Best Large Language Models

ESMFold shows how AI can give us new tools to understand the natural world, much like the microscope, which enabled us to see into the world at an infinitesimal scale and opened up a whole new understanding of life. AI can help us understand the immense scope of natural diversity, and see biology in a new way. Much of AI research has focused on helping computers understand the world in a way similar to how humans do. The language of proteins is one that is beyond human comprehension and has eluded even the most powerful computational tools. AI has the potential to open up this language to our understanding. Studying AI in new domains such as biology can also give insight into artificial intelligence more broadly. Our work reveals connections across domains: large language models that are behind advances in machine translation, natural language understanding, speech recognition, and image generation are also able to learn deep information about biology.