SKF-89,145

SKF-89,145
(IUPAC) ime
	4-(6-metil-5,7-dihidro-4H-tieno[2,3-c]piridin-4-il)benzen-1,2-diol
Klinički podaci
Identifikatori
ATC kod	nije dodeljen
PubChem	10061214
Hemijski podaci
Formula	C14H15NO2S
Mol. masa	261,339 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C14H15NO2S/c1-15-7-11(10-4-5-18-14(10)8-15)9-2-3-12(16)13(17)6-9/h2-6,11,16-17H,7-8H2,1H3 ; Key: SYHALWYYSDMSLE-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

SKF-89,145 je lek koji delujue kao selektivni dopaminski agonist za D₁ podtip. N-desmetil derivat SKF-89,626 je isto tako selektivan agonist za D₁ sa sličnom potentnošću i selektivnošću.^[3]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ O'Boyle KM, Waddington JL (December 1987). „New substituted 1-phenyl-3-benzazepine analogues of SK&F 38393 and N-methyl-thienopyridine analogues of dihydroxynomifensine with selective affinity for the D-1 dopamine receptor in human post-mortem brain”. Neuropharmacology 26 (12): 1807–10. DOI:10.1016/0028-3908(87)90139-0. PMID 3501846.

Vanjske veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[pmid3501846-3] O'Boyle KM, Waddington JL (December 1987). „New substituted 1-phenyl-3-benzazepine analogues of SK&F 38393 and N-methyl-thienopyridine analogues of dihydroxynomifensine with selective affinity for the D-1 dopamine receptor in human post-mortem brain”. Neuropharmacology 26 (12): 1807–10. DOI:10.1016/0028-3908(87)90139-0. PMID 3501846.

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