Shared resources for the NCIBT include the extensive UC Davis research infrastructure of both Davis and Sacramento campuses that enables studies spanning from benchtop to industry dissemination.
HPC2
NCIBT HPC2 GPU Node
The UC Davis High-Performance Computing Core Facility (HPCCF) is a campus research core facility in the Office of Research specializing in high-performance computing (HPC) systems for research and education.
As part of the HPCCF mission, they manage high-performance computing services that enable practical innovation at the UC Davis Research Community to enhance the university's competitive advantage. NCIBT has purchased a GPU node in the HPC2 cluster that is available for all NCIBT collaborators.
Benchtop
Center for Nano-Micro Manufacturing (CNM2)
The UC Davis Center for Nano-MicroManufacturing (CNM2) is equipped with the fabrication tools needed to carry out the proposed research and education activities. The CNM2 is the home for the prototype and fabrication of thin-film, micro- and nano-structures. CNM2 is housed in a 10,000 ft2 Class-1000 and -100 clean room that provides capabilities for fabricating integrated circuits and assembling hybrid modules. To support these activities, CNM2 is fully equipped with photolithography, etching, mask-making, metal deposition, and furnaces, vacuum systems, and assembly equipment. NCIBT will leverage CNM2, with professional staff support and state-of-the-art equipment for benchtop development of device prototypes for NCIBT research.
TEAM (Translating Engineering Advances to Medicine) Design, Prototyping, and Fabrication Facility
This facility seeks to accelerate the adoption and commercialization of newly developed technologies through aid in design and inexpensive rapid prototyping techniques. TEAM’s goal is to facilitate prototyping, so that engineers and innovators can test their ideas and get them into production and on the market with minimal delay. The TEAM prototyping facility will be able to support manufacturing and prototyping needs of the NCIBT.
Center for Data Science and Artificial Intelligence Reserach (CeDAR)
CeDAR addresses the great challenges of our society by translating complex data into powerful solutions. The center has the opportunity and resources to bring together world renowned experts from many fields of study with top data science and artificial intelligence researchers. This promotes a highly efficient exchange of information and expertise that enhances real world data science applications. CeDAR will provide their expertise on data science and artificial intelligence to assist the development of AI tools in TRD 3.
UC Davis TETRAPODS Institute of Data Science (UCD4IDS)
UCD4IDS promotes interdisciplinary research collaborations among faculty members, postdocs, and graduate students coming from four departments (Computer Science, Electrical & Computer Engineering, Mathematics, and Statistics). The project encourages innovative and robust research and provides education and mentoring of graduate students and postdocs in data science. The UCD4IDS will bring in the insights gained by the experience of the faculty members in the four primary departments as well as application fields such as neuroscience, medical and health sciences, and veterinary medicine. UCD4IDS will develop and examine feature extraction methodologies for image diagnostics for NCIBT.
Preclinical Translation
Center for Molecular and Genomic Imaging (CMGI)
CMGI is a world-class, fully equipped core facility that provides in vivo animal imaging and biospecimen imaging. A biomedical cyclotron and radiochemistry laboratory allow on-site synthesis of custom radiotracers. NCIBT will utilize CMGI facility infrastructure to provide an efficient platform for medical imaging technology development that directly addresses the preclinical translational needs of this project.
Surgical Research Facility (SRF)
SRF is managed by a team of professionals devoted to providing quality research and teaching opportunities through the responsible use of animals. SRF is a facility where quality science merges with animal welfare, and it is dedicated to improving the lives of both animals and mankind. An on-site full-time veterinarian oversees and participates in research projects along with highly specialized technical support staff with extensive experience in surgery and anesthesia. Services include proof of concept, prototype development, safety testing, efficacy testing, device validation and verification, training, animal model based training, didactic training, sponsor-designed product-specific instructional courses, surgeon-to-surgeon training, pre-clinical testing, and biocompatibility.
California National Primate Reserach Center (CNPRC)
CNPRC is a part of the National Primate Research Centers Program and is dedicated to improving human and animal health. The CNPRC is one of seven such centers supported by the National Institutes of Health. The National Primate Research Centers are a unique resource for investigators studying human health and disease, offering the opportunity to assess the causes of disease and new treatment methods in nonhuman primate models that closely recapitulate the human scenario.
CNPRC will assist in the development and testing of NCIBT imaging technologies that warrant testing in primates before they are used in humans. CNPRC is further eager to consider adding both iFLIm and iNIRS to the imaging armamentarium of imaging core; this would allow CNPRC to employ them in their own models of human diseases and eventually to offer them as part of the imaging menu for clients. These multiple synergies will facilitate the research, expand the capabilities, and promote the dissemination of both NCIBT and CNPRC programs.
Clinical Translation
Clinical and Translational Science Center (CTSC)
The UC Davis CTSC was one of the inaugural Clinical and Translational Award sites and over the last 15 years has transformed the clinical and translational research enterprise at UC Davis. CTSC’s mission is to create research teams of the future to improve human health through provision of research resources, development, demonstration, and dissemination of innovative processes and methods, cutting edge informatics, and community engagement.
The CTSC provides centralized resources to facilitate translation of new technologies such as those of NCIBT. It offers support for all aspects of clinical trial development and of training of clinical investigators, both of which will be available to the NCIBT. The CTSC will provide the NCIBT with expertise and resources - in areas including trial design, application for IRB approval, regulatory compliance, and rigorous analysis of results - needed to plan, implement, and conclude the clinical trials of its technologies. CTSC expertise in education and training will be available to the NCIBT as it develops and executes its strategies for education, training, and dissemination.
UC Biomedical Research Acceleration Integration and Development (UC BRAID)
UC BRAID, a consortium of five University of California health campuses – UC Davis, Irvine, Los Angeles, San Diego and San Francisco – aims to accelerate research through shared resources, processes, and infrastructure development. UC BRAID connects researchers and administrators to solve problems, increase opportunities, and create efficiency of scale. Its platform of shared governance acts as a catalyst for collaboration, enabling to amplify individual work and multiply the impact of technological advancements such as those anticipated from NCIBT. UC BRAID believes the Hubs can be stronger than the sum of their parts.
UC BRAID will eagerly and effectively support dissemination and clinical testing of new optical clinical technology. the collaboration of the major health systems of the University of California opens a high caliber conduit for rapid dissemination of NCIBT technologies and tools to a vast network eager to share research and clinical trials.
UC Davis Comprehensive Cancer Center (UCDCCC)
UCDCCC's mission is to generate discoveries to increase understanding of cancer's biology, improve cancer prevention, diagnosis, and treatment for populations in its diverse catchment area and beyond, and prepare trainees as leaders in cancer care and research.
The UCDCCC will provide full access to the Center's shared resources, including the biorepository, biostatistics capabilities, and access to the clinical trials office to ensure the success of NCIBT. The Cancer Center will commit to supporting the training and career development of under-represented early career investigators engaged in translational and clinical research in alignment with NCIBT's efforts to optimize DEI and cancer health equity.
Technology Translation and Dissemination
UC Davis Office of Research: Innovation and Technology Commercialization
The goal of Innovation and Technology Commercialization at UC Davis is to help transform today’s research and development into tomorrow’s successful businesses, ensuring that nascent technologies emerging from campus research will be the seed for tomorrow’s successful products, services, and economic development. The success of ITC is based on the close working relationships of its staff with faculty and personnel within academic and administrative units across the campus, as well as its effective engagement with the local economic community, including government, business, and not-for-profit organizations.
UC Davis Innovation and Technology Commercialization Office will facilitate NCIBT to achieve the goal of accelerating the development and dissemination of new biomedical technologies.