(Q33912833)

English

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

scientific article published in August 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

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head and neck carcinoma

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5

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Tannock IF

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30 July 2017

author name string

Khuri FR

1

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30 July 2017

Nemunaitis J

2

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30 July 2017

Ganly I

3

1 reference

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30 July 2017

Arseneau J

4

1 reference

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30 July 2017

Romel L

6

1 reference

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30 July 2017

Gore M

7

1 reference

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30 July 2017

Ironside J

8

1 reference

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30 July 2017

MacDougall RH

9

1 reference

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30 July 2017

Heise C

10

1 reference

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30 July 2017

Randlev B

11

1 reference

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30 July 2017

Gillenwater AM

12

1 reference

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30 July 2017

Bruso P

13

1 reference

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30 July 2017

Kaye SB

14

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30 July 2017

Hong WK

15

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30 July 2017

Kirn DH

16

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30 July 2017

language of work or name

0 references

publication date

1 August 2000

1 reference

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30 July 2017

Nature Medicine

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30 July 2017

6

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30 July 2017

8

1 reference

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30 July 2017

879-885

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer statistics, 2000.

1 reference

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Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck

1 reference

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Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

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7 January 2021

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Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

1 reference

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Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

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A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck

1 reference

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Prospective randomized trial of high-dose cisplatin and fluorouracil infusion with or without sodium diethyldithiocarbamate in recurrent and/or metastatic squamous cell carcinoma of the head and neck

1 reference

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Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck

1 reference

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7 January 2021

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Phase III trial of modulation of cisplatin/fluorouracil chemotherapy by interferon alfa-2b in patients with recurrent or metastatic head and neck cancer. Head and Neck Interferon Cooperative Study Group

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

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A phase III randomised trial of cistplatinum, methotrextate, cisplatinum + methotrexate and cisplatinum + 5-FU in end stage squamous carcinoma of the head and neck. Liverpool Head and Neck Oncology Group

1 reference

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7 January 2021

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Evaluation of high-dose cisplatin and 5-FU infusion as initial therapy in advanced head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

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Improved complete response rate and survival in advanced head and neck cancer after three-course induction therapy with 120-hour 5-FU infusion and cisplatin.

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent cell death/apoptosis is required for a productive adenovirus infection

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

ONYX-015: clinical data are encouraging

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

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p53 status and the efficacy of cancer therapy in vivo

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

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Synergy between the herpes simplex virus tk/ganciclovir prodrug suicide system and the topoisomerase I inhibitor topotecan

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

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The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor: still a promising agent

1 reference

https://api.crossref.org/works/10.1038%2F78638

7 January 2021

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A randomised phase II study of carmustine alone or in combination with tumour necrosis factor in patients with advanced melanoma

1 reference

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7 January 2021

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Tumour necrosis factor in man: clinical and biological observations

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7 January 2021

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A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

1 reference

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7 January 2021

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Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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Europe PubMed Central

PubMed publication ID

30 July 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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