Matrix metallopeptidase 9 (Q21105703)

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mammalian protein found in Homo sapiens
  • GELB
  • Gelatinase B
  • matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • type V collagenase
  • matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • matrix metalloproteinase-9
  • 92 kDa type IV collagenase
  • MMP9
  • 92 kDa gelatinase
  • macrophage gelatinase
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Language Label Description Also known as
English
Matrix metallopeptidase 9
mammalian protein found in Homo sapiens
  • GELB
  • Gelatinase B
  • matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • type V collagenase
  • matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • matrix metalloproteinase-9
  • 92 kDa type IV collagenase
  • MMP9
  • 92 kDa gelatinase
  • macrophage gelatinase

Statements

part of
molecular function
protein binding
determination method or standard
IPI
6 references
retrieved
8 April 2019
stated in
The subject of epidemiology
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IPI
retrieved
8 April 2019
stated in
Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IPI
retrieved
8 April 2019
stated in
Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IPI
retrieved
8 April 2019
stated in
Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IPI
retrieved
8 April 2019
stated in
SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IPI
retrieved
8 April 2019
stated in
In vitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IPI
metalloendopeptidase activity
determination method or standard
IEA
IDA
TAS
7 references
retrieved
17 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
TAS
retrieved
17 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
IEA
retrieved
17 October 2017
stated in
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
17 October 2017
stated in
Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
17 October 2017
stated in
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
17 October 2017
stated in
Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14780&geneProductId=UniProtKB:P14780
determination method or standard
IDA
metalloendopeptidase activity
determination method or standard
IBA
IDA
IEA
TAS
8 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IEA
retrieved
8 April 2019
stated in
Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IBA
cell component
biological process
proteolysis
determination method or standard
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IEA
retrieved
8 April 2019
stated in
Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages
GOA
curator
UniProt
UniProt protein ID
P14780
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA
retrieved
8 April 2019
stated in
Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14780
determination method or standard
IDA

Identifiers

PDB structure ID
 
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