Atipamezol – razlika između verzija

Atipamezol
(IUPAC) ime
	4-(2-Etil-1,3-dihidroinden-2-il)-3H-imidazol
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	104054-27-5
ATCvet kod	QV03AB90
PubChem	71310
ChemSpider	64427
UNII	03N9U5JAF6
KEGG	D03002
ChEMBL	CHEMBL353972
Hemijski podaci
Formula	C14H16N2
Mol. masa	212,290 g/mol
InChI
	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16) ; Key: HSWPZIDYAHLZDD-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	Samo za veterinarsku upotrebu

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Verzija od 8. aprila 2014. u 00:40

Atipamezol (Antisedan) je sintetički alfa₂-adrenergički antagonist. On se koristi za poništavanje sedativnih i analgetiskih efekata deksmedetomidina i medetomidina kod pasa.^[6] On je takođe ispitivan za moguću primenu kod ljudi kao anti-Parkinsonski lek.^[7]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Pfizer Animal Health ANTISEDAN Product Overview
↑ Pertovaara A, Haapalinna A, Sirviö J, Virtanen R (2005). „Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist”. CNS Drug Reviews 11 (3): 273–88. DOI:10.1111/j.1527-3458.2005.tb00047.x. PMID 16389294.

Spoljašnje veze

	Portal Medicina
	Portal Hemija

ANTISEDAN product information page (Pfizer Animal Health)

Šablon:Medicinsko upozorenje-lat

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Pfizer Animal Health ANTISEDAN Product Overview

[pmid16389294-7] Pertovaara A, Haapalinna A, Sirviö J, Virtanen R (2005). „Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist”. CNS Drug Reviews 11 (3): 273–88. DOI:10.1111/j.1527-3458.2005.tb00047.x. PMID 16389294.

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@@ Red 2: / Red 2: @@
 | Verifiedfields =
 | verifiedrevid = 458284977
-| IUPAC_name = 4-(2-Etil-1,3-dihidroinden-2-il)-3-{''H''-imidazol
+| IUPAC_name = 4-(2-Etil-1,3-dihidroinden-2-il)-3''H''-imidazol
 | image = Atipamezole.svg
 | width =
@@ Red 58: / Red 58: @@
 | chemical_formula =
 | C=14 | H=16 | N=2
-| molecular_weight = 212,290 -{g/mol
+| molecular_weight = 212,290 g/mol
 | smiles =
 }}
-'''Atipamezol''' (''Antisedan'') je sintetički alfa<sub>2</sub>-[[adrenergički antagonist]]. On se koristi za poništavanje sedativnih i analgetiskih efekata [[deksmedetomidin]]a i [[medetomidin]]a kod pasa.<ref>[http://www.pfizerah.com/product_overview.asp?drug=AS&country=US&lang=EN&species=CN -{Pfizer Animal Health ANTISEDAN Product Overview]</ref> On je takođe ispitivan za moguću primenu kod ljudi kao [[Parkinsonova bolest|anti-Parkinsonski]] lek.<ref name="pmid16389294">{{cite journal |author=Pertovaara A, Haapalinna A, Sirviö J, Virtanen R |title=Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist |journal=CNS Drug Reviews |volume=11 |issue=3 |pages=273–88 |year=2005 |pmid=16389294 |doi= 10.1111/j.1527-3458.2005.tb00047.x|url=}}</ref>
+'''Atipamezol''' (''Antisedan'') je sintetički alfa<sub>2</sub>-[[adrenergički antagonist]]. On se koristi za poništavanje sedativnih i analgetiskih efekata [[deksmedetomidin]]a i [[medetomidin]]a kod pasa.<ref>[http://www.pfizerah.com/product_overview.asp?drug=AS&country=US&lang=EN&species=CN Pfizer Animal Health ANTISEDAN Product Overview]</ref> On je takođe ispitivan za moguću primenu kod ljudi kao [[Parkinsonova bolest|anti-Parkinsonski]] lek.<ref name="pmid16389294">{{cite journal |author=Pertovaara A, Haapalinna A, Sirviö J, Virtanen R |title=Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist |journal=CNS Drug Reviews |volume=11 |issue=3 |pages=273–88 |year=2005 |pmid=16389294 |doi= 10.1111/j.1527-3458.2005.tb00047.x|url=}}</ref>
 ==Reference==
@@ Red 69: / Red 69: @@
 == Spoljašnje veze ==
 {{Portal-lat|Medicina|Hemija}}
-* [http://www.pfizerah.com/product_overview.asp?drug=AS&country=US&lang=EN&species=CN -{ANTISEDAN product information page (Pfizer Animal Health)]
+* [http://www.pfizerah.com/product_overview.asp?drug=AS&country=US&lang=EN&species=CN ANTISEDAN product information page (Pfizer Animal Health)]
 {{-}}
 {{Adrenergici-lat}}