Phorbol-12-myristate-13-acetate-induced protein 1 (Q21428178)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JM54

1 reference

12 September 2018

1 reference

12 September 2018

4 references

14 February 2019

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

Structural insights into the degradation of Mcl-1 induced by BH3 domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

cell component

mitochondrion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM54&geneProductId=UniProtKB:Q9JM54

4 references

10 October 2017

10 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM54&geneProductId=UniProtKB:Q9JM54

10 October 2017

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM54&geneProductId=UniProtKB:Q9JM54

10 October 2017

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM54&geneProductId=UniProtKB:Q9JM54

mitochondrion

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

IBA

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

HDA

biological process

1 reference

14 February 2019

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

negative regulation of mitochondrial membrane potential

1 reference

14 February 2019

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

T cell homeostasis

1 reference

14 February 2019

Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

1 reference

14 February 2019

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

positive regulation of neuron apoptotic process

1 reference

14 February 2019

Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

1 reference

14 February 2019

Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

14 February 2019

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

activation of cysteine-type endopeptidase activity involved in apoptotic process

negative regulation of fibroblast proliferation

1 reference

14 February 2019

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

response to UV

1 reference

14 February 2019

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

response to X-ray

1 reference

14 February 2019

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

release of cytochrome c from mitochondria

Integral role of Noxa in p53-mediated apoptotic response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

14 February 2019

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

apoptotic process

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

positive regulation of DNA damage response, signal transduction by p53 class mediator

1 reference

14 February 2019

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

intrinsic apoptotic signaling pathway by p53 class mediator

1 reference

14 February 2019

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

regulation of apoptotic process

regulation of apoptotic process

RCA

RCA

1 reference

1 January 2018

Comparative analysis of apoptosis and inflammation genes of mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM54&geneProductId=UniProtKB:Q9JM54

positive regulation of apoptotic process

RCA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

ISO

14 February 2019

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM54