Tiol S-metiltransferaza
| Tiol S-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.9 | ||||||||
| CAS broj | 9029-81-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Tiol S-metiltransferaza (EC 2.1.1.9, S-metiltransferaza, tiolna metiltransferaza, TMT) je enzim sa sistematskim imenom S-adenozil-L-metionin:tiol S-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + tiol S-adenozil-L-homocistein + metil tioetar
Akceptori su H2S i mnoštvo alkil, aril i heterocikličnih tiola i hidroksi tiola.
- ↑ Borchardt, R.T. and Cheng, C.F. (1978). „Purification and characterization of rat liver microsomal thiol methyltransferase”. Biochim. Biophys. Acta 522: 340-353. PMID 623768.
- ↑ Bremer, J. and Greenberg, D.M. (1961). „Enzymic methylation of foreign sulfhydryl compounds”. Biochim. Biophys. Acta 46: 217-224.
- ↑ Weisiger, R.A. and Jakoby, W.B. (1979). „Thiol S-methyltransferase from rat liver”. Arch. Biochem. Biophys. 196: 631-637. PMID 485170.
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