(Q53863989)

21 May 2018

http://europepmc.org/abstract/MED/12697873

title

Phase II Trial of Intravenous CI-1042 in Patients With Metastatic Colorectal Cancer (English)

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

24 December 2023

main subject

phase II clinical trial

0 references

0 references

1 reference

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

24 December 2023

6

Evanthia Galanis

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

author name string

Oday Hamid

1

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

Scott Wadler

3

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

Al Benson

5

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

Margaret Uprichard

7

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

Charles Omer

8

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

Paul Bycott

9

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

Mary L. Varterasian

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697873

24 December 2023

J. Randolph Hecht

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697873

24 December 2023

Robert C. Hackman

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697873

24 December 2023

Anthony F. Shields

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697873

24 December 2023

language of work or name

English

0 references

publication date

1 April 2003

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

15 April 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12697873

full work available at URL

24 December 2023

https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2003.09.114

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

Journal of Clinical Oncology

24 December 2023

published in

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

volume

21

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

issue

8

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21 May 2018

http://europepmc.org/abstract/MED/12697873

page(s)

1498-1504

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21 May 2018

http://europepmc.org/abstract/MED/12697873

cites work

The chemotherapy of colon cancer can no longer be ignored

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

24 December 2023

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Dissection of functional domains in the adenovirus 2 early 1B 55K polypeptide by suppressor-linker insertional mutagenesis

24 December 2023

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Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription

24 December 2023

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p53 and DNA polymerase alpha compete for binding to SV40 T antigen

24 December 2023

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

24 December 2023

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p53-dependent cell death/apoptosis is required for a productive adenovirus infection

24 December 2023

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ONYX-015: clinical data are encouraging

24 December 2023

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Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

24 December 2023

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Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

24 December 2023

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Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

24 December 2023

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Optimal two-stage designs for phase II clinical trials

24 December 2023

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Adenovirus infections in patients undergoing bone-marrow transplantation.

24 December 2023

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a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

24 December 2023

15

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

24 December 2023

16

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer

24 December 2023

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Antineoplastic agents 360. Synthesis and cancer cell growth inhibitory studies of dolastatin 15 structural modifications

24 December 2023

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1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

24 December 2023

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1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

Pre-existent adenovirus antibody inhibits systemic toxicity and antitumor activity of CN706 in the nude mouse LNCaP xenograft model: implications and proposals for human therapy

24 December 2023

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https://api.crossref.org/works/10.1200/JCO.2003.09.114

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

24 December 2023

23

1 reference

https://api.crossref.org/works/10.1200/JCO.2003.09.114

24 December 2023

Identifiers

1 reference

21 May 2018

http://europepmc.org/abstract/MED/12697873

1 reference

21 May 2018