tract morphogenesis

hair follicle morphogenesis

1 reference

9 May 2019

FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

metanephros development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of Notch signaling pathway

1 reference

9 May 2019

BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

negative regulation of cell population proliferation

1 reference

9 May 2019

Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

branch elongation involved in salivary gland morphogenesis

1 reference

9 May 2019

FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

branching involved in salivary gland morphogenesis

positive regulation of white fat cell proliferation

2 references

1 reference

9 May 2019

Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

bronchiole morphogenesis

1 reference

9 May 2019

Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

limb morphogenesis

1 reference

9 May 2019

Fgf10 is essential for limb and lung formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

blood vessel morphogenesis

1 reference

9 May 2019

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

lung development

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fgf10 is essential for limb and lung formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of fibroblast proliferation

1 reference

9 May 2019

Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

negative regulation of cell differentiation

1 reference

9 May 2019

Tumor chemopreventive activity of 3-O-acylated (--)-epigallocatechins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of epithelial cell migration

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

14 February 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of mitotic cell cycle

1 reference

9 May 2019

Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

spleen development

1 reference

9 May 2019

The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

smooth muscle cell differentiation

1 reference

9 May 2019

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of transcription, DNA-templated

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Elf5 is an epithelium-specific, fibroblast growth factor-sensitive transcription factor in the embryonic lung

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of Wnt signaling pathway

1 reference

9 May 2019

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

Harderian gland development

1 reference

9 May 2019

Endogenous and ectopic gland induction by FGF-10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

respiratory system development

1 reference

9 May 2019

Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epidermis development

1 reference

9 May 2019

Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

metanephros morphogenesis

1 reference

9 May 2019

FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

pancreas development

1 reference

9 May 2019

The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

mammary gland bud formation

1 reference

9 May 2019

Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive chemotaxis

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

mesenchymal-epithelial cell signaling involved in lung development

1 reference

9 May 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

lacrimal gland development

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Endogenous and ectopic gland induction by FGF-10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epithelial cell differentiation

1 reference

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

organ induction

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fgf3 and Fgf10 are required for mouse otic placode induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of epithelial cell proliferation

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epidermis morphogenesis

1 reference

9 May 2019

A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epithelial cell proliferation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

14 February 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

regulation of activin receptor signaling pathway

1 reference

9 May 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

chemotaxis

1 reference

9 May 2019

Wnt5a regulates Shh and Fgf10 signaling during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

embryonic genitalia morphogenesis

1 reference

9 May 2019

Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

response to lipopolysaccharide

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

thyroid gland development

1 reference

9 May 2019

FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

keratinocyte proliferation

1 reference

14 February 2019

Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

semicircular canal fusion

1 reference

9 May 2019

Identification of cis-element regulating expression of the mouse Fgf10 gene during inner ear development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

mammary gland specification

1 reference

9 May 2019

Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epithelial cell migration

1 reference

14 February 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

regulation of gene expression

1 reference

9 May 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

lung alveolus development

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

embryonic digestive tract development

1 reference

9 May 2019

Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

lung proximal/distal axis specification

1 reference

9 May 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

fibroblast growth factor receptor signaling pathway involved in mammary gland specification

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of vascular endothelial growth factor receptor signaling pathway

1 reference

9 May 2019

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

pituitary gland development

1 reference

9 May 2019

FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

response to estradiol

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

mesenchymal cell differentiation involved in lung development

1 reference

9 May 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

lung morphogenesis

1 reference

9 May 2019

Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

response to organic cyclic compound

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

somatic stem cell population maintenance

1 reference

9 May 2019

FGF10 maintains stem cell compartment in developing mouse incisors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

tissue regeneration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epithelial cell proliferation involved in salivary gland morphogenesis

2 references

cell-cell signaling

male genitalia morphogenesis

1 reference

9 May 2019

Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

salivary gland morphogenesis

1 reference

9 May 2019

Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

embryonic camera-type eye development

1 reference

9 May 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

induction of positive chemotaxis

1 reference

9 May 2019

Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

animal organ formation

1 reference

9 May 2019

FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

fibroblast growth factor receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

1 reference

9 May 2019

regulation of smoothened signaling pathway

2 references

9 May 2019

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

determination of left/right symmetry

1 reference

9 May 2019

The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

inner ear morphogenesis

positive regulation of cell population proliferation

3 references

9 May 2019

Requirement for fibroblast growth factor 10 or fibroblast growth factor receptor 2-IIIb signaling for cecal development in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

submandibular salivary gland formation

1 reference

9 May 2019

FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

digestive tract development

1 reference

9 May 2019

A genetic mechanism for cecal atresia: the role of the Fgf10 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

regulation of epithelial cell proliferation

1 reference

14 February 2019

FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

type II pneumocyte differentiation

1 reference

9 May 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

1 reference

9 May 2019

Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

epithelial tube branching involved in lung morphogenesis

Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fgf10 is essential for limb and lung formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Wnt5a regulates Shh and Fgf10 signaling during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

otic vesicle formation

regulation of signaling receptor activity

TAS

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of G1/S transition of mitotic cell cycle

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35565&geneProductId=UniProtKB:O35565

positive regulation of epithelial cell migration

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

FGF-10 induces SP-C and Bmp4 and regulates proximal-distal patterning in embryonic tracheal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

positive regulation of keratinocyte proliferation

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35565