Publications

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2011–Now

  1. Rivera KO, Russo F, Boileau RM, Tomlinson RE, Miclau T, Marcucio RS, Desai TA, Bahney CS. Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion. Sci. Rep. 2020 Dec 17. DOI: 10.1038/s41598-020-78983-y. PMID: 33335129

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  2. Huang X, Williams JZ, Chang R, Li Z, Burnett CE, Hernandez-Lopez R, Setiady I, Gai E, Patterson DM, Yu W, Roybal KT, Lim WA, Desai TA. DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation. Nat. Nantechnol. 2020 Dec 14; DOI: 10.1038/s41565-020-00813-z. PMID: 33318641

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  3. Huang X, Shi X, Hansen MA, Setiady I, Nemeth CL, Celli A, Huang B, Mauro T, Koval M, Desai TA. Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes. ACS Nano. 2020 Sept 17. 10.1021/acsnano.0c04866. PMID: 32940450

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  4. Finbloom JA, Demaree B, Abate AR, Desai TA. Networks of High Aspect Ratio Particles to Direct Colloidal Assembly Dynamics and Cellular Interactions. Adv Func Mat. 2020 Sept 15; DOI: 10.1002/adfm.20200

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  5. Ahadian S, Finbloom JA, Mofidar M, Diltemiz SE, Nasrollahi F, Davoodi E, Hosseini V, Mylonaki I, Sangabathuni S, Montazerian H, Fateh K, Nasiri R, Dokmeci MR, Stevens MM, Desai TA, Khademhosseini A. Micro and nanoscale technologies in oral drug delivery. Adv Drug Deliv Rev. 2020 Jul 22; S0169-409X(20)30096-X. PMID: 32707147

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  6. Finbloom JA, Sousa F, Stevens MM, Desai TA. Engineering the drug carrier biointerface to overcome biological barriers to drug delivery. Adv Drug Deliv Rev. 2020 Jun 11; S0169-409X(20)30053-3. PMID: 32535139

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  7. ​​Cao Y, Desai TA. TiO2-Based Nanotopographical Cues Attenuate the Restenotic Phenotype in Primary Human Vascular Endothelial and Smooth Muscle Cells. ACS Biomater Sci Eng. 2020 Feb 10; 6(2):923-932. PMID: 32529030.

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  8. Zamecnik CR, Levy ES, Lowe MM, Zirak B, Rosenblum MD, Desai TA. An Injectable Cytokine Trap for Local Treatment of Autoimmune Disease. Biomaterials. 2020 02; 230:119626. PMID: 31753473.

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  9. Le LV, Chendke GS, Gamsey S, Wisniewski N, Desai TA. Near-Infrared Optical Nanosensors for Continuous Detection of Glucose. J Diabetes Sci Technol. 2020 Mar; 14(2):204-211. PMID: 31709808.

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  10. Levy ES, Samy KE, Lamson NG, Whitehead KA, Kroetz DL, Desai TA. Reversible inhibition of efflux transporters by hydrogel microdevices. Eur J Pharm Biopharm. 2019 Dec; 145:76-84. PMID: 31639417.

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  11. Chendke GS, Faleo G, Juang C, Parent AV, Bernards DA, Herbok M, Tang Q, Desai TA. Supporting Survival of Transplanted Stem-Cell-Derived Insulin-Producing Cells in an Encapsulation Device Augmented with Controlled Release of Amino Acids. Adv Biosyst. 2019 Sep; 3(9). PMID: 31633004

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  12. Samy KE, Levy ES, Phong K, Demaree B, Abate AR, Desai TA. Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport. Sci Rep. 2019 Jul 09; 9(1):9936. PMID: 31289365. PMCID: PMC6616551

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  13. Cao Y, Samy KE, Bernards DA, Desai TA. Recent advances in intraocular sustained-release drug delivery devices. Drug Discov Today. 2019 Jun 04. PMID: 31173915

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  14. Nemeth CL, Lykins WR, Tran H, ElSayed MEH, Desai TA. Bottom-Up Fabrication of Multilayer Enteric Devices for the Oral Delivery of Peptides. Pharm Res. 2019 Apr 19; 36(6):89. PMID: 31004235

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  15. Le LV, Mkrtschjan MA, Russell B, Desai TA. Hang on tight: reprogramming the cell with microstructural cues. Biomed Microdevices. 2019 Apr 06; 21(2):43. PMID: 30955102

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  16. Samy KE, Cao Y, Kim J, Konichi da Silva NR, Phone A, Bloomer MM, Bhisitkul RB, Desai TA. Co-Delivery of Timolol and Brimonidine with a Polymer Thin-Film Intraocular Device. J Ocul Pharmacol Ther. 2019 Jan 07. PMID: 30615539.

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  17. Schlesinger EB, Bernards DA, Chen HH, Feindt J, Cao J, Dix D, Romano C, Bhisitkul RB, Desai TA. Device design methodology and formulation of a protein therapeutic for sustained release intraocular delivery. Bioeng Transl Med. 2019 Jan; 4(1):152-163. PMID: 30680326.

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  18. Desai TA, Tang Q. Islet encapsulation therapy - racing towards the finish line? Nat Rev Endocrinol. 2018 Nov; 14(11):630-632. PMID: 30275463.

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  19. Conte MS, Desai TA, Wu B, Schaller M, Werlin E. Pro-resolving lipid mediators in vascular disease. J Clin Invest. 2018 08 31; 128(9):3727-3735. PMID: 30168805.

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  20. Wu B, Werlin EC, Chen M, Mottola G, Chatterjee A, Lance KD, Bernards DA, Sansbury BE, Spite M, Desai TA, Conte MS. Perivascular delivery of resolvin D1 inhibits neointimal hyperplasia in a rabbit vein graft model. J Vasc Surg. 2018 Dec; 68(6S):188S-200S.e4. PMID: 30064835.

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  21. Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 2018 Jul 26; 174(3):505-520. PMID: 30053424.

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  22. Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Cell Stem Cell. 2018 Jun 01; 22(6):810-823. PMID: 29859172.

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  23. Urbano L, Clifton L, Ku HK, Kendall-Troughton H, Vandera KA, Matarese BFE, Abelha T, Li P, Desai T, Dreiss CA, Barker RD, Green MA, Dailey LA, Harvey RD. Influence of the Surfactant Structure on Photoluminescent p-Conjugated Polymer Nanoparticles: Interfacial Properties and Protein Binding. Langmuir. 2018 05 29; 34(21):6125-6137. PMID: 29726688.

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  24. Le LV, Mohindra P, Fang Q, Sievers RE, Mkrtschjan MA, Solis C, Safranek CW, Russell B, Lee RJ, Desai TA. Injectable hyaluronic acid based microrods provide local micromechanical and biochemical cues to attenuate cardiac fibrosis after myocardial infarction. Biomaterials. 2018 Jul; 169:11-21. PMID: 29631164.

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  25. Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL, Desai T, Calafiore R, de Vos P. Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes. Trends Biotechnol. 2018 04; 36(4):445-456. PMID: 29455936.

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  26. Lykins WR, Luecke E, Johengen D, van der Straten A, Desai TA. Long acting systemic HIV pre-exposure prophylaxis: an examination of the field. Drug Deliv Transl Res. 2017 Dec; 7(6):805-816. PMID: 28612340.

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  27. Mkrtschjan MA, Gaikwad SB, Kappenman KJ, Solís C, Dommaraju S, Le LV, Desai TA, Russell B. Lipid signaling affects primary fibroblast collective migration and anchorage in response to stiffness and microtopography. J Cell Physiol. 2018 04; 233(4):3672-3683. PMID: 29034471.

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  28. Zamecnik CR, Lowe MM, Patterson DM, Rosenblum MD, Desai TA. Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators. ACS Nano. 2017 11 28; 11(11):11433-11440. PMID: 29124929.

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  29. Kim J, Kudisch M, da Silva NRK, Asada H, Aya-Shibuya E, Bloomer MM, Mudumba S, Bhisitkul RB, Desai TA. Long-term intraocular pressure reduction with intracameral polycaprolactone glaucoma devices that deliver a novel anti-glaucoma agent. J Control Release. 2018 01 10; 269:45-51. PMID: 29127001.

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  30. Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai T. Nanoporous Immunoprotective Device for Stem-Cell-Derived ß-Cell Replacement Therapy. ACS Nano. 2017 Aug 22; 11(8):7747-7757. PMID: 28763191.

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  31. Lykins WR, Luecke E, Johengen D, van der Straten A, Desai TA. Long acting systemic HIV pre-exposure prophylaxis: an examination of the field. Drug Deliv Transl Res. 2017 Jun 13. PMID: 28612340.

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  32. Nuhn H, Blanco CE, Desai TA. Nanoengineered Stent Surface to Reduce In-Stent Restenosis in Vivo. ACS Appl Mater Interfaces. 2017 Jun 14; 9(23):19677-19686. PMID: 28574242.

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  33. Stewart T, Koval WT, Molina SA, Bock SM, Lillard JW, Ross RF, Desai TA, Koval M. Calibrated flux measurements reveal a nanostructure-stimulated transcytotic pathway. Exp Cell Res. 2017 Jun 15; 355(2):153-161. PMID: 28390677.

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  34. Weber RJ, Desai TA, Gartner ZJ. Non-autonomous cell proliferation in the mammary gland and cancer. Curr Opin Cell Biol. 2017 Apr; 45:55-61. PMID: 28314237.

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  35. Fox CB, Nemeth CL, Chevalier RW, Cantlon J, Bogdanoff DB, Hsiao JC, Desai TA. Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading. Bioeng Transl Med. 2017 Mar; 2(1):9-16. PMID: 28503662.

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  36. Lance KD, Chatterjee A, Wu B, Mottola G, Nuhn H, Lee PP, Sansbury BE, Spite M, Desai TA, Conte MS. Unidirectional and sustained delivery of the proresolving lipid mediator resolvin D1 from a biodegradable thin film device. J Biomed Mater Res A. 2017 Jan; 105(1):31-41. PMID: 27508346.

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  37. Lance KD, Bernards DA, Ciaccio NA, Good SD, Mendes TS, Kudisch M, Chan E, Ishikiriyama M, Bhisitkul RB, Desai TA. In vivo and in vitro sustained release of ranibizumab from a nanoporous thin-film device. Drug Deliv Transl Res. 2016 Dec; 6(6):771-780. PMID: 27178165.

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  38. Desai T, Shea LD. Advances in islet encapsulation technologies. Nat Rev Drug Discov. 2016 Dec 23. PMID: 28008169.

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  39. Cerchiari AE, Samy KE, Todhunter ME, Schlesinger E, Henise J, Rieken C, Gartner ZJ, Desai TA. Probing the luminal microenvironment of reconstituted epithelial microtissues. Sci Rep. 2016; 6:33148. PMID: 27619235.

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  40. Kim J, Kudisch M, Mudumba S, Asada H, Aya-Shibuya E, Bhisitkul RB, Desai TA. Biocompatibility and Pharmacokinetic Analysis of an Intracameral Polycaprolactone Drug Delivery Implant for Glaucoma. Invest Ophthalmol Vis Sci. 2016 Aug 1; 57(10):4341-6. PMID: 27556217.

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  41. Fox CB, Cao Y, Nemeth CL, Chirra HD, Chevalier RW, Xu AM, Melosh NA, Desai TA. Fabrication of Sealed Nanostraw Microdevices for Oral Drug Delivery. ACS Nano. 2016 Jun 28; 10(6):5873-81. PMID: 27268699.

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  42. Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, B Fox C, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR. Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Sci Rep. 2016; 6:24726. PMID: 27095412.

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  43. Wu B, Mottola G, Chatterjee A, Lance KD, Chen M, Siguenza IO, Desai TA, Conte MS. Perivascular delivery of resolvin D1 inhibits neointimal hyperplasia in a rat model of arterial injury. J Vasc Surg 2017 Jan; 65(1):207-217.e3. doi: 10.1016/j.jvs.2016.01.030. Epub 2016 Mar 29. PMID: 27034112.

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  44. Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S. Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport. Sci Rep. 2016 Mar 24; 6:23679. PMID: 27009429; PMCID: PMC4806308.

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  45. Schlesinger E, Johengen D, Luecke E, Rothrock G, McGowan I, van der Straten A, Desai T. A Tunable, Biodegradable, Thin-Film Polymer Device as a Long-Acting Implant Delivering Tenofovir Alafenamide Fumarate for HIV Pre-exposure Prophylaxis. Pharm Res. 2016 Jul; 33(7):1649-56. PMID: 26975357.

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  46. Tang Q, Desai TA. Approaching a cure for type 1 diabetes. Nat Med. 2016 Mar 3; 22(3):236-7. PMID: 26937617.

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  47. Lee PP, Desai TA. Nitinol-Based Nanotubular Arrays with Controlled Diameters Upregulate Human Vascular Cell ECM Production. ACS Biomater Sci Eng. 2016 Mar 14; 2(3):409-414. PMID: 27942579.

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  48. Allen J, Ryu J, Maggi A, Flores B, Greer JR, Desai T. Tunable Microfibers Suppress Fibrotic Encapsulation via Inhibition of TGFß Signaling. Tissue Eng Part A. 2016 Jan; 22(1-2):142-50. PMID: 26507808.

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  49. Lance KD, Good SD, Mendes TS, Ishikiriyama M, Chew P, Estes LS, Yamada K, Mudumba S, Bhisitkul RB, Desai TA. In Vitro and In Vivo Sustained Zero-Order Delivery of Rapamycin (Sirolimus) From a Biodegradable Intraocular Device. Invest Ophthalmol Vis Sci. 2015 Nov 1; 56(12):7331-7. PMID: 26559479; PMCID: PMC4642602 [Available on 05/01/16].

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  50. Walsh LA, Allen JL, Desai TA. Nanotopography applications in drug delivery. Expert Opin Drug Deliv. 2015 Dec; 12(12):1823-7. PMID: 26512871.

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  51. Todhunter ME, Jee NY, Hughes AJ, Coyle MC, Cerchiari A, Farlow J, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ. Programmed synthesis of three-dimensional tissues. Nat Methods. 2015 Oct; 12(10):975-81. PMID: 26322836; PMCID: PMC4589502 [Available on 04/01/16].

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  52. Fox CB, Kim J, Le LV, Nemeth CL, Chirra HD, Desai TA. Micro/nanofabricated platforms for oral drug delivery. J Control Release. 2015 Dec 10; 219:431-44. PMID: 26244713; PMCID: PMC4656086 [Available on 12/10/16].

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  53. Schlesinger E, Ciaccio N, Desai TA. Polycaprolactone thin-film drug delivery systems: Empirical and predictive models for device design. Mater Sci Eng C Mater Biol Appl. 2015 Dec 01; 57:232-9. PMID: 26354259; PMCID: PMC4568064 [Available on 12/01/16].

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  54. Nyitray CE, Chang R, Faleo G, Lance KD, Bernards DA, Tang Q, Desai TA. Polycaprolactone Thin-Film Micro- and Nanoporous Cell-Encapsulation Devices. ACS Nano. 2015 Jun 23; 9(6):5675-82. PMID: 25950860; PMCID: PMC4628825.

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  55. Walsh L, Ryu J, Bock S, Koval M, Mauro T, Ross R, Desai T. Nanotopography facilitates in vivo transdermal delivery of high molecular weight therapeutics through an integrin-dependent mechanism. Nano Lett. 2015 Apr 8; 15(4):2434-41. PMID: 25790174; PMCID: PMC4478088.

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  56. Simovic S, Song Y, Nann T, Desai TA. Intestinal absorption of fluorescently labeled nanoparticles. Nanomedicine. 2015 Jul; 11(5):1169-78. PMID: 25791810; PMCID: PMC4476919 [Available on 07/01/16].

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  57. Fox CB, Kim J, Schlesinger EB, Chirra HD, Desai TA. Fabrication of micropatterned polymeric nanowire arrays for high-resolution reagent localization and topographical cellular control. Nano Lett. 2015 Mar 11; 15(3):1540-6. PMID: 25639724.

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  58. Cerchiari AE, Garbe JC, Jee NY, Todhunter ME, Broaders KE, Peehl DM, Desai TA, LaBarge MA, Thomson M, Gartner ZJ. A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):2287-92. PMID: 25633040; PMCID: PMC4343104.

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  59. Peña JR, Pinney JR, Ayala P, Desai TA, Goldspink PH. Localized delivery of mechano-growth factor E-domain peptide via polymeric microstructures improves cardiac function following myocardial infarction. Biomaterials. 2015 Apr; 46:26-34. PMID: 25678113; PMCID: PMC4328136.

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  60. Kim J, Schlesinger EB, Desai TA. Nanostructured materials for ocular delivery: nanodesign for enhanced bioadhesion, transepithelial permeability and sustained delivery. Ther Deliv. 2015; 6(12):1365-76. PMID: 26652282; PMCID: PMC4893795 [Available on 12/01/16].

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  61. Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai TA, Gartner ZJ. Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding. Tissue Eng Part C Methods. 2015 Jun; 21(6):541-7. PMID: 25351430; PMCID: PMC4442595 [Available on 06/01/16].

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  62. Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA. Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. Mol Ther. 2015 Jan; 23(1):119-29. PMID: 25138755; PMCID: PMC4426791 [Available on 01/01/16].

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  63. Weber RJ, Liang SI, Selden NS, Desai TA, Gartner ZJ. Efficient targeting of fatty-acid modified oligonucleotides to live cell membranes through stepwise assembly. Biomacromolecules. 2014 Dec 8; 15(12):4621-6. PMID: 25325667; PMCID: PMC4261982.

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  64. Doroudian G, Pinney J, Ayala P, Los T, Desai TA, Russell B. Sustained delivery of MGF peptide from microrods attracts stem cells and reduces apoptosis of myocytes. Biomed Microdevices. 2014 Oct; 16(5):705-15. PMID: 24908137; PMCID: PMC4418932.

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  65. Lee PP, Cerchiari A, Desai TA. Nitinol-based nanotubular coatings for the modulation of human vascular cell function. Nano Lett. 2014 Sep 10; 14(9):5021-8. PMID: 25115216.

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  66. Uskokovic V, Desai TA. Nanoparticulate drug delivery platforms for advancing bone infection therapies. Expert Opin Drug Deliv. 2014 Dec; 11(12):1899-912. PMID: 25109804; PMCID: PMC4393954.

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  67. Wade JS, Desai TA. Planar microdevices enhance transport of large molecular weight molecules across retinal pigment epithelial cells. Biomed Microdevices. 2014 Aug; 16(4):629-38. PMID: 24789225; PMCID: PMC4082762.

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  68. Pinney JR, Melkus G, Cerchiari A, Hawkins J, Desai TA. Novel functionalization of discrete polymeric biomaterial microstructures for applications in imaging and three-dimensional manipulation. ACS Appl Mater Interfaces. 2014 Aug 27; 6(16):14477-85. PMID: 25068888; PMCID: PMC4149329.

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  69. Uskokovic V, Desai TA. Does translational symmetry matter on the micro scale? Fibroblastic and osteoblastic interactions with the topographically distinct poly(e-caprolactone)/hydroxyapatite thin films. ACS Appl Mater Interfaces. 2014 Aug 13; 6(15):13209-20. PMID: 25014232; PMCID: PMC4134142.

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  70. Pinney JR, Du KT, Ayala P, Fang Q, Sievers RE, Chew P, Delrosario L, Lee RJ, Desai TA. Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction. Biomaterials. 2014 Oct; 35(31):8820-8. PMID: 25047625; PMCID: PMC4144416.

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  71. Muthusubramaniam L, Zaitseva T, Paukshto M, Martin G, Desai T. Effect of collagen nanotopography on keloid fibroblast proliferation and matrix synthesis: implications for dermal wound healing. Tissue Eng Part A. 2014 Oct; 20(19-20):2728-36. PMID: 24724556; PMCID: PMC4195479.

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  72. Chirra HD, Shao L, Ciaccio N, Fox CB, Wade JM, Ma A, Desai TA. Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs. Adv Healthc Mater. 2014 Oct; 3(10):1648-54. PMID: 24711341; PMCID: PMC4256094.

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  73. Schweicher J, Desai TA. Facile Synthesis of Robust Free-Standing TiO2 Nanotubular Membranes for Biofiltration Applications. J Appl Electrochem. 2014 Mar 1; 44(3):411-418. PMID: 24634542.

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  74. Nyitray CE, Chavez MG, Desai TA. Compliant 3D microenvironment improves ß-cell cluster insulin expression through mechanosensing and ß-catenin signaling. Tissue Eng Part A. 2014 Jul; 20(13-14):1888-95. PMID: 24433489; PMCID: PMC4085995.

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  75. Uskokovic V, Desai TA. Simultaneous bactericidal and osteogenic effect of nanoparticulate calcium phosphate powders loaded with clindamycin on osteoblasts infected with Staphylococcus aureus. Mater Sci Eng C Mater Biol Appl. 2014 Apr 1; 37:210-22. PMID: 24582242; PMCID: PMC3942787.

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  76. Kurpinski K, Johnson T, Kumar S, Desai T, Li S. Mastering translational medicine: interdisciplinary education for a new generation. Sci Transl Med. 2014 Jan 8; 6(218):218fs2. PMID: 24401938.

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  77. Calvert KL, Desai T, Webster TJ. Advances in calcium phosphate coatings--anodic spark deposition: a review. Front Biosci (Landmark Ed). 2014; 19:475-89. PMID: 24389196.

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  78. Schweicher J, Nyitray C, Desai TA. Membranes to achieve immunoprotection of transplanted islets. Front Biosci (Landmark Ed). 2014; 19:49-76. PMID: 24389172; PMCID: PMC4230297.

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  79. Fox CB, Chirra HD, Desai TA. Planar bioadhesive microdevices: a new technology for oral drug delivery. Curr Pharm Biotechnol. 2014; 15(7):673-83. PMID: 25219863; PMCID: PMC4227534.

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  80. Uskokovic V, Desai TA. In vitro analysis of nanoparticulate hydroxyapatite/chitosan composites as potential drug delivery platforms for the sustained release of antibiotics in the treatment of osteomyelitis. J Pharm Sci. 2014 Feb; 103(2):567-79. PMID: 24382825; PMCID: PMC4045008.

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  81. Kam KR, Walsh LA, Bock SM, Ollerenshaw JD, Ross RF, Desai TA. The effect of nanotopography on modulating protein adsorption and the fibrotic response. Tissue Eng Part A. 2014 Jan; 20(1-2):130-8. PMID: 23914986; PMCID: PMC3875207.

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  82. Desai TA, Uskokovic V. Calcium phosphate nanoparticles: a future therapeutic platform for the treatment of osteomyelitis? Ther Deliv. 2013 Jun; 4(6):643-5. PMID: 23738660; PMCID: PMC3763212.

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  83. Uskokovic V, Hoover C, Vukomanovic M, Uskokovic DP, Desai TA. Osteogenic and antimicrobial nanoparticulate calcium phosphate and poly-(D,L-lactide-co-glycolide) powders for the treatment of osteomyelitis. Mater Sci Eng C Mater Biol Appl. 2013 Aug 1; 33(6):3362-73. PMID: 23706222; PMCID: PMC3672472.

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  84. Uskokovic V, Batarni SS, Schweicher J, King A, Desai TA. Effect of calcium phosphate particle shape and size on their antibacterial and osteogenic activity in the delivery of antibiotics in vitro. ACS Appl Mater Interfaces. 2013 Apr 10; 5(7):2422-31. PMID: 23484624; PMCID: PMC3647690.

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  85. Koulajian K, Desai T, Liu GC, Ivovic A, Patterson JN, Tang C, El-Benna J, Joseph JW, Scholey JW, Giacca A. NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents. Diabetologia. 2013 May; 56(5):1078-87. PMID: 23429921; PMCID: PMC3622749.

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  86. Bernards DA, Bhisitkul RB, Wynn P, Steedman MR, Lee OT, Wong F, Thoongsuwan S, Desai TA. Ocular biocompatibility and structural integrity of micro- and nanostructured poly(caprolactone) films. J Ocul Pharmacol Ther. 2013 Mar; 29(2):249-57. PMID: 23391326; PMCID: PMC3601720.

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  87. Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA. Radially branched deployment for more efficient cell transplantation at the scale of the human brain. Stereotact Funct Neurosurg. 2013; 91(2):92-103. PMID: 23343609; PMCID: PMC3739996.

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  88. Kam KR, Desai TA. Nano- and microfabrication for overcoming drug delivery challenges. J Mater Chem B Mater Biol Med. 2013; 1(14):1878-1884. PMID: 23730504.

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  89. Kam KR, Walsh LA, Bock SM, Koval M, Fischer KE, Ross RF, Desai TA. Nanostructure-mediated transport of biologics across epithelial tissue: enhancing permeability via nanotopography. Nano Lett. 2013 Jan 9; 13(1):164-71. PMID: 23186530; PMCID: PMC4418930.

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  90. Desai T. In the spotlight: Tissue engineering. IEEE Rev Biomed Eng. 2013; 6:27-8. PMID: 23192638.

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  91. Uskokovic V, Desai TA. Phase composition control of calcium phosphate nanoparticles for tunable drug delivery kinetics and treatment of osteomyelitis. II. Antibacterial and osteoblastic response. J Biomed Mater Res A. 2013 May; 101(5):1427-36. PMID: 23115128; PMCID: PMC3566302.

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  92. Uskokovic V, Desai TA. Phase composition control of calcium phosphate nanoparticles for tunable drug delivery kinetics and treatment of osteomyelitis. I. Preparation and drug release. J Biomed Mater Res A. 2013 May; 101(5):1416-26. PMID: 23115118; PMCID: PMC3566415.

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  93. Chavez MG, Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD. Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. Tissue Eng Part C Methods. 2013 Jan; 19(1):15-24. PMID: 22742471; PMCID: PMC3522131.

    View in: PubMed, PubMed Central

  94. Curtis MW, Budyn E, Desai TA, Samarel AM, Russell B. Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction. Biomech Model Mechanobiol. 2013 Jan; 12(1):95-109. PMID: 22407215; PMCID: PMC3407350.

    View in: PubMed, PubMed Central

  95. Bernards DA, Lance KD, Ciaccio NA, Desai TA. Nanostructured thin film polymer devices for constant-rate protein delivery. Nano Lett. 2012 Oct 10; 12(10):5355-61. PMID: 22985294; PMCID: PMC3480309.

    View in: PubMed, PubMed Central

  96. Chirra HD, Desai TA. Multi-reservoir bioadhesive microdevices for independent rate-controlled delivery of multiple drugs. Small. 2012 Dec 21; 8(24):3839-46. PMID: 22962019; PMCID: PMC3527694.

    View in: PubMed, PubMed Central

  97. Chirra HD, Desai TA. Emerging microtechnologies for the development of oral drug delivery devices. Adv Drug Deliv Rev. 2012 Nov; 64(14):1569-78. PMID: 22981755; PMCID: PMC3488155.

    View in: PubMed, PubMed Central

  98. Uskokovic V, Lee K, Lee PP, Fischer KE, Desai TA. Shape effect in the design of nanowire-coated microparticles as transepithelial drug delivery devices. ACS Nano. 2012 Sep 25; 6(9):7832-41. PMID: 22900471; PMCID: PMC3461957.

    View in: PubMed, PubMed Central

  99. Mendelsohn AD, Nyitray C, Sena M, Desai TA. Size-controlled insulin-secreting cell clusters. Acta Biomater. 2012 Dec; 8(12):4278-84. PMID: 22902301; PMCID: PMC4030672.

    View in: PubMed, PubMed Central

  100. Crawford C, Kennedy-Lydon T, Sprott C, Desai T, Sawbridge L, Munday J, Unwin RJ, Wildman SS, Peppiatt-Wildman CM. An intact kidney slice model to investigate vasa recta properties and function in situ. Nephron Physiol. 2012; 120(3):p17-31. PMID: 22833057.

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  101. Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD. Stem cell and biomaterials research in dental tissue engineering and regeneration. Dent Clin North Am. 2012 Jul; 56(3):495-520. PMID: 22835534; PMCID: PMC3494412.

    View in: PubMed, PubMed Central

  102. Tucker RM, Parcher BW, Jones EF, Desai TA. Single-injection HPLC method for rapid analysis of a combination drug delivery system. AAPS PharmSciTech. 2012 Jun; 13(2):605-10. PMID: 22535518; PMCID: PMC3364377.

    View in: PubMed, PubMed Central

  103. Tang C, Koulajian K, Schuiki I, Zhang L, Desai T, Ivovic A, Wang P, Robson-Doucette C, Wheeler MB, Minassian B, Volchuk A, Giacca A. Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress. Diabetologia. 2012 May; 55(5):1366-79. PMID: 22396011.

    View in: PubMed

  104. Armitage B, Desai T, Jiang S, Whitten D. Preface for the Bioinspired Assemblies and Interfaces Special Issue. Langmuir. 2012 Jan 31; 28(4):1943. PMID: 22288887.

    View in: PubMed

  105. Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L. Selective targeting of microglia by quantum dots. J Neuroinflammation. 2012; 9:22. PMID: 22272874; PMCID: PMC3292839.

    View in: PubMed, PubMed Central

  106. Muthusubramaniam L, Peng L, Zaitseva T, Paukshto M, Martin GR, Desai TA. Collagen fibril diameter and alignment promote the quiescent keratocyte phenotype. J Biomed Mater Res A. 2012 Mar; 100(3):613-21. PMID: 22213336; PMCID: PMC3266477.

    View in: PubMed, PubMed Central

  107. Uskokovic V, Lee PP, Walsh LA, Fischer KE, Desai TA. PEGylated silicon nanowire coated silica microparticles for drug delivery across intestinal epithelium. Biomaterials. 2012 Feb; 33(5):1663-72. PMID: 22116000; PMCID: PMC3237727.

    View in: PubMed, PubMed Central

  108. Roy S, Goldman K, Marchant R, Zydney A, Brown D, Fleischman A, Conlisk A, Desai T, Duffy S, Humes H, Fissell W. Implanted renal replacement for end-stage renal disease. Panminerva Med. 2011 Sep; 53(3):155-66. PMID: 21775942.

    View in: PubMed

  109. Patel AA, Desai TA, Kumar S. Microtopographical assembly of cardiomyocytes. Integr Biol (Camb). 2011 Oct; 3(10):1011-9. PMID: 21863181.

    View in: PubMed

  110. Ayala P, Desai TA. Integrin a3 blockade enhances microtopographical down-regulation of a-smooth muscle actin: role of microtopography in ECM regulation. Integr Biol (Camb). 2011 Jul; 3(7):733-41. PMID: 21666923.

    View in: PubMed

  111. Dibbens LM, Kneen R, Bayly MA, Heron SE, Arsov T, Damiano JA, Desai T, Gibbs J, McKenzie F, Mulley JC, Ronan A, Scheffer IE. Recurrence risk of epilepsy and mental retardation in females due to parental mosaicism of PCDH19 mutations. Neurology. 2011 Apr 26; 76(17):1514-9. PMID: 21519002.

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  112. Van Hoof D, Mendelsohn AD, Seerke R, Desai TA, German MS. Differentiation of human embryonic stem cells into pancreatic endoderm in patterned size-controlled clusters. Stem Cell Res. 2011 May; 6(3):276-85. PMID: 21513906.

    View in: PubMed

  113. Fischer KE, Nagaraj G, Hugh Daniels R, Li E, Cowles VE, Miller JL, Bunger MD, Desai TA. Hierarchical nanoengineered surfaces for enhanced cytoadhesion and drug delivery. Biomaterials. 2011 May; 32(13):3499-506. PMID: 21296409; PMCID: PMC3086716.

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  114. Muthusubramaniam L, Lowe R, Fissell WH, Li L, Marchant RE, Desai TA, Roy S. Hemocompatibility of silicon-based substrates for biomedical implant applications. Ann Biomed Eng. 2011 Apr; 39(4):1296-305. PMID: 21287275; PMCID: PMC3069312.

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  115. Fischer KE, Jayagopal A, Nagaraj G, Daniels RH, Li EM, Silvestrini MT, Desai TA. Nanoengineered surfaces enhance drug loading and adhesion. Nano Lett. 2011 Mar 9; 11(3):1076-81. PMID: 21280638; PMCID: PMC3053427.

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  116. Desai T. In the spotlight: tissue engineering--translation for tissue engineering and regenerative medicine. IEEE Rev Biomed Eng. 2011; 4:24-5. PMID: 22273789.

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  117. Saldanha KJ, Doan RP, Ainslie KM, Desai TA, Majumdar S. Micrometer-sized iron oxide particle labeling of mesenchymal stem cells for magnetic resonance imaging-based monitoring of cartilage tissue engineering. Magn Reson Imaging. 2011 Jan; 29(1):40-9. PMID: 20863643; PMCID: PMC3005992.

    View in: PubMed, PubMed Central

2001–2010

  1. Curtis MW, Sharma S, Desai TA, Russell B. Hypertrophy, gene expression, and beating of neonatal cardiac myocytes are affected by microdomain heterogeneity in 3D. Biomed Microdevices. 2010 Dec; 12(6):1073-85. PMID: 20668947; PMCID: PMC3102262.

    View in: PubMed, PubMed Central

  2. Ayala P, Lopez JI, Desai TA. Microtopographical cues in 3D attenuate fibrotic phenotype and extracellular matrix deposition: implications for tissue regeneration. Tissue Eng Part A. 2010 Aug; 16(8):2519-27. PMID: 20235832; PMCID: PMC2947433.

    View in: PubMed, PubMed Central

  3. Mendelsohn AD, Bernards DA, Lowe RD, Desai TA. Patterning of mono- and multilayered pancreatic beta-cell clusters. Langmuir. 2010 Jun 15; 26(12):9943-9. PMID: 20218546; PMCID: PMC2883011.

    View in: PubMed, PubMed Central

  4. Bernards DA, Desai TA. Nanotemplating of biodegradable polymer membranes for constant-rate drug delivery. Adv Mater. 2010 Jun 4; 22(21):2358-62. PMID: 20376851.

    View in: PubMed

  5. Steedman MR, Tao SL, Klassen H, Desai TA. Enhanced differentiation of retinal progenitor cells using microfabricated topographical cues. Biomed Microdevices. 2010 Jun; 12(3):363-9. PMID: 20077017; PMCID: PMC2859162.

    View in: PubMed, PubMed Central

  6. Patel AA, Thakar RG, Chown M, Ayala P, Desai TA, Kumar S. Biophysical mechanisms of single-cell interactions with microtopographical cues. Biomed Microdevices. 2010 Apr; 12(2):287-96. PMID: 20033299; PMCID: PMC2836253.

    View in: PubMed, PubMed Central

  7. Collins JM, Ayala P, Desai TA, Russell B. Three-dimensional culture with stiff microstructures increases proliferation and slows osteogenic differentiation of human mesenchymal stem cells. Small. 2010 Feb 5; 6(3):355-60. PMID: 19943257; PMCID: PMC2918279.

    View in: PubMed, PubMed Central

  8. Bernards DA, Desai TA. Nanoscale porosity in polymer films: fabrication and therapeutic applications. Soft Matter. 2010 Jan 1; 6(8):1621-1631. PMID: 22140398.

    View in: PubMed

  9. Peng L, Barczak AJ, Barbeau RA, Xiao Y, LaTempa TJ, Grimes CA, Desai TA. Whole genome expression analysis reveals differential effects of TiO2 nanotubes on vascular cells. Nano Lett. 2010 Jan; 10(1):143-8. PMID: 20030358; PMCID: PMC2833360.

    View in: PubMed, PubMed Central

  10. Mendelsohn A, Desai T. Inorganic nanoporous membranes for immunoisolated cell-based drug delivery. Adv Exp Med Biol. 2010; 670:104-25. PMID: 20384222; PMCID: PMC4046704.

    View in: PubMed, PubMed Central

  11. Desai TA. In the spotlight: tissue engineering. IEEE Rev Biomed Eng. 2010; 3:23-4. PMID: 22275199.

    View in: PubMed

  12. Ainslie KM, Tao SL, Popat KC, Daniels H, Hardev V, Grimes CA, Desai TA. In vitro inflammatory response of nanostructured titania, silicon oxide, and polycaprolactone. J Biomed Mater Res A. 2009 Dec; 91(3):647-55. PMID: 18988278.

    View in: PubMed

  13. Ainslie KM, Lowe RD, Beaudette TT, Petty L, Bachelder EM, Desai TA. Microfabricated devices for enhanced bioadhesive drug delivery: attachment to and small-molecule release through a cell monolayer under flow. Small. 2009 Dec; 5(24):2857-63. PMID: 19787677.

    View in: PubMed

  14. Biehl JK, Yamanaka S, Desai TA, Boheler KR, Russell B. Proliferation of mouse embryonic stem cell progeny and the spontaneous contractile activity of cardiomyocytes are affected by microtopography. Dev Dyn. 2009 Aug; 238(8):1964-73. PMID: 19618471; PMCID: PMC3717369.

    View in: PubMed, PubMed Central

  15. Peng L, Mendelsohn AD, LaTempa TJ, Yoriya S, Grimes CA, Desai TA. Long-term small molecule and protein elution from TiO2 nanotubes. Nano Lett. 2009 May; 9(5):1932-6. PMID: 19323554.

    View in: PubMed

  16. Fischer KE, Alemán BJ, Tao SL, Hugh Daniels R, Li EM, Bünger MD, Nagaraj G, Singh P, Zettl A, Desai TA. Biomimetic nanowire coatings for next generation adhesive drug delivery systems. Nano Lett. 2009 Feb; 9(2):716-20. PMID: 19199759; PMCID: PMC2824765.

    View in: PubMed, PubMed Central

  17. Desai TA. In the spotlight: tissue engineering--quantitative analysis of complex 3-D tissues. IEEE Rev Biomed Eng. 2009; 2:21-2. PMID: 22275041.

    View in: PubMed

  18. Peng L, Eltgroth ML, LaTempa TJ, Grimes CA, Desai TA. The effect of TiO2 nanotubes on endothelial function and smooth muscle proliferation. Biomaterials. 2009 Mar; 30(7):1268-72. PMID: 19081625.

    View in: PubMed

  19. Ainslie KM, Desai TA. Microfabricated implants for applications in therapeutic delivery, tissue engineering, and biosensing. Lab Chip. 2008 Nov; 8(11):1864-78. PMID: 18941687; PMCID: PMC2970504.

    View in: PubMed, PubMed Central

  20. Thakar RG, Chown MG, Patel A, Peng L, Kumar S, Desai TA. Contractility-dependent modulation of cell proliferation and adhesion by microscale topographical cues. Small. 2008 Sep; 4(9):1416-24. PMID: 18711756.

    View in: PubMed

  21. Pattani VP, Li C, Desai TA, Vu TQ. Microcontact printing of quantum dot bioconjugate arrays for localized capture and detection of biomolecules. Biomed Microdevices. 2008 Jun; 10(3):367-74. PMID: 18183489.

    View in: PubMed

  22. Redenti S, Tao S, Yang J, Gu P, Klassen H, Saigal S, Desai T, Young MJ. Retinal tissue engineering using mouse retinal progenitor cells and a novel biodegradable, thin-film poly(e-caprolactone) nanowire scaffold. J Ocul Biol Dis Infor. 2008 Mar; 1(1):19-29. PMID: 20072632; PMCID: PMC2802414.

    View in: PubMed, PubMed Central

  23. Ainslie KM, Kraning CM, Desai TA. Microfabrication of an asymmetric, multi-layered microdevice for controlled release of orally delivered therapeutics. Lab Chip. 2008 Jul; 8(7):1042-7. PMID: 18584077; PMCID: PMC2969854.

    View in: PubMed, PubMed Central

  24. Ainslie KM, Tao SL, Popat KC, Desai TA. In vitro immunogenicity of silicon-based micro- and nanostructured surfaces. ACS Nano. 2008 May; 2(5):1076-84. PMID: 19206506.

    View in: PubMed

  25. Norman JJ, Collins JM, Sharma S, Russell B, Desai TA. Microstructures in 3D biological gels affect cell proliferation. Tissue Eng Part A. 2008 Mar; 14(3):379-90. PMID: 18333790.

    View in: PubMed

  26. Nehilla BJ, Allen PG, Desai TA. Surfactant-free, drug-quantum-dot coloaded poly(lactide-co-glycolide) nanoparticles: towards multifunctional nanoparticles. ACS Nano. 2008 Mar; 2(3):538-44. PMID: 19206580.

    View in: PubMed

  27. Tao SL, Popat KC, Norman JJ, Desai TA. Surface modification of SU-8 for enhanced biofunctionality and nonfouling properties. Langmuir. 2008 Mar 18; 24(6):2631-6. PMID: 18275232.

    View in: PubMed

  28. Houtchens GR, Foster MD, Desai TA, Morgan EF, Wong JY. Combined effects of microtopography and cyclic strain on vascular smooth muscle cell orientation. J Biomech. 2008; 41(4):762-9. PMID: 18222460; PMCID: PMC2365919.

    View in: PubMed, PubMed Central

  29. Desai TA. In the Spotlight: Tissue and Molecular Engineering. IEEE Rev Biomed Eng. 2008; 1:21-2. PMID: 22274897.

    View in: PubMed

  30. Sarkar S, Isenberg BC, Hodis E, Leach JB, Desai TA, Wong JY. Fabrication of a layered microstructured polycaprolactone construct for 3-D tissue engineering. J Biomater Sci Polym Ed. 2008; 19(10):1347-62. PMID: 18854127; PMCID: PMC2737474.

    View in: PubMed, PubMed Central

  31. Neeley WL, Redenti S, Klassen H, Tao S, Desai T, Young MJ, Langer R. A microfabricated scaffold for retinal progenitor cell grafting. Biomaterials. 2008 Feb; 29(4):418-26. PMID: 17961646; PMCID: PMC2174396.

    View in: PubMed, PubMed Central

  32. Nehilla BJ, Bergkvist M, Popat KC, Desai TA. Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles. Int J Pharm. 2008 Feb 4; 348(1-2):107-14. PMID: 17692482.

    View in: PubMed

  33. Popat KC, Eltgroth M, LaTempa TJ, Grimes CA, Desai TA. Titania nanotubes: a novel platform for drug-eluting coatings for medical implants? Small. 2007 Nov; 3(11):1878-81. PMID: 17935080.

    View in: PubMed

  34. Popat KC, Eltgroth M, Latempa TJ, Grimes CA, Desai TA. Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes. Biomaterials. 2007 Nov; 28(32):4880-8. PMID: 17697708.

    View in: PubMed

  35. Tao SL, Desai TA. Aligned arrays of biodegradable poly(epsilon-caprolactone) nanowires and nanofibers by template synthesis. Nano Lett. 2007 Jun; 7(6):1463-8. PMID: 17488047.

    View in: PubMed

  36. Tan W, Vinegoni C, Norman JJ, Desai TA, Boppart SA. Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Tech. 2007 Apr; 70(4):361-71. PMID: 17262787.

    View in: PubMed

  37. Tao S, Young C, Redenti S, Zhang Y, Klassen H, Desai T, Young MJ. Survival, migration and differentiation of retinal progenitor cells transplanted on micro-machined poly(methyl methacrylate) scaffolds to the subretinal space. Lab Chip. 2007 Jun; 7(6):695-701. PMID: 17538710.

    View in: PubMed

  38. Popat KC, Leoni L, Grimes CA, Desai TA. Influence of engineered titania nanotubular surfaces on bone cells. Biomaterials. 2007 Jul; 28(21):3188-97. PMID: 17449092.

    View in: PubMed

  39. Popat KC, Chatvanichkul KI, Barnes GL, Latempa TJ, Grimes CA, Desai TA. Osteogenic differentiation of marrow stromal cells cultured on nanoporous alumina surfaces. J Biomed Mater Res A. 2007 Mar 15; 80(4):955-64. PMID: 17089417.

    View in: PubMed

  40. La Flamme KE, Popat KC, Leoni L, Markiewicz E, La Tempa TJ, Roman BB, Grimes CA, Desai TA. Biocompatibility of nanoporous alumina membranes for immunoisolation. Biomaterials. 2007 Jun; 28(16):2638-45. PMID: 17335895; PMCID: PMC3225223.

    View in: PubMed, PubMed Central

  41. La Flamme KE, LaTempa TJ, Grimes CA, Desai TA. The effects of cell density and device arrangement on the behavior of macroencapsulated beta-cells. Cell Transplant. 2007; 16(8):765-74. PMID: 18087997.

    View in: PubMed

  42. Tan W, Oldenburg AL, Norman JJ, Desai TA, Boppart SA. Optical coherence tomography of cell dynamics in three-dimensional tissue models. Opt Express. 2006 Aug 7; 14(16):7159-71. PMID: 19529086.

    View in: PubMed

  43. Sarkar S, Lee GY, Wong JY, Desai TA. Development and characterization of a porous micro-patterned scaffold for vascular tissue engineering applications. Biomaterials. 2006 Sep; 27(27):4775-82. PMID: 16725195.

    View in: PubMed

  44. Popat KC, Daniels RH, Dubrow RS, Hardev V, Desai TA. Nanostructured surfaces for bone biotemplating applications. J Orthop Res. 2006 Apr; 24(4):619-27. PMID: 16514643.

    View in: PubMed

  45. Ohno S, Schmid T, Tanne Y, Kamiya T, Honda K, Ohno-Nakahara M, Swentko N, Desai TA, Tanne K, Knudson CB, Knudson W. Expression of superficial zone protein in mandibular condyle cartilage. Osteoarthritis Cartilage. 2006 Aug; 14(8):807-13. PMID: 16563813; PMCID: PMC3182505.

    View in: PubMed, PubMed Central

  46. Norman JJ, Desai TA. Methods for fabrication of nanoscale topography for tissue engineering scaffolds. Ann Biomed Eng. 2006 Jan; 34(1):89-101. PMID: 16525765.

    View in: PubMed

  47. Lopez CA, Fleischman AJ, Roy S, Desai TA. Evaluation of silicon nanoporous membranes and ECM-based microenvironments on neurosecretory cells. Biomaterials. 2006 Jun; 27(16):3075-83. PMID: 16457879.

    View in: PubMed

  48. Saltzman M, Desai T. Drug delivery in the BME curricula. Ann Biomed Eng. 2006 Feb; 34(2):270-5. PMID: 16450195.

    View in: PubMed

  49. Tao SL, Popat K, Desai TA. Off-wafer fabrication and surface modification of asymmetric 3D SU-8 microparticles. Nat Protoc. 2006; 1(6):3153-8. PMID: 17406578.

    View in: PubMed

  50. Gimi B, Leoni L, Oberholzer J, Braun M, Avila J, Wang Y, Desai T, Philipson LH, Magin RL, Roman BB. Functional MR microimaging of pancreatic beta-cell activation. Cell Transplant. 2006; 15(2):195-203. PMID: 16719054.

    View in: PubMed

  51. Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice LC, Brenner RM. Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth. Mol Hum Reprod. 2005 Nov; 11(11):791-9. PMID: 16390855.

    View in: PubMed

  52. Nehilla BJ, Vu TQ, Desai TA. Stoichiometry-dependent formation of quantum dot-antibody bioconjugates: a complementary atomic force microscopy and agarose gel electrophoresis study. J Phys Chem B. 2005 Nov 10; 109(44):20724-30. PMID: 16853686.

    View in: PubMed

  53. Tao SL, Desai TA. Micromachined devices: the impact of controlled geometry from cell-targeting to bioavailability. J Control Release. 2005 Dec 5; 109(1-3):127-38. PMID: 16274828.

    View in: PubMed

  54. La Flamme KE, Mor G, Gong D, La Tempa T, Fusaro VA, Grimes CA, Desai TA. Nanoporous alumina capsules for cellular macroencapsulation: transport and biocompatibility. Diabetes Technol Ther. 2005 Oct; 7(5):684-94. PMID: 16241869.

    View in: PubMed

  55. Popat KC, Leary Swan EE, Desai TA. Modeling of RGDC film parameters using X-ray photoelectron spectroscopy. Langmuir. 2005 Aug 2; 21(16):7061-5. PMID: 16042422.

    View in: PubMed

  56. Tao SL, Desai TA. Gastrointestinal patch systems for oral drug delivery. Drug Discov Today. 2005 Jul 1; 10(13):909-15. PMID: 15993810.

    View in: PubMed

  57. Swan EE, Popat KC, Desai TA. Peptide-immobilized nanoporous alumina membranes for enhanced osteoblast adhesion. Biomaterials. 2005 May; 26(14):1969-76. PMID: 15576171.

    View in: PubMed

  58. Vu TQ, Maddipati R, Blute TA, Nehilla BJ, Nusblat L, Desai TA. Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth. Nano Lett. 2005 Apr; 5(4):603-7. PMID: 15826094.

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  59. Swan EE, Popat KC, Grimes CA, Desai TA. Fabrication and evaluation of nanoporous alumina membranes for osteoblast culture. J Biomed Mater Res A. 2005 Mar 1; 72(3):288-95. PMID: 15654700.

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  60. Norman JJ, Desai TA. Control of cellular organization in three dimensions using a microfabricated polydimethylsiloxane-collagen composite tissue scaffold. Tissue Eng. 2005 Mar-Apr; 11(3-4):378-86. PMID: 15871668.

    View in: PubMed

  61. Tan W, Desai TA. Microscale multilayer cocultures for biomimetic blood vessels. J Biomed Mater Res A. 2005 Feb 1; 72(2):146-60. PMID: 15558555.

    View in: PubMed

  62. Sharma S, Desai TA. Nanostructured antifouling poly(ethylene glycol) films for silicon-based microsystems. J Nanosci Nanotechnol. 2005 Feb; 5(2):235-43. PMID: 15853141.

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  63. Sharma S, Tan W, Desai TA. Improving the integrity of three-dimensional vascular patterns by poly(ethylene glycol) conjugation. Bioconjug Chem. 2005 Jan-Feb; 16(1):18-22. PMID: 15656570.

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  64. Sarkar S, Dadhania M, Rourke P, Desai TA, Wong JY. Vascular tissue engineering: microtextured scaffold templates to control organization of vascular smooth muscle cells and extracellular matrix. Acta Biomater. 2005 Jan; 1(1):93-100. PMID: 16701783.

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  65. Popat KC, Leary Swan EE, Mukhatyar V, Chatvanichkul KI, Mor GK, Grimes CA, Desai TA. Influence of nanoporous alumina membranes on long-term osteoblast response. Biomaterials. 2005 Aug; 26(22):4516-22. PMID: 15722120.

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  66. Desai TA, West T, Cohen M, Boiarski T, Rampersaud A. Nanoporous microsystems for islet cell replacement. Adv Drug Deliv Rev. 2004 Sep 22; 56(11):1661-73. PMID: 15350295.

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  67. Sharma S, Johnson RW, Desai TA. XPS and AFM analysis of antifouling PEG interfaces for microfabricated silicon biosensors. Biosens Bioelectron. 2004 Sep 15; 20(2):227-39. PMID: 15308226.

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  68. Popat KC, Mor G, Grimes CA, Desai TA. Surface modification of nanoporous alumina surfaces with poly(ethylene glycol). Langmuir. 2004 Sep 14; 20(19):8035-41. PMID: 15350069.

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  69. Nehilla BJ, Popat KC, Vu TQ, Chowdhury S, Standaert RF, Pepperberg DR, Desai TA. Neurotransmitter analog tethered to a silicon platform for neuro-BioMEMS applications. Biotechnol Bioeng. 2004 Sep 5; 87(5):669-74. PMID: 15352065.

    View in: PubMed

  70. Cai Q, Zeng K, Ruan C, Desai TA, Grimes CA. A wireless, remote query glucose biosensor based on a pH-sensitive polymer. Anal Chem. 2004 Jul 15; 76(14):4038-43. PMID: 15253640.

    View in: PubMed

  71. Popat KC, Desai TA. Poly(ethylene glycol) interfaces: an approach for enhanced performance of microfluidic systems. Biosens Bioelectron. 2004 Apr 15; 19(9):1037-44. PMID: 15018959.

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  72. Tan W, Desai TA. Layer-by-layer microfluidics for biomimetic three-dimensional structures. Biomaterials. 2004 Mar-Apr; 25(7-8):1355-64. PMID: 14643610.

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  73. Leoni L, Desai TA. Micromachined biocapsules for cell-based sensing and delivery. Adv Drug Deliv Rev. 2004 Feb 10; 56(2):211-29. PMID: 14741117.

    View in: PubMed

  74. Sharma S, Johnson RW, Desai TA. Evaluation of the stability of nonfouling ultrathin poly(ethylene glycol) films for silicon-based microdevices. Langmuir. 2004 Jan 20; 20(2):348-56. PMID: 15743077.

    View in: PubMed

  75. Attiah DG, Kopher RA, Desai TA. Characterization of PC12 cell proliferation and differentiation-stimulated by ECM adhesion proteins and neurotrophic factors. J Mater Sci Mater Med. 2003 Nov; 14(11):1005-9. PMID: 15348515.

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  76. Tao SL, Lubeley MW, Desai TA. Synthesis of cytoadhesive poly(methylmethacrylate) for applications in targeted drug delivery. J Biomed Mater Res A. 2003 Nov 1; 67(2):369-75. PMID: 14619915.

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  77. Motlagh D, Hartman TJ, Desai TA, Russell B. Microfabricated grooves recapitulate neonatal myocyte connexin43 and N-cadherin expression and localization. J Biomed Mater Res A. 2003 Oct 1; 67(1):148-57. PMID: 14517872.

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  78. Saifuddin U, Vu TQ, Rezac M, Qian H, Pepperberg DR, Desai TA. Assembly and characterization of biofunctional neurotransmitter-immobilized surfaces for interaction with postsynaptic membrane receptors. J Biomed Mater Res A. 2003 Jul 1; 66(1):184-91. PMID: 12833445.

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  79. Motlagh D, Senyo SE, Desai TA, Russell B. Microtextured substrata alter gene expression, protein localization and the shape of cardiac myocytes. Biomaterials. 2003 Jun; 24(14):2463-76. PMID: 12695073.

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  80. Boateng SY, Hartman TJ, Ahluwalia N, Vidula H, Desai TA, Russell B. Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography. Am J Physiol Cell Physiol. 2003 Jul; 285(1):C171-82. PMID: 12672651.

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  81. Tan W, Desai TA. Microfluidic patterning of cells in extracellular matrix biopolymers: effects of channel size, cell type, and matrix composition on pattern integrity. Tissue Eng. 2003 Apr; 9(2):255-67. PMID: 12740088.

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  82. Tao SL, Lubeley MW, Desai TA. Bioadhesive poly(methyl methacrylate) microdevices for controlled drug delivery. J Control Release. 2003 Mar 7; 88(2):215-28. PMID: 12628329.

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  83. Tao SL, Desai TA. Microfabricated drug delivery systems: from particles to pores. Adv Drug Deliv Rev. 2003 Feb 24; 55(3):315-28. PMID: 12628319.

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  84. Davis DH, Giannoulis CS, Johnson RW, Desai TA. Immobilization of RGD to < 1 1 1 > silicon surfaces for enhanced cell adhesion and proliferation. Biomaterials. 2002 Oct; 23(19):4019-27. PMID: 12162335.

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  85. Desai TA. Microfabrication technology for pancreatic cell encapsulation. Expert Opin Biol Ther. 2002 Aug; 2(6):633-46. PMID: 12171507.

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  86. Ahmed A, Bonner C, Desai TA. Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery. J Control Release. 2002 Jun 17; 81(3):291-306. PMID: 12044568.

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  87. Giannoulis CS, Desai TA. Characterization of proteins and fibroblasts on thin inorganic films. J Mater Sci Mater Med. 2002 Jan; 13(1):75-80. PMID: 15348209.

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  88. Weis RP, Montchamp JL, Coffer JL, Attiah DG, Desai TA. Calcified nanostructured silicon wafer surfaces for biosensing: effects of surface modification on bioactivity. Dis Markers. 2002; 18(4):159-65. PMID: 12590169; PMCID: PMC3850822.

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  89. Leoni L, Desai TA. Nanoporous biocapsules for the encapsulation of insulinoma cells: biotransport and biocompatibility considerations. IEEE Trans Biomed Eng. 2001 Nov; 48(11):1335-41. PMID: 11686632.

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  90. Tan W, Krishnaraj R, Desai TA. Evaluation of nanostructured composite collagen--chitosan matrices for tissue engineering. Tissue Eng. 2001 Apr; 7(2):203-10. PMID: 11304455.

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  91. Snyder JD, Desai TA. Microscale three-dimensional polymeric platforms for in vitro cell culture systems. J Biomater Sci Polym Ed. 2001; 12(8):921-32. PMID: 11718485.

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2000 and earlier

  1. Desai TA. Micro- and nanoscale structures for tissue engineering constructs. Med Eng Phys. 2000 Nov; 22(9):595-606. PMID: 11259928.

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  2. Desai TA, Hansford DJ, Ferrari M. Micromachined interfaces: new approaches in cell immunoisolation and biomolecular separation. Biomol Eng. 2000 Oct; 17(1):23-36. PMID: 11042474.

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  3. Desai TA, Hansford DJ, Leoni L, Essenpreis M, Ferrari M. Nanoporous anti-fouling silicon membranes for biosensor applications. Biosens Bioelectron. 2000; 15(9-10):453-62. PMID: 11419640.

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  4. Deutsch J, Motlagh D, Russell B, Desai TA. Fabrication of microtextured membranes for cardiac myocyte attachment and orientation. J Biomed Mater Res. 2000; 53(3):267-75. PMID: 10813767.

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  5. Desai TA, Chu WH, Rasi G, Sinibaldi-Vallebona P, Guarino E, Ferrari M. Microfabricated biocapsules provide short-term immunoisolation of insulinoma xenografts. Biomed Microdevices. 1999; 1(2):131-8. PMID: 16281113.

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  6. Zhang M, Desai T, Ferrari M. Proteins and cells on PEG immobilized silicon surfaces. Biomaterials. 1998 May; 19(10):953-60. PMID: 9690837.

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  7. Desai TA, Chu WH, Tu JK, Beattie GM, Hayek A, Ferrari M. Microfabricated immunoisolating biocapsules. Biotechnol Bioeng. 1998 Jan 5; 57(1):118-20. PMID: 10099185.

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  8. Wang W, Wu W, Desai T, Ward DC, Kaufman SJ. Localization of the alpha 7 integrin gene (ITGA7) on human chromosome 12q13: clustering of integrin and Hox genes implies parallel evolution of these gene families. Genomics. 1995 Apr 10; 26(3):568-70. PMID: 7607681.

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