Par-6 family cell polarity regulator alpha (Q21109340)

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mammalian protein found in Homo sapiens
  • PAR6C
  • partitioning defective 6 homolog alpha
  • par-6 partitioning defective 6 homolog alpha
  • PAR-6 alpha
  • TIP-40
  • tax interaction protein 40
  • Tax-interacting protein 40
  • PARD6A
  • partitioning-defective protein 6
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Language Label Description Also known as
English
Par-6 family cell polarity regulator alpha
mammalian protein found in Homo sapiens
  • PAR6C
  • partitioning defective 6 homolog alpha
  • par-6 partitioning defective 6 homolog alpha
  • PAR-6 alpha
  • TIP-40
  • tax interaction protein 40
  • Tax-interacting protein 40
  • PARD6A
  • partitioning-defective protein 6

Statements

molecular function
protein binding
determination method
IPI
16 references
retrieved
8 April 2019
stated in
The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1
GOA
curator
UniProt
UniProt protein ID
Q9NPB6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
GOA
curator
UniProt
UniProt protein ID
Q9NPB6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment
GOA
curator
UniProt
UniProt protein ID
Q9NPB6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformation
GOA
curator
UniProt
UniProt protein ID
Q9NPB6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
PKCzetaII is a target for degradation through the tumour suppressor protein pVHL
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
retrieved
8 April 2019
stated in
Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NPB6
determination method
IPI
cell component
biological process

Identifiers

 
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